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CD19 & CD28 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H215 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD19 Human CD28 Human Inquiry
T-BSDB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD19 Mouse CD28 Mouse Inquiry
SCIGG-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scIgG) Human Single chain IgGs CD19 Human CD28 Human Inquiry
SCIGG-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scIgG) Human Single chain IgGs CD19 Mouse CD28 Mouse Inquiry
FVTIG-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD19 Human CD28 Human Inquiry
FVTIG-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD19 Mouse CD28 Mouse Inquiry
BSSG-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD19 Human CD28 Human Inquiry
BSSG-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD19 Mouse CD28 Mouse Inquiry
IGLFV-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD19 Human CD28 Human Inquiry
IGLFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD19 Mouse CD28 Mouse Inquiry
BSGV-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD19 Human CD28 Human Inquiry
BSGV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD19 Mouse CD28 Mouse Inquiry
BSDG-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD19 Human CD28 Human Inquiry
BSDG-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD19 Mouse CD28 Mouse Inquiry
BABFV-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD19 Human CD28 Human Inquiry
BABFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD19 Mouse CD28 Mouse Inquiry
FABVC-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD19 Human CD28 Human Inquiry
FABVC-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD19 Mouse CD28 Mouse Inquiry
SCDBC-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD19 Human CD28 Human Inquiry
SCDBC-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD19 Mouse CD28 Mouse Inquiry
BSDBC-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD19 Human CD28 Human Inquiry
BSDBC-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD19 Mouse CD28 Mouse Inquiry
SCDBF-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD19 Human CD28 Human Inquiry
SCDBF-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD19 Mouse CD28 Mouse Inquiry
BSFVF-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD19 Human CD28 Human Inquiry
BSFVF-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD19 Mouse CD28 Mouse Inquiry
BSDBF-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD19 Human CD28 Human Inquiry
BSDBF-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD19 Mouse CD28 Mouse Inquiry
BSTF-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD19 Human CD28 Human Inquiry
BSTF-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD19 Mouse CD28 Mouse Inquiry
BSCFV-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD19 Human CD28 Human Inquiry
BSCFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD19 Mouse CD28 Mouse Inquiry
MNAB-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Miniantibody) Human Miniantibody CD19 Human CD28 Human Inquiry
MNAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Miniantibody) Human Miniantibody CD19 Mouse CD28 Mouse Inquiry
BSFC-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD19 Human CD28 Human Inquiry
BSFC-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD19 Mouse CD28 Mouse Inquiry
BSCC-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD19 Human CD28 Human Inquiry
BSCC-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD19 Mouse CD28 Mouse Inquiry
BIBD-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Bibody) Human Bibody CD19 Human CD28 Human Inquiry
BIBD-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Bibody) Human Bibody CD19 Mouse CD28 Mouse Inquiry
FABFV-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Human CD28 Human Inquiry
FABFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD19 Mouse CD28 Mouse Inquiry
MiniB-H217 Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (Minibody) Human Minibody CD19 Human CD28 Human Inquiry
MiniB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Minibody) Human Minibody CD19 Mouse CD28 Mouse Inquiry
SCTB-H115 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD19 Human CD28 Human Inquiry
SCDB-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 Human CD28 Human Inquiry
FABIG-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 Human CD28 Human Inquiry
TRIB-H217 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD19 Human CD28 Human Inquiry
BSIG-H215 Human Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Human CD28 Human Inquiry
CROSSAB-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD19 Human CD28 Human Inquiry
IGFV-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Human CD28 Human Inquiry
BSDB-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD19 Human CD28 Human Inquiry
BSFAB-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Human CD28 Human Inquiry
BSFV-H215 Recombinant Human Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Human CD28 Human Inquiry
SCTB-015 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD19 Mouse CD28 Mouse Inquiry
SCDB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 Mouse CD28 Mouse Inquiry
FABIG-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 Mouse CD28 Mouse Inquiry
TRIB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD19 Mouse CD28 Mouse Inquiry
BSIG-040 Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD28 Mouse Inquiry
CROSSAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD28 Mouse Inquiry
IGFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD28 Mouse Inquiry
BSDB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD28 Mouse Inquiry
BSFAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD28 Mouse Inquiry
BSFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD28 Mouse Inquiry
BSIG-055 Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD30 Mouse Inquiry
BSIG-054 Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD3 Mouse Inquiry
BSIG-050 Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Mouse CD28 Mouse Inquiry
BSIG-045 Anti-CD19 x Anti-CD89 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD89 Mouse Inquiry
BSIG-044 Anti-CD19 x Anti-CD64 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD64 Mouse Inquiry
BSIG-043 Anti-CD19 x Anti-CD59 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD59 Mouse Inquiry
BSIG-042 Anti-CD19 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD47 Mouse Inquiry
BSIG-041 Anti-CD19 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD3 Mouse Inquiry
BSIG-039 Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD22 Mouse Inquiry
CROSSAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CSPG4 Mouse Inquiry
CROSSAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse MUC1 Mouse Inquiry
CROSSAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse HN Mouse Inquiry
CROSSAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse FOLR1 Mouse Inquiry
CROSSAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse EPCAM Mouse Inquiry
CROSSAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse EGFR Mouse Inquiry
CROSSAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD44 Mouse Inquiry
CROSSAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD40 Mouse Inquiry
CROSSAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD30 Mouse Inquiry
CROSSAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD3 Mouse Inquiry
CROSSAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 Mouse CD28 Mouse Inquiry
CROSSAB-045 Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD89 Mouse Inquiry
CROSSAB-044 Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD64 Mouse Inquiry
CROSSAB-043 Recombinant Anti-CD19 x Anti-CD59 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD59 Mouse Inquiry
CROSSAB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD47 Mouse Inquiry
CROSSAB-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD3 Mouse Inquiry
CROSSAB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD22 Mouse Inquiry
IGFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CSPG4 Mouse Inquiry
IGFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse MUC1 Mouse Inquiry
IGFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse HN Mouse Inquiry
IGFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse FOLR1 Mouse Inquiry
IGFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse EPCAM Mouse Inquiry
IGFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse EGFR Mouse Inquiry
IGFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD44 Mouse Inquiry
IGFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD40 Mouse Inquiry
IGFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD30 Mouse Inquiry
IGFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD3 Mouse Inquiry
IGFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Mouse CD28 Mouse Inquiry
IGFV-045 Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD89 Mouse Inquiry
IGFV-044 Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD64 Mouse Inquiry
IGFV-043 Recombinant Anti-CD19 x Anti-CD59 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD59 Mouse Inquiry
IGFV-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD47 Mouse Inquiry
IGFV-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD3 Mouse Inquiry
IGFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD22 Mouse Inquiry
BSDB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CSPG4 Mouse Inquiry
BSDB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse MUC1 Mouse Inquiry
BSDB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Diabody) Human Diabody CD28 Mouse HN Mouse Inquiry
BSDB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse FOLR1 Mouse Inquiry
BSDB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Diabody) Human Diabody CD28 Mouse EPCAM Mouse Inquiry
BSDB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD28 Mouse EGFR Mouse Inquiry
BSDB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD44 Mouse Inquiry
BSDB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD40 Mouse Inquiry
BSDB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD30 Mouse Inquiry
BSDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD3 Mouse Inquiry
BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 Mouse CD28 Mouse Inquiry
BSDB-045 Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD89 Mouse Inquiry
BSDB-044 Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD64 Mouse Inquiry
BSDB-043 Recombinant Anti-CD19 x Anti-CD59 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD59 Mouse Inquiry
BSDB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD47 Mouse Inquiry
BSDB-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD3 Mouse Inquiry
BSDB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD22 Mouse Inquiry
BSFAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CSPG4 Mouse Inquiry
BSFAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse MUC1 Mouse Inquiry
BSFAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse HN Mouse Inquiry
BSFAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse FOLR1 Mouse Inquiry
BSFAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EPCAM Mouse Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EGFR Mouse Inquiry
BSFAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD44 Mouse Inquiry
BSFAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD40 Mouse Inquiry
BSFAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD30 Mouse Inquiry
BSFAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD3 Mouse Inquiry
BSFAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD28 Mouse Inquiry
BSFAB-045 Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD89 Mouse Inquiry
BSFAB-044 Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD64 Mouse Inquiry
BSFAB-043 Recombinant Anti-CD19 x Anti-CD59 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD59 Mouse Inquiry
BSFAB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD47 Mouse Inquiry
BSFAB-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD3 Mouse Inquiry
BSFAB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD22 Mouse Inquiry
BSFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CSPG4 Mouse Inquiry
BSFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse MUC1 Mouse Inquiry
BSFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse HN Mouse Inquiry
BSFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse FOLR1 Mouse Inquiry
BSFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EPCAM Mouse Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EGFR Mouse Inquiry
BSFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD44 Mouse Inquiry
BSFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD40 Mouse Inquiry
BSFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD30 Mouse Inquiry
BSFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD3 Mouse Inquiry
BSFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD28 Mouse Inquiry
BSFV-045 Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD89 Mouse Inquiry
BSFV-044 Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD64 Mouse Inquiry
BSFV-043 Recombinant Anti-CD19 x Anti-CD59 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD59 Mouse Inquiry
BSFV-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD47 Mouse Inquiry
BSFV-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD3 Mouse Inquiry
BSFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD22 Mouse Inquiry

