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Anti-MRP1 x Anti-CD28 Bispecific aptamer (RNA/RNA)  (CAT#: KN-0825-JL7)

Anti-MRP1 x Anti-CD28 Bispecific aptamer (RNA/RNA) consists of an anti-MRP1 RNA aptamer and a dimeric anti-CD28 RNA aptamer. It has 1+2 antigen-binding valency for MRP1 and CD28 respectively. This bispecific aptamer (BsApt) can retarget T cells to chemotherapy-resistant tumors expressing MRP1 . It is designed for the research of Solid tumors therapy.
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Specifications

Targets
MRP1 & CD28
Type
Bispecific Aptamer
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors

Targets

Target 1
MRP1
Gene ID
UniProt ID
Alternative Names
Multidrug Resistance-Associated Protein 1; ABCC1; ATP-binding cassette sub-family C member 1; ATP-binding cassette transporter ABCC1; MRP; ABCC; GS-X; MRP1; ABC29; DFNA77; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter
Target 2
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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