Home > Products > VEGFB & VEGF > Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2)  (BABFV-190)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-VEGFB specificity is fused to the C terminus of the anti-VEGF Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

Specifications
Targets
VEGFB & VEGF
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
VEGFB
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers
Targets
Target 1
VEGFB
Gene ID
UniProt ID
Alternative Names
VRF; VEGFL; VEGFB; vascular endothelial growth factor B
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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