Home > Products > TG & TPO > Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Triple Body)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Triple Body)  (TRIB-189)

Recombinant Anti-TG x Anti-TPO Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-TG antibody are both extended with the scFv fragment from an anti-TPO antibody. This BsAb can bind two antigens simultaneously and block the synthesis of thyroid hormones. It is designed for the research of Autoimmune thyroid disease therapy.

Specifications

Targets
TG & TPO
Type
Triple Body
Species Reactivity
Human
Target 1
TG
Host Animal 1
Mouse
Target 2
TPO
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune thyroid disease

Targets

Target 1
TG
Gene ID
UniProt ID
Alternative Names
AITD3, TG; thyroglobulin; TGN
Target 2
TPO
Gene ID
UniProt ID
Alternative Names
MSA; TPX; TDH2A; TPPO; thrombopoietin; megakaryocyte growth and development factor; MGDF

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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