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CD20 & CD28 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Diabody) Human CD20 CD28 Inquiry
T-BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Diabody) Human CD20 CD28 Inquiry
SCIGG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scIgG) Human Single chain IgGs CD20 CD28 Inquiry
FABVC-363 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-VHH-Fc) Human Fab-Fc Fusion Proteins CD20 CD28 Inquiry
BSSG-363 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (VHH-IgG) Human Appended IgGs CD20 CD28 Inquiry
HCAB-008 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (VHH-Fc-VHH) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BIBD-363 Recombinant Anti-CD20 x Anti-CD28 VHH BispecificAntibody (Bibody) Human Bibody CD20 CD28 Inquiry
IGVHH-008 Recombinant Anti-CD20 x Anti-CD28 VHH BispecificAntibody (IgG-VHH) Human Appended IgGs CD20 CD28 Inquiry
BIVHH-007 Recombinant Anti-CD20 VHH x Anti-CD28 VHH BispecificAntibody (Bi-sdAb) Human Bi-sdAb CD20 CD28 Inquiry
SCIGG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scIgG) Human Single chain IgGs CD20 CD28 Inquiry
FVTIG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD20 CD28 Inquiry
FVTIG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD20 CD28 Inquiry
BSSG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD20 CD28 Inquiry
BSSG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD20 CD28 Inquiry
IGLFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD20 CD28 Inquiry
IGLFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD20 CD28 Inquiry
BSGV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD20 CD28 Inquiry
BSGV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD20 CD28 Inquiry
BSDG-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD20 CD28 Inquiry
BSDG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD20 CD28 Inquiry
BABFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD20 CD28 Inquiry
BABFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD20 CD28 Inquiry
FABVC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD20 CD28 Inquiry
FABVC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD20 CD28 Inquiry
SCDBC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
SCDBC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSDBC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSDBC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
SCDBF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
SCDBF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSFVF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSFVF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSDBF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSDBF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD28 Inquiry
BSTF-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSTF-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSCFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSCFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
MNAB-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
MNAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSFC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSFC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSCC-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BSCC-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD20 CD28 Inquiry
BIBD-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Bibody) Human Bibody CD20 CD28 Inquiry
BIBD-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Bibody) Human Bibody CD20 CD28 Inquiry
FABFV-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 CD28 Inquiry
FABFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 CD28 Inquiry
MiniB-H227 Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (Minibody) Human Minibody CD20 CD28 Inquiry
MiniB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Minibody) Human Minibody CD20 CD28 Inquiry
SCTB-H123 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD28 Inquiry
SCDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD28 Inquiry
FABIG-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD28 Inquiry
TRIB-H227 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD28 Inquiry
BSIG-H225 Human Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD28 Inquiry
CROSSAB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD28 Inquiry
IGFV-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD28 Inquiry
BSDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 CD28 Inquiry
BSFAB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD28 Inquiry
BSFV-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD28 Inquiry
SCTB-024 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD28 Inquiry
SCDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD28 Inquiry
FABIG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD28 Inquiry
TRIB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD28 Inquiry
BSIG-050 Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD28 Inquiry
CROSSAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD28 Inquiry
IGFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD28 Inquiry
BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 CD28 Inquiry
BSFAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD28 Inquiry
BSFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD28 Inquiry
TRIB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Triple Body) Human Triple Body CD28 EGFR Inquiry
TRIB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD44 Inquiry
TRIB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD40 Inquiry
TRIB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD30 Inquiry
TRIB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Triple Body) Human Triple Body CD28 CD3 Inquiry
TRIB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD47 Inquiry
TRIB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD3 Inquiry
TRIB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD22 Inquiry
TRIB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD19 CD28 Inquiry
BSIG-063 Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CSPG4 Inquiry
BSIG-062 Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 MUC1 Inquiry
BSIG-061 Anti-CD28 x Anti-HN Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 HN Inquiry
BSIG-060 Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 FOLR1 Inquiry
BSIG-059 Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 EPCAM Inquiry
BSIG-058 Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 EGFR Inquiry
BSIG-057 Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD44 Inquiry
BSIG-056 Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD40 Inquiry
BSIG-055 Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD30 Inquiry
BSIG-054 Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 CD3 Inquiry
BSIG-052 Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD47 Inquiry
BSIG-051 Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD3 Inquiry
BSIG-049 Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD22 Inquiry
BSIG-040 Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 CD28 Inquiry
CROSSAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (CrossMab) Human CrossMab CD28 CSPG4 Inquiry
CROSSAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (CrossMab) Human CrossMab CD28 MUC1 Inquiry
CROSSAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (CrossMab) Human CrossMab CD28 HN Inquiry
CROSSAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (CrossMab) Human CrossMab CD28 FOLR1 Inquiry
CROSSAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (CrossMab) Human CrossMab CD28 EPCAM Inquiry
CROSSAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD28 EGFR Inquiry
CROSSAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD44 Inquiry
CROSSAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD40 Inquiry
CROSSAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD30 Inquiry
CROSSAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD28 CD3 Inquiry
CROSSAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD47 Inquiry
CROSSAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD3 Inquiry
CROSSAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD22 Inquiry
CROSSAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD19 CD28 Inquiry
IGFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CSPG4 Inquiry
IGFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 MUC1 Inquiry
IGFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 HN Inquiry
IGFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 FOLR1 Inquiry
IGFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 EPCAM Inquiry
IGFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 EGFR Inquiry
IGFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD44 Inquiry
IGFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD40 Inquiry
IGFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD30 Inquiry
IGFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 CD3 Inquiry
IGFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD47 Inquiry
IGFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD3 Inquiry
IGFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD22 Inquiry
IGFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 CD28 Inquiry
BSDB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Diabody) Human Diabody CD28 CSPG4 Inquiry
BSDB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Diabody) Human Diabody CD28 MUC1 Inquiry
BSDB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Diabody) Human Diabody CD28 HN Inquiry
BSDB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Diabody) Human Diabody CD28 FOLR1 Inquiry
BSDB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Diabody) Human Diabody CD28 EPCAM Inquiry
BSDB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD28 EGFR Inquiry
BSDB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Diabody) Human Diabody CD28 CD44 Inquiry
BSDB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Diabody) Human Diabody CD28 CD40 Inquiry
BSDB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD28 CD30 Inquiry
BSDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD28 CD3 Inquiry
BSDB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD20 CD47 Inquiry
BSDB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD20 CD3 Inquiry
BSDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 CD22 Inquiry
BSDB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD19 CD28 Inquiry
BSFAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CSPG4 Inquiry
BSFAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 MUC1 Inquiry
BSFAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 HN Inquiry
BSFAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 FOLR1 Inquiry
BSFAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 EPCAM Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 EGFR Inquiry
BSFAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD44 Inquiry
BSFAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD40 Inquiry
BSFAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD30 Inquiry
BSFAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 CD3 Inquiry
BSFAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD47 Inquiry
BSFAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD3 Inquiry
BSFAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD22 Inquiry
BSFAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 CD28 Inquiry
BSFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CSPG4 Inquiry
BSFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 MUC1 Inquiry
BSFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 HN Inquiry
BSFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 FOLR1 Inquiry
BSFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 EPCAM Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 EGFR Inquiry
BSFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD44 Inquiry
BSFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD40 Inquiry
BSFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD30 Inquiry
BSFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 CD3 Inquiry
BSFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD47 Inquiry
BSFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD3 Inquiry
BSFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD22 Inquiry
BSFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 CD28 Inquiry

