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CD22 & saporin
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Tandem Diabody) Human CD22 saporin Inquiry
SCIGG-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scIgG) Human Single chain IgGs CD22 saporin Inquiry
FVTIG-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD22 saporin Inquiry
BSSG-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-IgG) Human Appended IgGs CD22 saporin Inquiry
IGLFV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD22 saporin Inquiry
BSGV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (IgG-Fv) Human IgG-Fv CD22 saporin Inquiry
BSDG-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Fv-IgG) Human Appended IgGs CD22 saporin Inquiry
BABFV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD22 saporin Inquiry
FABVC-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD22 saporin Inquiry
SCDBC-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD22 saporin Inquiry
BSDBC-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD22 saporin Inquiry
SCDBF-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD22 saporin Inquiry
BSFVF-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD22 saporin Inquiry
BSDBF-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD22 saporin Inquiry
BSTF-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD22 saporin Inquiry
BSCFV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-Fc) Human scFv-Fc CD22 saporin Inquiry
MNAB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Miniantibody) Human Miniantibody CD22 saporin Inquiry
BSFC-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD22 saporin Inquiry
BSCC-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD22 saporin Inquiry
BIBD-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Bibody) Human Bibody CD22 saporin Inquiry
FABFV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Fab-Fv) Human Fab-Fv CD22 saporin Inquiry
MiniB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Minibody) Human Minibody CD22 saporin Inquiry
SCDB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD22 saporin Inquiry
FABIG-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD22 saporin Inquiry
TRIB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Triple Body) Human Triple Body CD22 saporin Inquiry
BSIG-053 Anti-CD22 x Anti-saporin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD22 saporin Inquiry
CROSSAB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (CrossMab) Human CrossMab CD22 saporin Inquiry
IGFV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD22 saporin Inquiry
BSDB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Diabody) Human Diabody CD22 saporin Inquiry
BSFAB-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD22 saporin Inquiry
BSFV-053 Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD22 saporin Inquiry
BSFAB-PE004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFAB-PE003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFAB-DT022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFAB-DT021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFAB-DT004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFAB-DT003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-SAR022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-SAR021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-SAR004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-SAR003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-NGB022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-NGB021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-NGB004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-NGB003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-MEL022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-MEL021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-MEL004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-MEL003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-BGN022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-BGN021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-BGN004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-BGN003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-ABR022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-ABR021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-ABR004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-ABR003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-PAP022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-PAP021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
SCDB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD22 Inquiry
SCDB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 CD22 Inquiry
FABIG-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD22 Inquiry
FABIG-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 CD22 Inquiry
TRIB-H226 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD22 Inquiry
TRIB-H216 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD19 CD22 Inquiry
BSIG-H224 Human Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD22 Inquiry
BSIG-H214 Human Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 CD22 Inquiry
CROSSAB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD22 Inquiry
CROSSAB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD19 CD22 Inquiry
IGFV-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD22 Inquiry
IGFV-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 CD22 Inquiry
BSDB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 CD22 Inquiry
BSDB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD19 CD22 Inquiry
BSFAB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD22 Inquiry
BSFAB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 CD22 Inquiry
BSFV-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD22 Inquiry
BSFV-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 CD22 Inquiry
SCDB-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD7 saporin Inquiry
SCDB-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD38 saporin Inquiry
SCDB-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD37 saporin Inquiry
SCDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 CD22 Inquiry
SCDB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 CD22 Inquiry
FABIG-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD7 saporin Inquiry
FABIG-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD38 saporin Inquiry
FABIG-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD37 saporin Inquiry
FABIG-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 CD22 Inquiry
FABIG-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 CD22 Inquiry
TRIB-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Triple Body) Human Triple Body CD7 saporin Inquiry
TRIB-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Triple Body) Human Triple Body CD38 saporin Inquiry
TRIB-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Triple Body) Human Triple Body CD37 saporin Inquiry
TRIB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD20 CD22 Inquiry
TRIB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Triple Body) Human Triple Body CD19 CD22 Inquiry
BSIG-130 Anti-CD7 x Anti-saporin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD7 saporin Inquiry
BSIG-120 Anti-CD38 x Anti-saporin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD38 saporin Inquiry
BSIG-118 Anti-CD37 x Anti-saporin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD37 saporin Inquiry
BSIG-049 Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 CD22 Inquiry
BSIG-039 Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 CD22 Inquiry
CROSSAB-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (CrossMab) Human CrossMab CD7 saporin Inquiry
CROSSAB-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (CrossMab) Human CrossMab CD38 saporin Inquiry
CROSSAB-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (CrossMab) Human CrossMab CD37 saporin Inquiry
CROSSAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 CD22 Inquiry
CROSSAB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD19 CD22 Inquiry
IGFV-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD7 saporin Inquiry
IGFV-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD38 saporin Inquiry
IGFV-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD37 saporin Inquiry
IGFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 CD22 Inquiry
IGFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 CD22 Inquiry
BSDB-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Diabody) Human Diabody CD7 saporin Inquiry
BSDB-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody) Human Diabody CD38 saporin Inquiry
BSDB-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Diabody) Human Diabody CD37 saporin Inquiry
BSDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 CD22 Inquiry
BSDB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD19 CD22 Inquiry
BSFAB-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD7 saporin Inquiry
BSFAB-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD38 saporin Inquiry
BSFAB-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD37 saporin Inquiry
BSFAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 CD22 Inquiry
BSFAB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 CD22 Inquiry
BSFV-130 Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD7 saporin Inquiry
BSFV-120 Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD38 saporin Inquiry
BSFV-118 Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD37 saporin Inquiry
BSFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 CD22 Inquiry
BSFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 CD22 Inquiry

Background

CD22 (Cluster of differentiation 22), also referred to SIGLEC2 or B-cell receptor CD22, is a 135-140 kDa transmembrane glycoprotein and a member of the SIGLEC family of lectins. The protein encoded by this gene is localized at the chromosome 19q13.12 and codes for alternative spliced forms including CD22, CD22α, and CD22β. of which the latter is the predominant species expressed by B cells. The expression of CD22 is restricted to the cytoplasm of pre-B cells and progenitor in the early B-cell development. CD22 serves as a cell adhesion receptor for sialic acid-bearing ligands which is expressed on erythrocytes and all leukocytes. Additionally, CD22-mediated signal transduction can activate B cells and modulate antigen receptor signaling in vitro. Saporin, also referred as saporin-S6, is a type I RIP isolated from the seeds of Saponaria officinalis. The mature form of saporin is composed of 253 amino acids19. Due to the lack of receptor binding domain, saporin by itself enters cells at low efficiency. However, when conjugated to cell surface targeting molecules, saporin actively enters the cells through endocytosis, cleaves 28S rRNA, inhibits protein synthesis, induces apoptosis, and causes cell death.
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