Name: Recombinant Anti-TG x Anti-TPO Bispecific Antibody (IgG(L)-scFv)
SKU: IGLFV-189
Rating: 5 (1 reviews)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-TG antibody are fused to the C terminus of an anti-TPO IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Datasheet INQUIRY

Specifications

Targets

TG & TPO

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune thyroid disease

Targets

Target 1

Gene ID

7038

UniProt ID

P01266

Alternative Names

AITD3, TG; thyroglobulin; TGN

Target 2

TPO

Gene ID

7173

UniProt ID

P07202

Alternative Names

MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-TG x Anti-TPO Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-189)

Specifications

Targets

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