Background

CD19 (cluster of differentiation 19) and CD28 (cluster of differentiation 28) are cell surface proteins that play crucial roles in the immune system. CD19, a B cell co-receptor, can enhance B cell activation, differentiation, and antibody production, thereby contributing to adaptive immune responses against pathogens. CD28 is a co-stimulatory signal present on T cells which is vital for T cell activation. It interacts with CD80/86 molecules on antigen-presenting cells, promoting cytokine production and T cell proliferation. This signaling pathway is vital for effective T cell responses. The anti-CD19/CD28 bispecific antibody (BsAb) can be constructed as a potential therapeutic approach for immunotherapy. This BsAb functions by activating T cells through CD28 signaling and directing their cytotoxic activity towards CD19-expressing B cells. This strategy can effectively eliminate cancerous B cells by targeting CD19, which is often overexpressed in B cell malignancies.

Fig.1 Functions of CD19 and CD28. (Li, et al., 2017; Alegre, Kenneth and Craig, 2001) Fig.1 The functional mechanisms of CD19 and CD28.1,2

References

  1. Li, Xinchen, et al. "CD19, from bench to bedside." Immunology Letters 183 (2017): 86-95.
  2. Alegre, Maria-Luisa, Kenneth A. Frauwirth, and Craig B. Thompson. "T-cell regulation by CD28 and CTLA-4." Nature Reviews Immunology 1.3 (2001): 220-228.
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