Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-Fc-scFv) (BSTF-190)

Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-VEGFB scFv is fused to the N-terminus of Fc via a hinge region while another anti-VEGF scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can block two proangiogenics simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

VEGFB & VEGF

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFB

Gene ID

7423

UniProt ID

P49765

Alternative Names

VRF; VEGFL; VEGFB; vascular endothelial growth factor B

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-190)

Specifications

Targets

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