Bispecific aptamers represent a cutting-edge class of targeting molecules designed to engage two distinct targets with high specificity and affinity simultaneously. Structurally, these molecules are typically composed of two independent aptamer sequences, each engineered to bind a unique ligand, which are then covalently linked. This linkage can be achieved through various methods, including direct fusion, flexible linkers, or scaffold-based approaches, dictating the overall architectural stability and binding orientation. Their inherent flexibility and small size, characteristic of aptamers, allow for versatile binding to diverse targets, including proteins, cells, and small molecules. This dual-targeting capability enables enhanced therapeutic and diagnostic applications, such as improved cellular targeting, controlled drug delivery, and intricate biosensing, by leveraging synergistic binding effects for superior functional outcomes.
| CAT# | Product Name | Species Reactivity | BsAb Type | Target 1 | Host Animal 1 | Target 2 | Host Animal 2 | INQUIRY |
|---|---|---|---|---|---|---|---|---|
| KN-0825-JL74 | Anti-IGF2R x Anti-MET Bispecific aptamer (DNA/DNA) | Human | Bispecific Aptamer | IGF2R | MET | Inquiry | ||
| KN-0825-JL73 | Anti-CD44 x Anti-EPCAM Bispecific aptamer (RNA/RNA) | Human | Bispecific Aptamer | CD44 | EPCAM | Inquiry | ||
| KN-0825-JL7 | Anti-MRP1 x Anti-CD28 Bispecific aptamer (RNA/RNA) | Human | Bispecific Aptamer | MRP1 | CD28 | Inquiry | ||
| KN-0825-JL4 | Anti-CD62L x Anti-PD-L1 Bispecific aptamer (DNA/DNA) | Human | Bispecific Aptamer | CD62L | PD-L1 | Inquiry | ||
| KN-0825-JL2 | Anti-CD16 x Anti-MET Bispecific aptamer (DNA/DNA) | Human | Bispecific Aptamer | CD16 | MET | Inquiry | ||
| KN-0825-JL1 | Anti-CD16 x Anti-MUC1 Bispecific aptamer (DNA/DNA) | Human | Bispecific Aptamer | CD16 | MUC1 | Inquiry | ||
| KN-0825-JL8 | Anti-PSMA x Anti-4-1BB Bispecific aptamer (RNA/RNA) | Human | Bispecific Aptamer | PSMA | 4-1BB | Inquiry | ||
| KN-0825-JL6 | Anti-OPN x Anti-4-1BB Bispecific aptamer (RNA/RNA) | Human | Bispecific Aptamer | OPN | 4-1BB | Inquiry | ||
| KN-0825-JL5 | Anti-VEGF x Anti-4-1BB Bispecific aptamer (RNA/RNA) | Human | Bispecific Aptamer | VEGF | 4-1BB | Inquiry | ||
| KN-0825-JL3 | Anti-CD62L x Anti-PTK7 Bispecific aptamer (DNA/DNA) | Human | Bispecific Aptamer | CD62L | PTK7 | Inquiry |
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