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Bispecific Aptamer Products

Bispecific aptamers represent a cutting-edge class of targeting molecules designed to engage two distinct targets with high specificity and affinity simultaneously. Structurally, these molecules are typically composed of two independent aptamer sequences, each engineered to bind a unique ligand, which are then covalently linked. This linkage can be achieved through various methods, including direct fusion, flexible linkers, or scaffold-based approaches, dictating the overall architectural stability and binding orientation. Their inherent flexibility and small size, characteristic of aptamers, allow for versatile binding to diverse targets, including proteins, cells, and small molecules. This dual-targeting capability enables enhanced therapeutic and diagnostic applications, such as improved cellular targeting, controlled drug delivery, and intricate biosensing, by leveraging synergistic binding effects for superior functional outcomes.

Schematic diagram of bispecific aptamers. (Creative Biolabs AI)

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
KN-0825-JL74 Anti-IGF2R x Anti-MET Bispecific aptamer (DNA/DNA) Human Bispecific Aptamer IGF2R MET Inquiry
KN-0825-JL73 Anti-CD44 x Anti-EPCAM Bispecific aptamer (RNA/RNA) Human Bispecific Aptamer CD44 EPCAM Inquiry
KN-0825-JL7 Anti-MRP1 x Anti-CD28 Bispecific aptamer (RNA/RNA) Human Bispecific Aptamer MRP1 CD28 Inquiry
KN-0825-JL4 Anti-CD62L x Anti-PD-L1 Bispecific aptamer (DNA/DNA) Human Bispecific Aptamer CD62L PD-L1 Inquiry
KN-0825-JL2 Anti-CD16 x Anti-MET Bispecific aptamer (DNA/DNA) Human Bispecific Aptamer CD16 MET Inquiry
KN-0825-JL1 Anti-CD16 x Anti-MUC1 Bispecific aptamer (DNA/DNA) Human Bispecific Aptamer CD16 MUC1 Inquiry
KN-0825-JL8 Anti-PSMA x Anti-4-1BB Bispecific aptamer (RNA/RNA) Human Bispecific Aptamer PSMA 4-1BB Inquiry
KN-0825-JL6 Anti-OPN x Anti-4-1BB Bispecific aptamer (RNA/RNA) Human Bispecific Aptamer OPN 4-1BB Inquiry
KN-0825-JL5 Anti-VEGF x Anti-4-1BB Bispecific aptamer (RNA/RNA) Human Bispecific Aptamer VEGF 4-1BB Inquiry
KN-0825-JL3 Anti-CD62L x Anti-PTK7 Bispecific aptamer (DNA/DNA) Human Bispecific Aptamer CD62L PTK7 Inquiry

Background

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