C5 & HRP Bispecific Antibodies

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Product List

CAT#	Product Name	Species Reactivity	BsAb Type	Target 1	Host Animal 1	Target 2	Host Animal 2	INQUIRY
T-BSDB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Tandem Diabody)	Human	Tandem Diabody	C5	Mouse	HRP	Mouse	Inquiry
SCIGG-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scIgG)	Human	Single chain IgGs	C5	Mouse	HRP	Mouse	Inquiry
FVTIG-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scFv4-Ig)	Human	scFv4-Ig	C5	Mouse	HRP	Mouse	Inquiry
BSSG-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scFv-IgG)	Human	scFv-IgG	C5	Mouse	HRP	Mouse	Inquiry
IGLFV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (IgG(L)-scFv)	Human	IgG-scFv	C5	Mouse	HRP	Mouse	Inquiry
BSGV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (IgG-Fv)	Human	IgG-Fv	C5	Mouse	HRP	Mouse	Inquiry
BSDG-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Fv-IgG)	Human	Fv-IgG	C5	Mouse	HRP	Mouse	Inquiry
BABFV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (F(ab')2-scFv2)	Human	F(ab')2-scFv2	C5	Mouse	HRP	Mouse	Inquiry
FABVC-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Fab-scFv-Fc)	Human	Fab-scFv/sdAb-Fc	C5	Mouse	HRP	Mouse	Inquiry
SCDBC-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scDiabody-CH3)	Human	scDiabody-CH3	C5	Mouse	HRP	Mouse	Inquiry
BSDBC-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Diabody-CH3)	Human	Diabody-CH3	C5	Mouse	HRP	Mouse	Inquiry
SCDBF-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scDiabody-Fc)	Human	scDiabody-Fc	C5	Mouse	HRP	Mouse	Inquiry
BSFVF-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Tandem scFv-Fc)	Human	Tandem scFv-Fc	C5	Mouse	HRP	Mouse	Inquiry
BSDBF-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Diabody-Fc)	Human	Diabody-Fc	C5	Mouse	HRP	Mouse	Inquiry
BSTF-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scFv-Fc-scFv)	Human	scFv-Fc-scFv	C5	Mouse	HRP	Mouse	Inquiry
BSCFV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scFv-Fc)	Human	scFv-Fc	C5	Mouse	HRP	Mouse	Inquiry
MNAB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Miniantibody)	Human	Miniantibody	C5	Mouse	HRP	Mouse	Inquiry
BSFC-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scFv-CH3)	Human	scFv-CH3	C5	Mouse	HRP	Mouse	Inquiry
BSCC-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (scFv-CH1/CL)	Human	scFv-CH1/CL	C5	Mouse	HRP	Mouse	Inquiry
BIBD-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Bibody)	Human	Bibody	C5	Mouse	HRP	Mouse	Inquiry
FABFV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Fab-Fv)	Human	Fab-Fv	C5	Mouse	HRP	Mouse	Inquiry
MiniB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Minibody)	Human	Minibody	C5	Mouse	HRP	Mouse	Inquiry
SCDB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Single-chain Diabody)	Human	Single-chain Diabody	C5	Mouse	HRP	Mouse	Inquiry
FABIG-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Fab-IgG)	Human	Fab-IgG	C5	Mouse	HRP	Mouse	Inquiry
TRIB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Fab-scFv-scFv)	Human	Fab-scFv-scFv	C5	Mouse	HRP	Mouse	Inquiry
BSIG-024	Anti-C5 x Anti-HRP Bispecific Antibody (IgG-IgG)	Human	IgG-IgG	C5	Mouse	HRP	Mouse	Inquiry
CROSSAB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (CrossMab)	Human	CrossMab	C5	Mouse	HRP	Mouse	Inquiry
IGFV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (IgG-scFv)	Human	IgG-scFv	C5	Mouse	HRP	Mouse	Inquiry
BSDB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Diabody)	Human	Diabody	C5	Mouse	HRP	Mouse	Inquiry
BSFAB-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Tandem Fab)	Human	Tandem Fab	C5	Mouse	HRP	Mouse	Inquiry
BSFV-024	Recombinant Anti-C5 x Anti-HRP Bispecific Antibody (Tandem scFv)	Human	Tandem scFv	C5	Mouse	HRP	Mouse	Inquiry
T-BSDB-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Tandem Diabody)		Tandem Diabody	biotin	Mouse	HRP	Mouse	Inquiry
SCIGG-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (scIgG)		Single chain IgGs	Biotin	Mouse	HRP	Mouse	Inquiry
FVTIG-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scFv4-Ig)		scFv4-Ig	biotin	Mouse	HRP	Mouse	Inquiry
BSSG-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scFv-IgG)		scFv-IgG	biotin	Mouse	HRP	Mouse	Inquiry
IGLFV-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (IgG(L)-scFv)		IgG-scFv	biotin	Mouse	HRP	Mouse	Inquiry
