Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) (BABFV-H352)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-VEGFB specificity is fused to the C terminus of the anti-VEGF Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

VEGFB & VEGF

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFB

Gene ID

7423

UniProt ID

P49765

Alternative Names

VRF; VEGFL; VEGFB; vascular endothelial growth factor B

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-H352)

Specifications

Targets

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