Name: Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Fv-IgG)
SKU: BSDG-H351
Rating: 5 (1 reviews)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-TG IgG with similar domains from an anti-TPO antibody via short peptide linkers, or vice versa. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Datasheet INQUIRY

Specifications

Targets

TG & TPO

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune thyroid disease

Targets

Target 1

Gene ID

7038

UniProt ID

P01266

Alternative Names

AITD3, TG; thyroglobulin; TGN

Target 2

TPO

Gene ID

7173

UniProt ID

P07202

Alternative Names

MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Fv-IgG) (CAT#: BSDG-H351)

Specifications

Targets

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