Background

CD20 is a membrane-embedded surface molecule found largely on B cells, regulating B cell activation and differentiation. CD28 is primarily found on T cells and serves as an important costimulatory receptor in the activation of naive T cells. The anti-CD20×anti-CD28 bispecific antibody (BsAb) can simultaneously bind to both proteins that bring T cells close to B cells expressing the CD20 antigen, triggering T cell activation and subsequent elimination of B cells. This approach has the potential to improve the efficacy of immunotherapy for B cell malignancies, particularly when CD20-targeted monoclonal antibody therapy alone is insufficient. This strategy is being investigated in preclinical and clinical studies for the treatment of B-cell lineage leukemia and lymphoma.

Fig.1 Functional mechanisms of CD20 and CD28. (Bagacean, et al., 2016; Rangel-Sosa, Estuardo and Augusto, 2017) Fig.1 Functions of CD20 and CD28.1,2

References

  1. Bagacean, Cristina, et al. "Anti-CD20 monoclonal antibodies in chronic lymphocytic leukemia: from uncertainties to promises." Immunotherapy 8.5 (2016): 569-581.
  2. Rangel-Sosa, Martha Montserrat, Estuardo Aguilar-Córdova, and Augusto Rojas-Martínez. "Immunotherapy and gene therapy as novel treatments for cancer." Colombia Médica 48.3 (2017): 138-147.
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