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Albumin & IL-6R Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem Diabody) Human Albumin IL-6R Inquiry
T-BSDB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem Diabody) Human Albumin IL-6R Inquiry
SCIGG-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scIgG) Human Single chain IgGs Albumin IL-6R Inquiry
FABVC-356 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-VHH-Fc) Human Fab-Fc Fusion Proteins Albumin IL-6R Inquiry
BSSG-356 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (VHH-IgG) Human Appended IgGs Albumin IL-6R Inquiry
HCAB-001 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (VHH-Fc-VHH) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BIBD-356 Recombinant Anti-Albumin x Anti-IL-6R VHH BispecificAntibody (Bibody) Human Bibody Albumin IL-6R Inquiry
IGVHH-001 Recombinant Anti-Albumin x Anti-IL-6R VHH VBispecificAntibody (IgG-VHH) Human Appended IgGs Albumin IL-6R Inquiry
BIVHH-001 Recombinant Anti-Albumin VHH x Anti-IL-6R VHH BispecificAntibody (Bi-sdAb) Human Bi-sdAb Albumin IL-6R Inquiry
SCIGG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scIgG) Human Single chain IgGs Albumin IL-6R Inquiry
FVTIG-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scFv4-Ig) Human Appended IgGs Albumin IL-6R Inquiry
FVTIG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scFv4-Ig) Human Appended IgGs Albumin IL-6R Inquiry
BSSG-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scFv-IgG) Human Appended IgGs Albumin IL-6R Inquiry
BSSG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scFv-IgG) Human Appended IgGs Albumin IL-6R Inquiry
IGLFV-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs Albumin IL-6R Inquiry
IGLFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs Albumin IL-6R Inquiry
BSGV-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (IgG-Fv) Human IgG-Fv Albumin IL-6R Inquiry
BSGV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-Fv) Human IgG-Fv Albumin IL-6R Inquiry
BSDG-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Fv-IgG) Human Appended IgGs Albumin IL-6R Inquiry
BSDG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fv-IgG) Human Appended IgGs Albumin IL-6R Inquiry
BABFV-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins Albumin IL-6R Inquiry
BABFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins Albumin IL-6R Inquiry
FABVC-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins Albumin IL-6R Inquiry
FABVC-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins Albumin IL-6R Inquiry
SCDBC-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
SCDBC-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSDBC-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSDBC-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
SCDBF-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
SCDBF-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSFVF-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSFVF-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSDBF-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSDBF-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin IL-6R Inquiry
BSTF-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSTF-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSCFV-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSCFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
MNAB-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
MNAB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSFC-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSFC-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSCC-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BSCC-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments Albumin IL-6R Inquiry
BIBD-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Bibody) Human Bibody Albumin IL-6R Inquiry
BIBD-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Bibody) Human Bibody Albumin IL-6R Inquiry
FABFV-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin IL-6R Inquiry
FABFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin IL-6R Inquiry
MiniB-H194 Recombinant Human Anti-Albumin x Human Anti-IL-6R Bispecific Antibody (Minibody) Human Minibody Albumin IL-6R Inquiry
MiniB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Minibody) Human Minibody Albumin IL-6R Inquiry
SCDB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin IL-6R Inquiry
FABIG-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin IL-6R Inquiry
TRIB-H194 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Triple Body) Human Triple Body Albumin IL-6R Inquiry
BSIG-H192 Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin IL-6R Inquiry
CROSSAB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (CrossMab) Human CrossMab Albumin IL-6R Inquiry
IGFV-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin IL-6R Inquiry
BSDB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Diabody) Human Diabody Albumin IL-6R Inquiry
BSFAB-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin IL-6R Inquiry
BSFV-H192 Recombinant Human Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin IL-6R Inquiry
SCDB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin IL-6R Inquiry
FABIG-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin IL-6R Inquiry
TRIB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Triple Body) Human Triple Body Albumin IL-6R Inquiry
BSIG-006 Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin IL-6R Inquiry
CROSSAB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (CrossMab) Human CrossMab Albumin IL-6R Inquiry
IGFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin IL-6R Inquiry
BSDB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Diabody) Human Diabody Albumin IL-6R Inquiry
BSFAB-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin IL-6R Inquiry
BSFV-006 Recombinant Anti-Albumin x Anti-IL-6R Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin IL-6R Inquiry
BSDG-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Fv-IgG) Human Appended IgGs Albumin TNF Inquiry
BSDG-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fv-IgG) Human Appended IgGs Albumin TNF Inquiry
BABFV-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins Albumin TNF Inquiry
BABFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins Albumin TNF Inquiry
FABVC-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins Albumin TNF Inquiry
FABVC-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins Albumin TNF Inquiry
SCDBC-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
SCDBC-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSDBC-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSDBC-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
SCDBF-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
SCDBF-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSFVF-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSFVF-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSDBF-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSDBF-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments Albumin TNF Inquiry
BSTF-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSTF-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSCFV-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSCFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
MNAB-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
MNAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSFC-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSFC-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSCC-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BSCC-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments Albumin TNF Inquiry
BIBD-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Bibody) Human Bibody Albumin TNF Inquiry
BIBD-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Bibody) Human Bibody Albumin TNF Inquiry
FABFV-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin TNF Inquiry
FABFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin TNF Inquiry
MiniB-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Minibody) Human Minibody Albumin TNF Inquiry
MiniB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Minibody) Human Minibody Albumin TNF Inquiry
SCDB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin TNF Inquiry
FABIG-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin TNF Inquiry
TRIB-H195 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Triple Body) Human Triple Body Albumin TNF Inquiry
BSIG-H193 Human Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin TNF Inquiry
CROSSAB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab Albumin TNF Inquiry
IGFV-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin TNF Inquiry
BSDB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody) Human Diabody Albumin TNF Inquiry
BSFAB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin TNF Inquiry
BSFV-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin TNF Inquiry
SCDB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin TNF Inquiry
FABIG-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin TNF Inquiry
TRIB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Triple Body) Human Triple Body Albumin TNF Inquiry
BSIG-007 Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin TNF Inquiry
CROSSAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab Albumin TNF Inquiry
IGFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin TNF Inquiry
BSDB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody) Human Diabody Albumin TNF Inquiry
BSFAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin TNF Inquiry
BSFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin TNF Inquiry

Background

Albumin is a protein synthesized by the liver that acts as a carrier molecule for many molecules in the blood, including drugs. IL-6R (Interleukin-6 receptor) is a receptor found on the surface of various cells including immune cells, that is involved in the inflammatory response and plays a role in immune regulation. The anti-albumin×anti-IL-6R bispecific antibody (BsAb) is designed to bind to albumin in the blood and IL-6R on target cells, effectively delivering therapeutic agents specifically to IL-6R-expressing cells. This approach allows for targeted therapy while utilizing the natural transport function of albumin. This BsAb can be used in the research of inflammatory and autoimmune diseases such as rheumatoid arthritis and Crohn's disease. It may also have potential applications in cancer therapy, as IL-6 plays a role in tumor growth and metastasis.

Fig.1 Human serum albumin and IL-6R structures. (Larsen, et al., 2016; By Emw - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/wiki/File:Protein_IL6R_PDB_1n26.png) Fig.1 Crystal structures of human serum albumin and IL-6R.1,2

References

  1. Larsen, Maja Thim, et al. "Albumin-based drug delivery: harnessing nature to cure disease." Molecular and Cellular Therapies 4.1 (2016): 1-12.
  2. From Wikipedia: By Emw - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/wiki/File:Protein_IL6R_PDB_1n26.png
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