Home > Products > TG & TPO > Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (scFv-Fc)

Recombinant Human Anti-TG x Human Anti-TPO Bispecific Antibody (scFv-Fc)  (BSCFV-H351)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-TG specificity or anti-TPO specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Specifications

Targets
TG & TPO
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
TG
Host Animal 1
Mouse
Target 2
TPO
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune thyroid disease

Targets

Target 1
TG
Gene ID
UniProt ID
Alternative Names
AITD3, TG; thyroglobulin; TGN
Target 2
TPO
Gene ID
UniProt ID
Alternative Names
MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

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