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CD20 & CD28 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H225 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD20 Human CD28 Human Inquiry
T-BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD20 Mouse CD28 Mouse Inquiry
SCIGG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scIgG) Human Single chain IgGs CD20 Human CD28 Human Inquiry
FABVC-363 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-sdAb-Fc) Human Fab-scFv/sdAb-Fc CD20 Mouse CD28 llama Inquiry
BSSG-363 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (sdAb-IgG) Human sdAb-IgG CD20 Mouse CD28 llama Inquiry
HCAB-008 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (sdAb-Fc-sdAb) Human sdAb-Fc-sdAb CD20 llama CD28 llama Inquiry
BIBD-363 Recombinant Anti-CD20 x Anti-CD28 VHH BispecificAntibody (Bibody) Human Bibody CD20 Mouse CD28 llama Inquiry
IGVHH-008 Recombinant Anti-CD20 x Anti-CD28 sdAb Bispecific Antibody (IgG-sdAb) Human IgG-sdAb CD20 Mouse CD28 llama Inquiry
BIVHH-007 Recombinant Anti-CD20 sdAb x Anti-CD28 sdAb Bispecific Antibody (Bi-sdAb) Human Bi-sdAb CD20 llama CD28 llama Inquiry
SCIGG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scIgG) Human Single chain IgGs CD20 Mouse CD28 Mouse Inquiry
FVTIG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD20 Human CD28 Human Inquiry
FVTIG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD20 Mouse CD28 Mouse Inquiry
BSSG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD20 Human CD28 Human Inquiry
BSSG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD20 Mouse CD28 Mouse Inquiry
IGLFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD20 Human CD28 Human Inquiry
IGLFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD20 Mouse CD28 Mouse Inquiry
BSGV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD20 Mouse CD28 Mouse Inquiry
BSGV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD20 Mouse CD28 Mouse Inquiry
BSDG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD20 Human CD28 Human Inquiry
BSDG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD20 Mouse CD28 Mouse Inquiry
BABFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD20 Human CD28 Human Inquiry
BABFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD20 Mouse CD28 Mouse Inquiry
FABVC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD20 Human CD28 Human Inquiry
FABVC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD20 Mouse CD28 Mouse Inquiry
SCDBC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD20 Human CD28 Human Inquiry
SCDBC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD20 Mouse CD28 Mouse Inquiry
BSDBC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD20 Human CD28 Human Inquiry
BSDBC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD20 Mouse CD28 Mouse Inquiry
SCDBF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD20 Human CD28 Human Inquiry
SCDBF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD20 Mouse CD28 Mouse Inquiry
BSFVF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD20 Human CD28 Human Inquiry
BSFVF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD20 Mouse CD28 Mouse Inquiry
BSDBF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD20 Human CD28 Human Inquiry
BSDBF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD20 Mouse CD28 Mouse Inquiry
BSTF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD20 Mouse CD28 Mouse Inquiry
BSTF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD20 Mouse CD28 Mouse Inquiry
BSCFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD20 Mouse CD28 Mouse Inquiry
BSCFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD20 Mouse CD28 Mouse Inquiry
MNAB-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Miniantibody) Human Miniantibody CD20 Mouse CD28 Mouse Inquiry
MNAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Miniantibody) Human Miniantibody CD20 Mouse CD28 Mouse Inquiry
BSFC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD20 Mouse CD28 Mouse Inquiry
BSFC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD20 Mouse CD28 Mouse Inquiry
BSCC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD20 Mouse CD28 Mouse Inquiry
BSCC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD20 Mouse CD28 Mouse Inquiry
BIBD-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Bibody) Human Bibody CD20 Mouse CD28 Mouse Inquiry
BIBD-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Bibody) Human Bibody CD20 Mouse CD28 Mouse Inquiry
FABFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 Human CD28 Human Inquiry
FABFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 Mouse CD28 Mouse Inquiry
MiniB-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Minibody) Human Minibody CD20 Human CD28 Human Inquiry
MiniB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Minibody) Human Minibody CD20 Mouse CD28 Mouse Inquiry
SCTB-H123 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 Human CD28 Human Inquiry
SCDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 Human CD28 Human Inquiry
FABIG-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 Human CD28 Human Inquiry
TRIB-H227 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Human CD28 Human Inquiry
BSIG-H225 Human Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Human CD28 Human Inquiry
CROSSAB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 Human CD28 Human Inquiry
IGFV-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Human CD28 Human Inquiry
BSDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 Human CD28 Human Inquiry
BSFAB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Human CD28 Human Inquiry
BSFV-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Human CD28 Human Inquiry
SCTB-024 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 Mouse CD28 Mouse Inquiry
SCDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 Mouse CD28 Mouse Inquiry
FABIG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 Mouse CD28 Mouse Inquiry
TRIB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Mouse CD28 Mouse Inquiry
BSIG-050 Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Mouse CD28 Mouse Inquiry
CROSSAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 Mouse CD28 Mouse Inquiry
IGFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Mouse CD28 Mouse Inquiry
BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 Mouse CD28 Mouse Inquiry
BSFAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD28 Mouse Inquiry
BSFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD28 Mouse Inquiry
TRIB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse EGFR Mouse Inquiry
TRIB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse CD44 Mouse Inquiry
TRIB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse CD40 Mouse Inquiry
TRIB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse CD30 Mouse Inquiry
TRIB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse CD3 Mouse Inquiry
TRIB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Mouse CD47 Mouse Inquiry
TRIB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Mouse CD3 Mouse Inquiry
TRIB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Mouse CD22 Mouse Inquiry
TRIB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD19 Mouse CD28 Mouse Inquiry
BSIG-063 Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CSPG4 Mouse Inquiry
BSIG-062 Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse MUC1 Mouse Inquiry
BSIG-061 Anti-CD28 x Anti-HN Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse HN Mouse Inquiry
BSIG-060 Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse FOLR1 Mouse Inquiry
BSIG-059 Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse EPCAM Mouse Inquiry
BSIG-058 Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse EGFR Mouse Inquiry
BSIG-057 Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD44 Mouse Inquiry
BSIG-056 Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD40 Mouse Inquiry
BSIG-055 Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD30 Mouse Inquiry
BSIG-054 Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD3 Mouse Inquiry
BSIG-052 Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Mouse CD47 Mouse Inquiry
BSIG-051 Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Mouse CD3 Mouse Inquiry
BSIG-049 Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Mouse CD22 Mouse Inquiry
BSIG-040 Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD28 Mouse Inquiry
CROSSAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CSPG4 Mouse Inquiry
CROSSAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse MUC1 Mouse Inquiry
CROSSAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse HN Mouse Inquiry
CROSSAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse FOLR1 Mouse Inquiry
CROSSAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse EPCAM Mouse Inquiry
CROSSAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse EGFR Mouse Inquiry
CROSSAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD44 Mouse Inquiry
CROSSAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD40 Mouse Inquiry
CROSSAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD30 Mouse Inquiry
CROSSAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD3 Mouse Inquiry
CROSSAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD20 Mouse CD47 Mouse Inquiry
CROSSAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD20 Mouse CD3 Mouse Inquiry
CROSSAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 Mouse CD22 Mouse Inquiry
CROSSAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD28 Mouse Inquiry
IGFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CSPG4 Mouse Inquiry
IGFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse MUC1 Mouse Inquiry
IGFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse HN Mouse Inquiry
IGFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse FOLR1 Mouse Inquiry
IGFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse EPCAM Mouse Inquiry
IGFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse EGFR Mouse Inquiry
IGFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD44 Mouse Inquiry
IGFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD40 Mouse Inquiry
IGFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD30 Mouse Inquiry
IGFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD3 Mouse Inquiry
IGFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Mouse CD47 Mouse Inquiry
IGFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Mouse CD3 Mouse Inquiry
IGFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Mouse CD22 Mouse Inquiry
IGFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD28 Mouse Inquiry
BSDB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CSPG4 Mouse Inquiry
BSDB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse MUC1 Mouse Inquiry
BSDB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Diabody) Human Diabody CD28 Mouse HN Mouse Inquiry
BSDB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse FOLR1 Mouse Inquiry
BSDB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Diabody) Human Diabody CD28 Mouse EPCAM Mouse Inquiry
BSDB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD28 Mouse EGFR Mouse Inquiry
BSDB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD44 Mouse Inquiry
BSDB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD40 Mouse Inquiry
BSDB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD30 Mouse Inquiry
BSDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD3 Mouse Inquiry
BSDB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD20 Mouse CD47 Mouse Inquiry
BSDB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD20 Mouse CD3 Mouse Inquiry
BSDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 Mouse CD22 Mouse Inquiry
BSDB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD28 Mouse Inquiry
BSFAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CSPG4 Mouse Inquiry
BSFAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse MUC1 Mouse Inquiry
BSFAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse HN Mouse Inquiry
BSFAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse FOLR1 Mouse Inquiry
BSFAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EPCAM Mouse Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EGFR Mouse Inquiry
BSFAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD44 Mouse Inquiry
BSFAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD40 Mouse Inquiry
BSFAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD30 Mouse Inquiry
BSFAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD3 Mouse Inquiry
BSFAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD47 Mouse Inquiry
BSFAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD3 Mouse Inquiry
BSFAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD22 Mouse Inquiry
BSFAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD28 Mouse Inquiry
BSFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CSPG4 Mouse Inquiry
BSFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse MUC1 Mouse Inquiry
BSFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse HN Mouse Inquiry
BSFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse FOLR1 Mouse Inquiry
BSFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EPCAM Mouse Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EGFR Mouse Inquiry
BSFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD44 Mouse Inquiry
BSFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD40 Mouse Inquiry
BSFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD30 Mouse Inquiry
BSFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD3 Mouse Inquiry
BSFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD47 Mouse Inquiry
BSFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD3 Mouse Inquiry
BSFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD22 Mouse Inquiry
BSFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD28 Mouse Inquiry

