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Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-CH3)  (CAT#: BSDBC-190)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-VEGFB and anti-VEGF antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.
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Specifications

Targets
VEGFB & VEGF
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers

Targets

Target 1
VEGFB
Gene ID
UniProt ID
Alternative Names
VRF; VEGFL; VEGFB; vascular endothelial growth factor B
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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