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Fab-Fv

Fab-scFv is a type of bispecific fragments. The heavy chain Fd fragment and the light chain of an antibody Fab fragment form natural in vivo heterodimerization. The heterodimerization module can be used as a scaffold, upon which, additional functions, such as variable domains, are incorporated. The Fab and Fv portion can both be against target antigens and serve as dual inhibitors or engagers. This format can also have been applied to extend the half-life of the Fab moiety, with Fab against a target antigen and Fv against serum albumin. The molecule weight of Fab-Fv is ~75 kDa. Base on the structure of Fab-Fv, interdomain disulfide bond can be introduced into the Fv domain to generate a Fab-dsFv molecule. Fab-dsFv molecules have also been proven to be biophysically stable and retain affinity for both antigens.

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
FABFV-100 Recombinant Anti-CD3 x Anti-PSA Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse PSA Mouse Inquiry
FABFV-099 Recombinant Anti-CD3 x Anti-PLAP Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse PLAP Mouse Inquiry
FABFV-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse PD1 Mouse Inquiry
FABFV-097 Recombinant Anti-CD3 x Anti-p97 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse p97 Mouse Inquiry
FABFV-096 Recombinant Anti-CD3 x Anti-P cadherin Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse P-Cadherin Mouse Inquiry
FABFV-095 Recombinant Anti-CD3 x Anti-MUC1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse MUC1 Mouse Inquiry
FABFV-094 Recombinant Anti-CD3 x Anti-CSPG4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CSPG4 Mouse Inquiry
FABFV-093 Recombinant Anti-CD3 x Anti-IL2R Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse IL2R Mouse Inquiry
FABFV-092 Recombinant Anti-CD3 x Anti-IGF1R Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse IGF1R Mouse Inquiry
FABFV-091 Recombinant Anti-CD3 x Anti-HN Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse HN Mouse Inquiry
FABFV-090 Recombinant Anti-CD3 x Anti-HER2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse HER2 Mouse Inquiry
FABFV-089 Recombinant Anti-CD3 x Anti-HBVgp3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse HBVgp3 Mouse Inquiry
FABFV-088 Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse GPNMB Mouse Inquiry
FABFV-087 Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse GPC3 Mouse Inquiry
FABFV-086 Recombinant Anti-CD3 x Anti-gpA33 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse gpA33 Mouse Inquiry
FABFV-085 Recombinant Anti-CD3 x Anti-HIV-1 gp41 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse HIV-1 gp41 Mouse Inquiry
FABFV-084 Recombinant Anti-CD3 x Anti-HIV-1 gp120 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse HIV-1 gp120 Mouse Inquiry
FABFV-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse GD2 Mouse Inquiry
FABFV-082 Recombinant Anti-CD3 x Anti-FOLR1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse FOLR1 Mouse Inquiry
FABFV-081 Recombinant Anti-CD3 x Anti-FcRH5 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse FcRH5 Mouse Inquiry
FABFV-080 Recombinant Anti-CD3 x Anti-FAP Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse FAP Mouse Inquiry
FABFV-079 Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse EPCAM Mouse Inquiry
FABFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD248 Mouse Inquiry
FABFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse EGFR Mouse Inquiry
FABFV-076 Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse DLL3 Mouse Inquiry
FABFV-075 Recombinant Anti-CD3 x Anti-CXCR5 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CXCR5 Mouse Inquiry
FABFV-074 Recombinant Anti-CD3 x Anti-MET Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse MET Mouse Inquiry
FABFV-073 Recombinant Anti-CD3 x Anti-CLEC12A Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CLEC12A Mouse Inquiry
FABFV-072 Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CEA Mouse Inquiry
FABFV-071 Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD8 Mouse Inquiry
FABFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD79B Mouse Inquiry
FABFV-069 Recombinant Anti-CD3 x Anti-CD74 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD74 Mouse Inquiry
FABFV-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD44 Mouse Inquiry
FABFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD4 Mouse Inquiry
FABFV-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD33 Mouse Inquiry
FABFV-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD30 Mouse Inquiry
FABFV-064 Recombinant Anti-CD3 x Anti-B7H3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse B7H3 Mouse Inquiry
FABFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CSPG4 Mouse Inquiry
FABFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse MUC1 Mouse Inquiry
FABFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse HN Mouse Inquiry
FABFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse FOLR1 Mouse Inquiry
FABFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse EPCAM Mouse Inquiry
FABFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse EGFR Mouse Inquiry
FABFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CD44 Mouse Inquiry
FABFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CD40 Mouse Inquiry
FABFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CD30 Mouse Inquiry
FABFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CD3 Mouse Inquiry
FABFV-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Fab-Fv) Human Fab-Fv CD22 Mouse Saporin Mouse Inquiry
FABFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 Mouse CD47 Mouse Inquiry
FABFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 Mouse CD3 Mouse Inquiry
FABFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 Mouse CD28 Mouse Inquiry
FABFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 Mouse CD22 Mouse Inquiry
FABFV-048 Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (Fab-Fv) Mouse Fab-Fv CD2 Mouse TCR (Vβ8) Mouse Inquiry
FABFV-047 Recombinant Anti-CD2 x Anti-MUC1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD2 Mouse MUC1 Mouse Inquiry
FABFV-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD2 Mouse EGFR Mouse Inquiry
FABFV-045 Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD89 Mouse Inquiry
FABFV-044 Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD64 Mouse Inquiry
FABFV-043 Recombinant Anti-CD19 x Anti-CD59 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD59 Mouse Inquiry
FABFV-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD47 Mouse Inquiry
FABFV-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD3 Mouse Inquiry
FABFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD28 Mouse Inquiry
FABFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD22 Mouse Inquiry
FABFV-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Mouse HER2 Mouse Inquiry
FABFV-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Mouse GD2 Mouse Inquiry
FABFV-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Mouse EGFR Mouse Inquiry
FABFV-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Mouse CD32B Mouse Inquiry
FABFV-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Mouse CD30 Mouse Inquiry
FABFV-033 Recombinant Anti-CD15 x Anti-DENV Bispecific Antibody (Fab-Fv) Human Fab-Fv CD15 Mouse DENV Mouse Inquiry
FABFV-032 Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD15 Mouse CD64 Mouse Inquiry
FABFV-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD133 Mouse EGFR Mouse Inquiry
FABFV-030 Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD123 Mouse CD3 Mouse Inquiry
FABFV-029 Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CCR5 Mouse CD3 Mouse Inquiry
FABFV-028 Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Fab-Fv) Human Fab-Fv CCR3 Mouse CD300 Mouse Inquiry
FABFV-027 Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CA72-4 Mouse CD3 Mouse Inquiry
FABFV-026 Recombinant Anti-CA19-9 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CA19-9 Mouse CD3 Mouse Inquiry
FABFV-025 Recombinant Anti-CA125 x Anti-HER2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CA125 Mouse HER2 Mouse Inquiry
FABFV-024 Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Fab-Fv) Human Fab-Fv C5 Mouse HRP Mouse Inquiry
FABFV-023 Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (Fab-Fv) Human Fab-Fv C. albicans Mouse CD64 Mouse Inquiry
FABFV-022 Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Fab-Fv) Fab-Fv Biotin Mouse HRP Mouse Inquiry
FABFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-Fv) Human Fab-Fv BCMA Mouse TACI Mouse Inquiry
FABFV-020 Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv BCMA Mouse CD3 Mouse Inquiry
FABFV-019 Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (Fab-Fv) Human Fab-Fv BAFF Mouse IL17 Mouse Inquiry
FABFV-018 Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (Fab-Fv) Human Fab-Fv BAFF Mouse B7RP1 Mouse Inquiry
FABFV-017 Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv B7H6 Mouse CD3 Mouse Inquiry
FABFV-016 Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma BCL1 Idiotype Rat CD3 Mouse Inquiry
FABFV-015 Recombinant Anti-B Cell Lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma A20-HL Idiotype Rat CD3 Mouse Inquiry
FABFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
FABFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Fab-Fv) Human Fab-Fv AR Mouse DNA Mouse Inquiry
FABFV-011 Recombinant Anti-AP (Alkaline Phosphatase) x Anti-LPA Bispecific Antibody (Fab-Fv) Human Fab-Fv AP (Alkaline Phosphatase) Mouse LPA Mouse Inquiry
FABFV-010 Recombinant Anti-AP (Alkaline Phosphatase) x Anti-CEA Bispecific Antibody (Fab-Fv) Human Fab-Fv AP (Alkaline Phosphatase) Mouse CEA Mouse Inquiry
FABFV-009 Recombinant Anti-AP (Alkaline Phosphatase) x Anti-7-OHC (7-hydroxycoumarin) Bispecific Antibody (Fab-Fv) Human Fab-Fv AP (Alkaline Phosphatase) Mouse 7-OHC (7-hydroxycoumarin) Mouse Inquiry
FABFV-008 Recombinant Anti-Ang2 x Anti-VEGFA Bispecific Antibody (Fab-Fv) Human Fab-Fv Ang2 Mouse VEGFA Mouse Inquiry
FABFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Mouse TNF Mouse Inquiry
FABFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Mouse IL-6R Mouse Inquiry
FABFV-005 Recombinant Anti-Ad Fiber Knob x Anti-ITGAV Bispecific Antibody (Fab-Fv) Human Fab-Fv Ad Fiber Knob Mouse ITGAV Mouse Inquiry
FABFV-004 Recombinant Anti-Ad Fiber Knob x Anti-EPCAM Bispecific Antibody (Fab-Fv) Human Fab-Fv Ad Fiber Knob Mouse EPCAM Mouse Inquiry
FABFV-003 Recombinant Anti-Ad Fiber Knob x Anti-CEA Bispecific Antibody (Fab-Fv) Human Fab-Fv Ad Fiber Knob Mouse CEA Mouse Inquiry
FABFV-002 Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Fab-Fv) Human Fab-Fv Ad Fiber Knob Mouse CD40 Mouse Inquiry
FABFV-001 Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma BCL1 Idiotype Rat CD64 Mouse Inquiry

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