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AR & DNA Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Tandem Diabody) Human Tandem Diabody AR Mouse DNA Mouse Inquiry
SCIGG-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scIgG) Human Single chain IgGs AR Mouse DNA Mouse Inquiry
FVTIG-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv4-Ig) Human scFv4-Ig AR Mouse DNA Mouse Inquiry
BSSG-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-IgG) Human scFv-IgG AR Mouse DNA Mouse Inquiry
IGLFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv AR Mouse DNA Mouse Inquiry
BSGV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (IgG-Fv) Human IgG-Fv AR Mouse DNA Mouse Inquiry
BSDG-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Fv-IgG) Human Fv-IgG AR Mouse DNA Mouse Inquiry
BABFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 AR Mouse DNA Mouse Inquiry
FABVC-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc AR Mouse DNA Mouse Inquiry
SCDBC-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 AR Mouse DNA Mouse Inquiry
BSDBC-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 AR Mouse DNA Mouse Inquiry
SCDBF-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc AR Mouse DNA Mouse Inquiry
BSFVF-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc AR Mouse DNA Mouse Inquiry
BSDBF-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Diabody-Fc) Human Diabody-Fc AR Mouse DNA Mouse Inquiry
BSTF-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv AR Mouse DNA Mouse Inquiry
BSCFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-Fc) Human scFv-Fc AR Mouse DNA Mouse Inquiry
MNAB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Miniantibody) Human Miniantibody AR Mouse DNA Mouse Inquiry
BSFC-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-CH3) Human scFv-CH3 AR Mouse DNA Mouse Inquiry
BSCC-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL AR Mouse DNA Mouse Inquiry
BIBD-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Bibody) Human Bibody AR Mouse DNA Mouse Inquiry
FABFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Fab-Fv) Human Fab-Fv AR Mouse DNA Mouse Inquiry
MiniB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Minibody) Human Minibody AR Mouse DNA Mouse Inquiry
SCDB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody AR Mouse DNA Mouse Inquiry
FABIG-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Fab-IgG) Human Fab-IgG AR Mouse DNA Mouse Inquiry
TRIB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv AR Mouse DNA Mouse Inquiry
BSIG-012 Anti-AR x Anti-DNA Bispecific Antibody (IgG-IgG) Human IgG-IgG AR Mouse DNA Mouse Inquiry
CROSSAB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (CrossMab) Human CrossMab AR Mouse DNA Mouse Inquiry
IGFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (IgG-scFv) Human IgG-scFv AR Mouse DNA Mouse Inquiry
BSDB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Diabody) Human Diabody AR Mouse DNA Mouse Inquiry
BSFAB-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Tandem Fab) Human Tandem Fab AR Mouse DNA Mouse Inquiry
BSFV-012 Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Tandem scFv) Human Tandem scFv AR Mouse DNA Mouse Inquiry

Background

Androgen receptor (AR) is vital for the expression of the male phenotype and influences cellular proliferation and differentiation in target tissues, functioning as a ligand-activated transcription factor. The AR structure comprises the ligand binding domain (LBD), N-terminal domain (NTD), and DNA binding domain (DBD) with its primary functions in the nucleus. Deoxyribonucleic acid (DNA) serves as the essential polymer carrying genetic information for all organisms and is indispensable for all known forms of life. Creative Biolabs presents an anti-AR×anti-DNA bispecific antibody designed to enter prostate cancer cells, inhibiting androgen receptor function and tailored for prostate cancer therapy research.

Androgen and AR action. (Tan, et al., 2015) Fig.1 Scheme diagram of androgen and AR action.1

Reference

  1. Tan, M. H., et al. "Androgen receptor: structure, role in prostate cancer and drug discovery." Acta Pharmacologica Sinica 36.1 (2015): 3-23.
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