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CD20 & CD47 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem Diabody) Human CD20 CD47 Inquiry
T-BSDB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem Diabody) Human CD20 CD47 Inquiry
SCIGG-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scIgG) Human Single chain IgGs CD20 CD47 Inquiry
FABVC-365 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-VHH-Fc) Human Fab-Fc Fusion Proteins CD20 CD47 Inquiry
BSSG-365 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (VHH-IgG) Human Appended IgGs CD20 CD47 Inquiry
HCAB-010 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (VHH-Fc-VHH) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BIBD-365 Recombinant Anti-CD20 x Anti-CD47 VHH BispecificAntibody (Bibody) Human Bibody CD20 CD47 Inquiry
IGVHH-010 Recombinant Anti-CD20 x Anti-CD47 VHH BispecificAntibody (IgG-VHH) Human Appended IgGs CD20 CD47 Inquiry
BIVHH-010 Recombinant Anti-CD20 VHH x Anti-CD47 VHH BispecificAntibody (Bi-sdAb) Human Bi-sdAb CD20 CD47 Inquiry
SCIGG-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scIgG) Human Single chain IgGs CD20 CD47 Inquiry
FVTIG-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD20 CD47 Inquiry
FVTIG-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD20 CD47 Inquiry
BSSG-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD20 CD47 Inquiry
BSSG-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD20 CD47 Inquiry
IGLFV-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD20 CD47 Inquiry
IGLFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD20 CD47 Inquiry
BSGV-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD20 CD47 Inquiry
BSGV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD20 CD47 Inquiry
BSDG-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD20 CD47 Inquiry
BSDG-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD20 CD47 Inquiry
BABFV-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD20 CD47 Inquiry
BABFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD20 CD47 Inquiry
FABVC-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD20 CD47 Inquiry
FABVC-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD20 CD47 Inquiry
SCDBC-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
SCDBC-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSDBC-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSDBC-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
SCDBF-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
SCDBF-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSFVF-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSFVF-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSDBF-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSDBF-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD20 CD47 Inquiry
BSTF-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSTF-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSCFV-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSCFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
MNAB-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
MNAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSFC-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSFC-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSCC-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BSCC-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD20 CD47 Inquiry
BIBD-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Bibody) Human Bibody CD20 CD47 Inquiry
BIBD-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Bibody) Human Bibody CD20 CD47 Inquiry
FABFV-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 CD47 Inquiry
FABFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD20 CD47 Inquiry
MiniB-H229 Recombinant Human Anti-CD20 x Human Anti-CD47 Bispecific Antibody (Minibody) Human Minibody CD20 CD47 Inquiry
MiniB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Minibody) Human Minibody CD20 CD47 Inquiry
SCTB-H125 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD47 Inquiry
SCDB-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD47 Inquiry
FABIG-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD47 Inquiry
TRIB-H229 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD47 Inquiry
BSIG-H227 Human Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD47 Inquiry
CROSSAB-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD47 Inquiry
IGFV-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD47 Inquiry
BSDB-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD20 CD47 Inquiry
BSFAB-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD47 Inquiry
BSFV-H227 Recombinant Human Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD47 Inquiry
SCTB-026 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD47 Inquiry
SCDB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD47 Inquiry
FABIG-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD47 Inquiry
TRIB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD47 Inquiry
BSIG-052 Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD47 Inquiry
CROSSAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD47 Inquiry
IGFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD47 Inquiry
BSDB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD20 CD47 Inquiry
BSFAB-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD47 Inquiry
BSFV-052 Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD47 Inquiry
BSFV-ABR004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-PAP022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
SCTB-H124 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD3 Inquiry
SCTB-H123 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD28 Inquiry
SCTB-H117 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD19 CD47 Inquiry
SCDB-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD3 Inquiry
SCDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD28 Inquiry
SCDB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD22 Inquiry
SCDB-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 CD47 Inquiry
FABIG-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD3 Inquiry
FABIG-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD28 Inquiry
FABIG-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD22 Inquiry
FABIG-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 CD47 Inquiry
TRIB-H228 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD3 Inquiry
TRIB-H227 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD28 Inquiry
TRIB-H226 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD22 Inquiry
TRIB-H219 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Triple Body) Human Triple Body CD19 CD47 Inquiry
BSIG-H226 Human Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD3 Inquiry
BSIG-H225 Human Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD28 Inquiry
BSIG-H224 Human Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD22 Inquiry
BSIG-H217 Human Anti-CD19 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 CD47 Inquiry
CROSSAB-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD3 Inquiry
CROSSAB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD28 Inquiry
CROSSAB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD22 Inquiry
CROSSAB-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD19 CD47 Inquiry
IGFV-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD3 Inquiry
IGFV-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD28 Inquiry
IGFV-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD22 Inquiry
IGFV-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 CD47 Inquiry
BSDB-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD20 CD3 Inquiry
BSDB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 CD28 Inquiry
BSDB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 CD22 Inquiry
BSDB-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD19 CD47 Inquiry
BSFAB-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD3 Inquiry
BSFAB-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD28 Inquiry
BSFAB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD22 Inquiry
BSFAB-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 CD47 Inquiry
BSFV-H226 Recombinant Human Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD3 Inquiry
BSFV-H225 Recombinant Human Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD28 Inquiry
BSFV-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD22 Inquiry
BSFV-H217 Recombinant Human Anti-CD19 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 CD47 Inquiry
SCTB-025 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD3 Inquiry
SCTB-024 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD20 CD28 Inquiry
SCTB-017 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD19 CD47 Inquiry
SCDB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD3 Inquiry
SCDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD28 Inquiry
SCDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD22 Inquiry
SCDB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 CD47 Inquiry
FABIG-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD3 Inquiry
FABIG-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD28 Inquiry
FABIG-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD22 Inquiry
FABIG-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 CD47 Inquiry
TRIB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD3 Inquiry
TRIB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD28 Inquiry
TRIB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD22 Inquiry
TRIB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Triple Body) Human Triple Body CD19 CD47 Inquiry
BSIG-051 Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD3 Inquiry
BSIG-050 Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD28 Inquiry
BSIG-049 Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD22 Inquiry
BSIG-042 Anti-CD19 x Anti-CD47 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 CD47 Inquiry
CROSSAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD3 Inquiry
CROSSAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD28 Inquiry
CROSSAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD22 Inquiry
CROSSAB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (CrossMab) Human CrossMab CD19 CD47 Inquiry
IGFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD3 Inquiry
IGFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD28 Inquiry
IGFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD22 Inquiry
IGFV-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 CD47 Inquiry
BSDB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD20 CD3 Inquiry
BSDB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Diabody) Human Diabody CD20 CD28 Inquiry
BSDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 CD22 Inquiry
BSDB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Diabody) Human Diabody CD19 CD47 Inquiry
BSFAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD3 Inquiry
BSFAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD28 Inquiry
BSFAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD22 Inquiry
BSFAB-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 CD47 Inquiry
BSFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD3 Inquiry
BSFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD28 Inquiry
BSFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD22 Inquiry
BSFV-042 Recombinant Anti-CD19 x Anti-CD47 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 CD47 Inquiry

