Home > Products > TG & TPO > Recombinant Anti-TG x Anti-TPO Bispecific Antibody (TandAb)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (TandAb)  (TANDAB-189)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (TandAb) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Specifications
Targets
TG & TPO
Type
TandAb
Species Reactivity
Human
Target 1
TG
Host Animal 1
Mouse
Target 2
TPO
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune thyroid disease
Targets
Target 1
TG
Gene ID
UniProt ID
Alternative Names
AITD3, TG; thyroglobulin; TGN
Target 2
TPO
Gene ID
UniProt ID
Alternative Names
MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF
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