Home > Products > TG & TPO > Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Miniantibody)

Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (Miniantibody)  (MNAB-H351)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-TG antibody variable domain is linked to another scFv of an anti-TPO antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Specifications
Targets
TG & TPO
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
TG
Host Animal 1
Mouse
Target 2
TPO
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune thyroid disease
Targets
Target 1
TG
Gene ID
UniProt ID
Alternative Names
AITD3, TG; thyroglobulin; TGN
Target 2
TPO
Gene ID
UniProt ID
Alternative Names
MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF
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