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CD28 & CD3 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H228 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD28 Human CD3 Human Inquiry
T-BSDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD28 Mouse CD3 Mouse Inquiry
SCIGG-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scIgG) Human Single chain IgGs CD28 Human CD3 Human Inquiry
FABVC-366 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-sdAb-Fc) Human Fab-scFv/sdAb-Fc CD28 Mouse CD3 llama Inquiry
BSSG-366 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (sdAb-IgG) Human sdAb-IgG CD28 Mouse CD3 llama Inquiry
HCAB-011 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (sdAb-Fc-sdAb) Human sdAb-Fc-sdAb CD28 llama CD3 llama Inquiry
BIBD-366 Recombinant Anti-CD28 x Anti-CD3 VHH BispecificAntibody (Bibody) Human Bibody CD28 Mouse CD3 llama Inquiry
IGVHH-011 Recombinant Anti-CD28 x Anti-CD3 sdAb Bispecific Antibody (IgG-sdAb) Human IgG-sdAb CD28 Mouse CD3 llama Inquiry
BIVHH-011 Recombinant Anti-CD28 sdAb x Anti-CD3 sdAb Bispecific Antibody (Bi-sdAb) Human Bi-sdAb CD28 llama CD3 llama Inquiry
SCIGG-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scIgG) Human Single chain IgGs CD28 Mouse CD3 Mouse Inquiry
FVTIG-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD28 Human CD3 Human Inquiry
FVTIG-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD28 Mouse CD3 Mouse Inquiry
BSSG-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD28 Human CD3 Human Inquiry
BSSG-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD28 Mouse CD3 Mouse Inquiry
IGLFV-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD28 Human CD3 Human Inquiry
IGLFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD28 Mouse CD3 Mouse Inquiry
BSGV-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD28 Mouse CD3 Mouse Inquiry
BSGV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD28 Mouse CD3 Mouse Inquiry
BSDG-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD28 Human CD3 Human Inquiry
BSDG-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD28 Mouse CD3 Mouse Inquiry
BABFV-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD28 Human CD3 Human Inquiry
BABFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD28 Mouse CD3 Mouse Inquiry
FABVC-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD28 Human CD3 Human Inquiry
FABVC-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD28 Mouse CD3 Mouse Inquiry
SCDBC-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD28 Human CD3 Human Inquiry
SCDBC-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD28 Mouse CD3 Mouse Inquiry
BSDBC-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD28 Human CD3 Human Inquiry
BSDBC-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD28 Mouse CD3 Mouse Inquiry
SCDBF-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD28 Human CD3 Human Inquiry
SCDBF-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD28 Mouse CD3 Mouse Inquiry
BSFVF-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD28 Human CD3 Human Inquiry
BSFVF-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD28 Mouse CD3 Mouse Inquiry
BSDBF-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD28 Human CD3 Human Inquiry
BSDBF-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD28 Mouse CD3 Mouse Inquiry
BSTF-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD28 Mouse CD3 Mouse Inquiry
BSTF-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD28 Mouse CD3 Mouse Inquiry
BSCFV-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD28 Mouse CD3 Mouse Inquiry
BSCFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD28 Mouse CD3 Mouse Inquiry
MNAB-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Miniantibody) Human Miniantibody CD28 Mouse CD3 Mouse Inquiry
MNAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Miniantibody) Human Miniantibody CD28 Mouse CD3 Mouse Inquiry
BSFC-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD28 Mouse CD3 Mouse Inquiry
BSFC-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD28 Mouse CD3 Mouse Inquiry
BSCC-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD28 Mouse CD3 Mouse Inquiry
BSCC-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD28 Mouse CD3 Mouse Inquiry
BIBD-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Bibody) Human Bibody CD28 Mouse CD3 Mouse Inquiry
BIBD-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Bibody) Human Bibody CD28 Mouse CD3 Mouse Inquiry
FABFV-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Human CD3 Human Inquiry
FABFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CD3 Mouse Inquiry
MiniB-H230 Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Minibody) Human Minibody CD28 Human CD3 Human Inquiry
MiniB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Minibody) Human Minibody CD28 Mouse CD3 Mouse Inquiry
SCDB-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 Human CD3 Human Inquiry
FABIG-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 Human CD3 Human Inquiry
TRIB-H230 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Human CD3 Human Inquiry
BSIG-H228 Human Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Human CD3 Human Inquiry
CROSSAB-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD28 Human CD3 Human Inquiry
IGFV-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Human CD3 Human Inquiry
BSDB-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD28 Human CD3 Human Inquiry
BSFAB-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Human CD3 Human Inquiry
