Home > Products > VEGFB & VEGF > Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-Fc)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-Fc)  (BSDBF-190)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-VEGFB and anti-VEGF antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

Specifications
Targets
VEGFB & VEGF
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
VEGFB
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers
Targets
Target 1
VEGFB
Gene ID
UniProt ID
Alternative Names
VRF; VEGFL; VEGFB; vascular endothelial growth factor B
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
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