Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (Fab-IgG) (FABIG-191)

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

VEGFR2 & VEGFR3

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Target 2

VEGFR3

Gene ID

2324

UniProt ID

P35916

Alternative Names

FLT4; PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3; fms related tyrosine kinase 4; Vascular endothelial growth factor 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (Fab-IgG) (CAT#: FABIG-191)

Specifications

Targets

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