BSFV-H228 Recombinant Human Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Human CD3 Human Inquiry
SCDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 Mouse CD3 Mouse Inquiry
FABIG-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 Mouse CD3 Mouse Inquiry
TRIB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse CD3 Mouse Inquiry
BSIG-054 Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD3 Mouse Inquiry
CROSSAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD3 Mouse Inquiry
IGFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD3 Mouse Inquiry
BSDB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD3 Mouse Inquiry
BSFAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD3 Mouse Inquiry
BSFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD3 Mouse Inquiry
BSFAB-072 Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CEA Mouse Inquiry
BSFAB-071 Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD8 Mouse Inquiry
BSFAB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD79B Mouse Inquiry
BSFAB-069 Recombinant Anti-CD3 x Anti-CD74 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD74 Mouse Inquiry
BSFAB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD44 Mouse Inquiry
BSFAB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD4 Mouse Inquiry
BSFAB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD33 Mouse Inquiry
BSFAB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD30 Mouse Inquiry
BSFAB-064 Recombinant Anti-CD3 x Anti-B7H3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse B7H3 Mouse Inquiry
BSFAB-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CSPG4 Mouse Inquiry
BSFAB-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse MUC1 Mouse Inquiry
BSFAB-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse HN Mouse Inquiry
BSFAB-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse FOLR1 Mouse Inquiry
BSFAB-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EPCAM Mouse Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EGFR Mouse Inquiry
BSFAB-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD44 Mouse Inquiry
BSFAB-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD40 Mouse Inquiry
BSFAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD30 Mouse Inquiry
BSFAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD3 Mouse Inquiry
BSFAB-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD28 Mouse Inquiry
BSFAB-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD3 Mouse Inquiry
BSFAB-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD28 Mouse Inquiry
BSFAB-030 Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD123 Mouse CD3 Mouse Inquiry
BSFAB-029 Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CCR5 Mouse CD3 Mouse Inquiry
BSFAB-027 Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CA72-4 Mouse CD3 Mouse Inquiry
BSFAB-026 Recombinant Anti-CA19-9 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CA19-9 Mouse CD3 Mouse Inquiry
BSFAB-020 Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab BCMA Mouse CD3 Mouse Inquiry
BSFAB-017 Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab B7H6 Mouse CD3 Mouse Inquiry
BSFAB-016 Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma BCL1 Idiotype Rat CD3 Mouse Inquiry
BSFAB-015 Recombinant Anti-B Cell Lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma A20-HL Idiotype Rat CD3 Mouse Inquiry
BSFV-144 Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv Csl Mouse CD3 Mouse Inquiry
BSFV-109 Recombinant Anti-CD3 x Anti-VEGFR2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse VEGFR2 Mouse Inquiry
BSFV-108 Recombinant Anti-CD3 x Anti-VEGFR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse VEGFR1 Mouse Inquiry
BSFV-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TROP2 Mouse Inquiry
BSFV-106 Recombinant Anti-CD3 x Anti-TPBG Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TPBG Mouse Inquiry
BSFV-105 Recombinant Anti-CD3 x Anti-THY1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse THY1 Mouse Inquiry
BSFV-104 Recombinant Anti-CD3 x Anti-TFRC Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TFRC Mouse Inquiry
BSFV-103 Recombinant Anti-CD3 x Anti-SCLC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse SCLC1 Mouse Inquiry
BSFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSMA Mouse Inquiry
BSFV-101 Recombinant Anti-CD3 x Anti-PSCA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSCA Mouse Inquiry
BSFV-100 Recombinant Anti-CD3 x Anti-PSA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSA Mouse Inquiry
BSFV-099 Recombinant Anti-CD3 x Anti-PLAP Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PLAP Mouse Inquiry
BSFV-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PD1 Mouse Inquiry
BSFV-097 Recombinant Anti-CD3 x Anti-p97 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse p97 Mouse Inquiry
BSFV-096 Recombinant Anti-CD3 x Anti-P cadherin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse P-Cadherin Mouse Inquiry
BSFV-095 Recombinant Anti-CD3 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse MUC1 Mouse Inquiry
BSFV-094 Recombinant Anti-CD3 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CSPG4 Mouse Inquiry
BSFV-093 Recombinant Anti-CD3 x Anti-IL2R Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse IL2R Mouse Inquiry
BSFV-092 Recombinant Anti-CD3 x Anti-IGF1R Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse IGF1R Mouse Inquiry
BSFV-091 Recombinant Anti-CD3 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HN Mouse Inquiry
