Home > Products > VEGFB & VEGF > Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-CH3)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-CH3)  (BSFC-H352)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-CH3) contains two chains. The anti-VEGFB scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

Specifications
Targets
VEGFB & VEGF
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
VEGFB
Host Animal 1
Mouse
Target 2
VEGF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers
Targets
Target 1
VEGFB
Gene ID
UniProt ID
Alternative Names
VRF; VEGFL; VEGFB; vascular endothelial growth factor B
Target 2
VEGF
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

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