Home > Products > VEGFB & VEGF > Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG(L)-scFv)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG(L)-scFv)  (IGLFV-190)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-VEGFB antibody are fused to the C terminus of an anti-VEGF IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

Specifications
Targets
VEGFB & VEGF
Type
Appended IgGs
Species Reactivity
Human
Target 1
VEGFB
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers
Targets
Target 1
VEGFB
Gene ID
UniProt ID
Alternative Names
VRF; VEGFL; VEGFB; vascular endothelial growth factor B
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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