Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-IgG) (FABIG-190)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

VEGFB & VEGF

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFB

Gene ID

7423

UniProt ID

P49765

Alternative Names

VRF; VEGFL; VEGFB; vascular endothelial growth factor B

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-IgG) (CAT#: FABIG-190)

Specifications

Targets

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