Name: Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Fab-Fv)
SKU: FABFV-H350
Rating: 5 (1 reviews)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-TG antibody are fused with the VL and VH domains of an anti-TPO antibody respectively. It can form natural in vivo heterodimerization. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Datasheet INQUIRY

Specifications

Targets

TG & TPO

Type

Fab-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune thyroid disease

Targets

Target 1

Gene ID

7038

UniProt ID

P01266

Alternative Names

AITD3, TG; thyroglobulin; TGN

Target 2

TPO

Gene ID

7173

UniProt ID

P07202

Alternative Names

MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Fab-Fv) (CAT#: FABFV-H350)

Specifications

Targets

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