Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Miniantibody) (MNAB-189)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-TG antibody variable domain is linked to another scFv of an anti-TPO antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

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Specifications

Targets

TG & TPO

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Autoimmune thyroid disease

Targets

Target 1

Gene ID

7038

UniProt ID

P01266

Alternative Names

AITD3, TG; thyroglobulin; TGN

Target 2

TPO

Gene ID

7173

UniProt ID

P07202

Alternative Names

MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Miniantibody) (CAT#: MNAB-189)

Specifications

Targets

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