BSGV-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (IgG-Fv)		IgG-Fv	biotin	Mouse	HRP	Mouse	Inquiry
BSDG-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Fv-IgG)		Fv-IgG	biotin	Mouse	HRP	Mouse	Inquiry
BABFV-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (F(ab')2-scFv2)		F(ab')2-scFv2	biotin	Mouse	HRP	Mouse	Inquiry
FABVC-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Fab-scFv-Fc)		Fab-scFv/sdAb-Fc	biotin	Mouse	HRP	Mouse	Inquiry
SCDBC-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scDiabody-CH3)		scDiabody-CH3	biotin	Mouse	HRP	Mouse	Inquiry
BSDBC-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Diabody-CH3)		Diabody-CH3	biotin	Mouse	HRP	Mouse	Inquiry
SCDBF-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scDiabody-Fc)		scDiabody-Fc	biotin	Mouse	HRP	Mouse	Inquiry
BSFVF-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Tandem scFv-Fc)		Tandem scFv-Fc	biotin	Mouse	HRP	Mouse	Inquiry
BSDBF-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Diabody-Fc)		Diabody-Fc	biotin	Mouse	HRP	Mouse	Inquiry
BSTF-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scFv-Fc-scFv)		scFv-Fc-scFv	biotin	Mouse	HRP	Mouse	Inquiry
BSCFV-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scFv-Fc)		scFv-Fc	biotin	Mouse	HRP	Mouse	Inquiry
MNAB-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (Miniantibody)		Miniantibody	biotin	Mouse	HRP	Mouse	Inquiry
BSFC-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scFv-CH3)		scFv-CH3	biotin	Mouse	HRP	Mouse	Inquiry
BSCC-022	Recombinant Anti-biotin x Anti-HRP Bispecific Antibody (scFv-CH1/CL)		scFv-CH1/CL	biotin	Mouse	HRP	Mouse	Inquiry
BIBD-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Bibody)		Bibody	Biotin	Mouse	HRP	Mouse	Inquiry
FABFV-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Fab-Fv)		Fab-Fv	Biotin	Mouse	HRP	Mouse	Inquiry
MiniB-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Minibody)		Minibody	Biotin	Mouse	HRP	Mouse	Inquiry
SCDB-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Single-chain Diabody)		Single-chain Diabody	Biotin	Mouse	HRP	Mouse	Inquiry
FABIG-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Fab-IgG)		Fab-IgG	Biotin	Mouse	HRP	Mouse	Inquiry
TRIB-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Fab-scFv-scFv)		Fab-scFv-scFv	Biotin	Mouse	HRP	Mouse	Inquiry
BSIG-022	Anti-Biotin x Anti-HRP Bispecific Antibody (IgG-IgG)		IgG-IgG	Biotin	Mouse	HRP	Mouse	Inquiry
CROSSAB-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (CrossMab)		CrossMab	Biotin	Mouse	HRP	Mouse	Inquiry
IGFV-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (IgG-scFv)		IgG-scFv	Biotin	Mouse	HRP	Mouse	Inquiry
BSDB-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Diabody)		Diabody	Biotin	Mouse	HRP	Mouse	Inquiry
BSFAB-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Tandem Fab)		Tandem Fab	Biotin	Mouse	HRP	Mouse	Inquiry
BSFV-022	Recombinant Anti-Biotin x Anti-HRP Bispecific Antibody (Tandem scFv)		Tandem scFv	Biotin	Mouse	HRP	Mouse	Inquiry

Background

C5, a pivotal factor in the complement system, undergoes activation by C5 convertase, initiating spontaneous assembly of the late complement components to form the membrane attack complex. Comprising C5a and C5b, the latter transiently binds to C6, laying the foundation for the lytic complex. Horseradish peroxidase (HRP) can be linked to antibodies through periodate oxidation, disulfide bonds, glutaraldehyde, and other methods, producing colored or luminescent derivatives upon binding with a substrate, allowing quantification. On the basis of these, Creative Biolabs has developed an anti-C5×anti-HRP bispecific antibody for immunoassays targeting colon cancer, pancreatic cancer, and lung cancer.

Structure of C5 and HRP. (Fredslund, et al., 2008; Barnard, et al., 2012) Fig.1 Structure of C5 and HRP. Left: C5, right: HRP.^{1, 2}

References

Fredslund, Folmer, et al. "Structure of and influence of a tick complement inhibitor on human complement component 5." Nature Immunology 9.7 (2008): 753-760.
Barnard, Almero. The optimization of the extraction and purification of horseradish peroxidase from horseradish roots. Diss. Stellenbosch: Stellenbosch University, 2012.

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