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Albumin & IL-6R Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H192 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Tandem Diabody) Human Tandem Diabody albumin Human IL-6R Human Inquiry
T-BSDB-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Tandem Diabody) Human Tandem Diabody albumin Mouse IL-6R Mouse Inquiry
SCIGG-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scIgG) Human Single chain IgGs Albumin Human IL-6R Human Inquiry
FABVC-356 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Fab-sdAb-Fc) Human Fab-scFv/sdAb-Fc albumin Mouse IL-6R llama Inquiry
BSSG-356 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (sdAb-IgG) Human sdAb-IgG albumin Mouse IL-6R llama Inquiry
HCAB-001 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (sdAb-Fc-sdAb) Human sdAb-Fc-sdAb albumin llama IL-6R llama Inquiry
BIBD-356 Recombinant Anti-Albumin x Anti-IL-6R VHH BispecificAntibody (Bibody) Human Bibody Albumin Mouse IL-6R llama Inquiry
IGVHH-001 Recombinant Anti-albumin x Anti-IL-6R sdAb VBispecific Antibody (IgG-sdAb) Human IgG-sdAb albumin Mouse IL-6R llama Inquiry
BIVHH-001 Recombinant Anti-Albumin sdAb x Anti-IL-6R sdAb Bispecific Antibody (Bi-sdAb) Human Bi-sdAb Albumin llama IL-6R llama Inquiry
SCIGG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scIgG) Human Single chain IgGs Albumin Mouse IL-6R Mouse Inquiry
FVTIG-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv4-Ig) Human scFv4-Ig albumin Human IL-6R Human Inquiry
FVTIG-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv4-Ig) Human scFv4-Ig albumin Mouse IL-6R Mouse Inquiry
BSSG-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-IgG) Human scFv-IgG albumin Human IL-6R Human Inquiry
BSSG-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-IgG) Human scFv-IgG albumin Mouse IL-6R Mouse Inquiry
IGLFV-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv albumin Human IL-6R Human Inquiry
IGLFV-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv albumin Mouse IL-6R Mouse Inquiry
BSGV-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (IgG-Fv) Human IgG-Fv albumin Mouse IL-6R Mouse Inquiry
BSGV-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (IgG-Fv) Human IgG-Fv albumin Mouse IL-6R Mouse Inquiry
BSDG-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Fv-IgG) Human Fv-IgG albumin Human IL-6R Human Inquiry
BSDG-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Fv-IgG) Human Fv-IgG albumin Mouse IL-6R Mouse Inquiry
BABFV-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 albumin Human IL-6R Human Inquiry
BABFV-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 albumin Mouse IL-6R Mouse Inquiry
FABVC-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc albumin Human IL-6R Human Inquiry
FABVC-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc albumin Mouse IL-6R Mouse Inquiry
SCDBC-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 albumin Human IL-6R Human Inquiry
SCDBC-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 albumin Mouse IL-6R Mouse Inquiry
BSDBC-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 albumin Human IL-6R Human Inquiry
BSDBC-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 albumin Mouse IL-6R Mouse Inquiry
SCDBF-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc albumin Human IL-6R Human Inquiry
SCDBF-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc albumin Mouse IL-6R Mouse Inquiry
BSFVF-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc albumin Human IL-6R Human Inquiry
BSFVF-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc albumin Mouse IL-6R Mouse Inquiry
BSDBF-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Diabody-Fc) Human Diabody-Fc albumin Human IL-6R Human Inquiry
BSDBF-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Diabody-Fc) Human Diabody-Fc albumin Mouse IL-6R Mouse Inquiry
BSTF-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv albumin Mouse IL-6R Mouse Inquiry
BSTF-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv albumin Mouse IL-6R Mouse Inquiry
BSCFV-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc) Human scFv-Fc albumin Mouse IL-6R Mouse Inquiry
BSCFV-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc) Human scFv-Fc albumin Mouse IL-6R Mouse Inquiry
MNAB-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (Miniantibody) Human Miniantibody albumin Mouse IL-6R Mouse Inquiry
MNAB-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Miniantibody) Human Miniantibody albumin Mouse IL-6R Mouse Inquiry
BSFC-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-CH3) Human scFv-CH3 albumin Mouse IL-6R Mouse Inquiry
BSFC-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-CH3) Human scFv-CH3 albumin Mouse IL-6R Mouse Inquiry
BSCC-H194 Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL albumin Mouse IL-6R Mouse Inquiry
BSCC-006 Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL albumin Mouse IL-6R Mouse Inquiry
BIBD-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Bibody) Human Bibody Albumin Mouse IL-6R Mouse Inquiry
BIBD-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Bibody) Human Bibody Albumin Mouse IL-6R Mouse Inquiry
FABFV-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Human IL-6R Human Inquiry
FABFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Mouse IL-6R Mouse Inquiry
MiniB-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Minibody) Human Minibody Albumin Human IL-6R Human Inquiry
MiniB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Minibody) Human Minibody Albumin Mouse IL-6R Mouse Inquiry
SCDB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin Human IL-6R Human Inquiry
FABIG-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin Human IL-6R Human Inquiry
TRIB-H194 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv Albumin Human IL-6R Human Inquiry
BSIG-H192 Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin Human IL-6R Human Inquiry
CROSSAB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (CrossMab) Human CrossMab Albumin Human IL-6R Human Inquiry
IGFV-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin Human IL-6R Human Inquiry
BSDB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Diabody) Human Diabody Albumin Human IL-6R Human Inquiry
BSFAB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin Human IL-6R Human Inquiry
BSFV-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin Human IL-6R Human Inquiry
SCDB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin Mouse IL-6R Mouse Inquiry
FABIG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin Mouse IL-6R Mouse Inquiry
TRIB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv Albumin Mouse IL-6R Mouse Inquiry
BSIG-006 Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin Mouse IL-6R Mouse Inquiry
CROSSAB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (CrossMab) Human CrossMab Albumin Mouse IL-6R Mouse Inquiry
IGFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin Mouse IL-6R Mouse Inquiry
BSDB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Diabody) Human Diabody Albumin Mouse IL-6R Mouse Inquiry
BSFAB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin Mouse IL-6R Mouse Inquiry
BSFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin Mouse IL-6R Mouse Inquiry
BSDG-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Fv-IgG) Human Fv-IgG albumin Human TNF Human Inquiry
BSDG-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Fv-IgG) Human Fv-IgG albumin Mouse TNF Mouse Inquiry
BABFV-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 albumin Human TNF Human Inquiry
BABFV-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 albumin Mouse TNF Mouse Inquiry
FABVC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc albumin Human TNF Human Inquiry
FABVC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc albumin Mouse TNF Mouse Inquiry
SCDBC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 albumin Human TNF Human Inquiry
SCDBC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 albumin Mouse TNF Mouse Inquiry
BSDBC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 albumin Human TNF Human Inquiry
BSDBC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 albumin Mouse TNF Mouse Inquiry
SCDBF-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc albumin Human TNF Human Inquiry
SCDBF-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc albumin Mouse TNF Mouse Inquiry
BSFVF-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc albumin Human TNF Human Inquiry
BSFVF-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc albumin Mouse TNF Mouse Inquiry
BSDBF-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Diabody-Fc) Human Diabody-Fc albumin Human TNF Human Inquiry
BSDBF-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Diabody-Fc) Human Diabody-Fc albumin Mouse TNF Mouse Inquiry
BSTF-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv albumin Mouse TNF Mouse Inquiry
BSTF-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv albumin Mouse TNF Mouse Inquiry
BSCFV-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc albumin Mouse TNF Mouse Inquiry
BSCFV-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc albumin Mouse TNF Mouse Inquiry
MNAB-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody albumin Mouse TNF Mouse Inquiry
MNAB-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody albumin Mouse TNF Mouse Inquiry
BSFC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 albumin Mouse TNF Mouse Inquiry
BSFC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 albumin Mouse TNF Mouse Inquiry
BSCC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL albumin Mouse TNF Mouse Inquiry
BSCC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL albumin Mouse TNF Mouse Inquiry
BIBD-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Bibody) Human Bibody Albumin Mouse TNF Mouse Inquiry
BIBD-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Bibody) Human Bibody Albumin Mouse TNF Mouse Inquiry
FABFV-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Human TNF Human Inquiry
FABFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Mouse TNF Mouse Inquiry
MiniB-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Minibody) Human Minibody Albumin Human TNF Human Inquiry
MiniB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Minibody) Human Minibody Albumin Mouse TNF Mouse Inquiry
SCDB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin Human TNF Human Inquiry
FABIG-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin Human TNF Human Inquiry
TRIB-H195 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv Albumin Human TNF Human Inquiry
BSIG-H193 Human Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin Human TNF Human Inquiry
CROSSAB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab Albumin Human TNF Human Inquiry
IGFV-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin Human TNF Human Inquiry
BSDB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody) Human Diabody Albumin Human TNF Human Inquiry
BSFAB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin Human TNF Human Inquiry
BSFV-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin Human TNF Human Inquiry
SCDB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin Mouse TNF Mouse Inquiry
FABIG-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin Mouse TNF Mouse Inquiry
TRIB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv Albumin Mouse TNF Mouse Inquiry
BSIG-007 Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin Mouse TNF Mouse Inquiry
CROSSAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab Albumin Mouse TNF Mouse Inquiry
IGFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin Mouse TNF Mouse Inquiry
BSDB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody) Human Diabody Albumin Mouse TNF Mouse Inquiry
BSFAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin Mouse TNF Mouse Inquiry
BSFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin Mouse TNF Mouse Inquiry

