Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-CH3) (BSFC-H352)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-CH3) contains two chains. The anti-VEGFB scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

VEGFB & VEGF

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFB

Gene ID

7423

UniProt ID

P49765

Alternative Names

VRF; VEGFL; VEGFB; vascular endothelial growth factor B

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H352)

Specifications

Targets

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