Background

CD20 is a membrane-embedded surface molecule found largely on B cells, regulating B cell activation and differentiation. CD28 is primarily found on T cells and serves as an important costimulatory receptor in the activation of naive T cells. The anti-CD20×anti-CD28 bispecific antibody (BsAb) can simultaneously bind to both proteins that bring T cells close to B cells expressing the CD20 antigen, triggering T cell activation and subsequent elimination of B cells. This approach has the potential to improve the efficacy of immunotherapy for B cell malignancies, particularly when CD20-targeted monoclonal antibody therapy alone is insufficient. This strategy is being investigated in preclinical and clinical studies for the treatment of B-cell lineage leukemia and lymphoma.

Fig.1 Functional mechanisms of CD20 and CD28. (Bagacean, et al., 2016; Rangel-Sosa, Estuardo and Augusto, 2017) Fig.1 Functions of CD20 and CD28.1,2

References

  1. Bagacean, Cristina, et al. "Anti-CD20 monoclonal antibodies in chronic lymphocytic leukemia: from uncertainties to promises." Immunotherapy 8.5 (2016): 569-581.
  2. Rangel-Sosa, Martha Montserrat, Estuardo Aguilar-Córdova, and Augusto Rojas-Martínez. "Immunotherapy and gene therapy as novel treatments for cancer." Colombia Médica 48.3 (2017): 138-147.
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