Background

CD20 is primarily expressed in B-cells and plays a crucial role in their development and function. CD20 is a target in various B-cell malignancies, making it an attractive therapeutic target. CD47 is a "don't eat me" signal produced on the surface of healthy cells that blocks macrophages from phagocytosing healthy cells. However, cancer cells often exploit this protective signal to evade immune surveillance. The CD20/CD47 bispecific antibody (BsAb) has a distinctive potential for CD20-directed suppression of CD47-SIRP "don't eat me" signaling, enabling the immune system to recognize and eliminate CD20-expressing B-cells, including cancerous cells. Besides, this BsAb can block the CD47/SIRPα interaction by binding to CD20, which reduces off-target phagocytosis and enhances safety and anti-tumor activity in vivo. This novel approach holds promise for treating B-cell malignancies, additionally, There may be potential applications of CD20/CD47 BsAb in autoimmune diseases and other conditions characterized by abnormal B-cell activity.

Fig.1 Mechanism of CD20/CD47 BsAb. (Yu, Yongping and Wenzhi, 2020) Fig.1 Working model of CD20/CD47 BsAb.1

Reference

  1. Yu, Jifeng, Yongping Song, and Wenzhi Tian. "How to select IgG subclasses in developing anti-tumor therapeutic antibodies." Journal of Hematology & Oncology 13 (2020): 1-10.
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