Background

Albumin is a protein synthesized by the liver that acts as a carrier molecule for many molecules in the blood, including drugs. IL-6R (Interleukin-6 receptor) is a receptor found on the surface of various cells including immune cells, that is involved in the inflammatory response and plays a role in immune regulation. The anti-albumin×anti-IL-6R bispecific antibody (BsAb) is designed to bind to albumin in the blood and IL-6R on target cells, effectively delivering therapeutic agents specifically to IL-6R-expressing cells. This approach allows for targeted therapy while utilizing the natural transport function of albumin. This BsAb can be used in the research of inflammatory and autoimmune diseases such as rheumatoid arthritis and Crohn's disease. It may also have potential applications in cancer therapy, as IL-6 plays a role in tumor growth and metastasis.

Fig.1 Human serum albumin and IL-6R structures. (Larsen, et al., 2016; By Emw - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/wiki/File:Protein_IL6R_PDB_1n26.png) Fig.1 Crystal structures of human serum albumin and IL-6R.1,2

References

  1. Larsen, Maja Thim, et al. "Albumin-based drug delivery: harnessing nature to cure disease." Molecular and Cellular Therapies 4.1 (2016): 1-12.
  2. From Wikipedia: By Emw - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/wiki/File:Protein_IL6R_PDB_1n26.png
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