BSFV-090 Recombinant Anti-CD3 x Anti-HER2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HER2 Mouse Inquiry
BSFV-089 Recombinant Anti-CD3 x Anti-HBVgp3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HBVgp3 Mouse Inquiry
BSFV-088 Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GPNMB Mouse Inquiry
BSFV-087 Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GPC3 Mouse Inquiry
BSFV-086 Recombinant Anti-CD3 x Anti-gpA33 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse gpA33 Mouse Inquiry
BSFV-085 Recombinant Anti-CD3 x Anti-HIV-1 gp41 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HIV-1 gp41 Mouse Inquiry
BSFV-084 Recombinant Anti-CD3 x Anti-HIV-1 gp120 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HIV-1 gp120 Mouse Inquiry
BSFV-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GD2 Mouse Inquiry
BSFV-082 Recombinant Anti-CD3 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse FOLR1 Mouse Inquiry
BSFV-081 Recombinant Anti-CD3 x Anti-FcRH5 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse FcRH5 Mouse Inquiry
BSFV-080 Recombinant Anti-CD3 x Anti-FAP Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse FAP Mouse Inquiry
BSFV-079 Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EPCAM Mouse Inquiry
BSFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD248 Mouse Inquiry
BSFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EGFR Mouse Inquiry
BSFV-076 Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse DLL3 Mouse Inquiry
BSFV-075 Recombinant Anti-CD3 x Anti-CXCR5 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CXCR5 Mouse Inquiry
BSFV-074 Recombinant Anti-CD3 x Anti-MET Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse MET Mouse Inquiry
BSFV-073 Recombinant Anti-CD3 x Anti-CLEC12A Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CLEC12A Mouse Inquiry
BSFV-072 Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CEA Mouse Inquiry
BSFV-071 Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD8 Mouse Inquiry
BSFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD79B Mouse Inquiry
BSFV-069 Recombinant Anti-CD3 x Anti-CD74 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD74 Mouse Inquiry
BSFV-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD44 Mouse Inquiry
BSFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD4 Mouse Inquiry
BSFV-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD33 Mouse Inquiry
BSFV-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD30 Mouse Inquiry
BSFV-064 Recombinant Anti-CD3 x Anti-B7H3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse B7H3 Mouse Inquiry
BSFV-063 Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CSPG4 Mouse Inquiry
BSFV-062 Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse MUC1 Mouse Inquiry
BSFV-061 Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse HN Mouse Inquiry
BSFV-060 Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse FOLR1 Mouse Inquiry
BSFV-059 Recombinant Anti-CD28 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EPCAM Mouse Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EGFR Mouse Inquiry
BSFV-057 Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD44 Mouse Inquiry
BSFV-056 Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD40 Mouse Inquiry
BSFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD30 Mouse Inquiry
BSFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD3 Mouse Inquiry
BSFV-050 Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD28 Mouse Inquiry
BSFV-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD3 Mouse Inquiry
BSFV-040 Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD28 Mouse Inquiry
BSFV-030 Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD123 Mouse CD3 Mouse Inquiry
BSFV-029 Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CCR5 Mouse CD3 Mouse Inquiry
BSFV-027 Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CA72-4 Mouse CD3 Mouse Inquiry
BSFV-026 Recombinant Anti-CA19-9 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CA19-9 Mouse CD3 Mouse Inquiry
BSFV-020 Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv BCMA Mouse CD3 Mouse Inquiry
BSFV-017 Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv B7H6 Mouse CD3 Mouse Inquiry
BSFV-016 Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma BCL1 Idiotype Rat CD3 Mouse Inquiry
BSFV-015 Recombinant Anti-B Cell Lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma A20-HL Idiotype Rat CD3 Mouse Inquiry

Background

CD28 and CD3 are proteins found on the surface of T cells. CD28 is a co-stimulatory molecule that activates T cells upon binding with B7 on antigen-presenting cells (APCs), while CD3 is essential for T cell receptor signaling. The anti-CD28×anti-CD3 bispecific antibody (BsAb) is designed to bind simultaneously to CD28 and CD3, bridging the interaction between T cells and APCs. This results in the activation and potentiation of T cells, leading to their enhanced cytotoxic activity against cancer cells or infected cells. The BsAb has shown promising results in studies on a variety of cancers, including hematological malignancies and solid tumors. It offers a targeted approach with minimal off-target effects, making it a potential breakthrough in cancer immunotherapy.

Fig.1 Optimizing CODV bispecific Fab α-CD3/α-CD28 combinations. (Wu, et al., 2020) Fig.1 The evaluation of CODV bispecific Fab α-CD3/α-CD28 optimal configurations.1

Reference

  1. Wu, Lan, et al. "Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation." Nature Cancer 1.1 (2020): 86-98.
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