Home > Products > TG & TPO > Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Fab-Fv)

Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Fab-Fv)  (FABFV-H350)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-TG antibody are fused with the VL and VH domains of an anti-TPO antibody respectively. It can form natural in vivo heterodimerization. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Specifications

Targets
TG & TPO
Type
Fab-Fv
Species Reactivity
Human
Target 1
TG
Host Animal 1
Human
Target 2
TPO
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune thyroid disease

Targets

Target 1
TG
Gene ID
UniProt ID
Alternative Names
AITD3, TG; thyroglobulin; TGN
Target 2
TPO
Gene ID
UniProt ID
Alternative Names
MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

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