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CD3 & EGFR Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H251 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD3 Human EGFR Human Inquiry
T-BSDB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD3 Mouse EGFR Mouse Inquiry
KN-0422-LN4 Recombinant Anti-CD3 (O-OKT3) x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EGFR Human Inquiry
KN-0422-LN3 Recombinant Anti-CD3 (R-OKT3) x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EGFR Mouse Inquiry
SCIGG-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scIgG) Human Single chain IgGs CD3 Human EGFR Human Inquiry
FABVC-375 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-sdAb-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse EGFR llama Inquiry
BSSG-375 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (sdAb-IgG) Human sdAb-IgG CD3 Mouse EGFR llama Inquiry
HCAB-020 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (sdAb-Fc-sdAb) Human sdAb-Fc-sdAb CD3 llama EGFR llama Inquiry
BIBD-375 Recombinant Anti-CD3 x Anti-EGFR VHH BispecificAntibody (Bibody) Human Bibody CD3 Mouse EGFR llama Inquiry
IGVHH-020 Recombinant Anti-CD3 x Anti-EGFR sdAb Bispecific Antibody (IgG-sdAb) Human IgG-sdAb CD3 Mouse EGFR llama Inquiry
BIVHH-020 Recombinant Anti-CD3 sdAb x Anti-EGFR sdAb Bispecific Antibody (Bi-sdAb) Human Bi-sdAb CD3 llama EGFR llama Inquiry
SCIGG-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scIgG) Human Single chain IgGs CD3 Mouse EGFR Mouse Inquiry
FVTIG-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Human EGFR Human Inquiry
FVTIG-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Mouse EGFR Mouse Inquiry
BSSG-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Human EGFR Human Inquiry
BSSG-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Mouse EGFR Mouse Inquiry
IGLFV-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Human EGFR Human Inquiry
IGLFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Mouse EGFR Mouse Inquiry
BSGV-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse EGFR Mouse Inquiry
BSGV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse EGFR Mouse Inquiry
BSDG-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Human EGFR Human Inquiry
BSDG-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Mouse EGFR Mouse Inquiry
BABFV-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Human EGFR Human Inquiry
BABFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Mouse EGFR Mouse Inquiry
FABVC-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Human EGFR Human Inquiry
FABVC-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse EGFR Mouse Inquiry
SCDBC-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Human EGFR Human Inquiry
SCDBC-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Mouse EGFR Mouse Inquiry
BSDBC-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Human EGFR Human Inquiry
BSDBC-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Mouse EGFR Mouse Inquiry
SCDBF-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Human EGFR Human Inquiry
SCDBF-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Mouse EGFR Mouse Inquiry
BSFVF-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Human EGFR Human Inquiry
BSFVF-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Mouse EGFR Mouse Inquiry
BSDBF-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Human EGFR Human Inquiry
BSDBF-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Mouse EGFR Mouse Inquiry
BSTF-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse EGFR Mouse Inquiry
BSTF-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse EGFR Mouse Inquiry
BSCFV-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse EGFR Mouse Inquiry
BSCFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse EGFR Mouse Inquiry
MNAB-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse EGFR Mouse Inquiry
MNAB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse EGFR Mouse Inquiry
BSFC-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse EGFR Mouse Inquiry
BSFC-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse EGFR Mouse Inquiry
BSCC-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse EGFR Mouse Inquiry
BSCC-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse EGFR Mouse Inquiry
BIBD-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Bibody) Human Bibody CD3 Mouse EGFR Mouse Inquiry
BIBD-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Bibody) Human Bibody CD3 Mouse EGFR Mouse Inquiry
FABFV-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human EGFR Human Inquiry
FABFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse EGFR Mouse Inquiry
MiniB-H253 Recombinant Human Anti-CD3 x Human Anti-EGFR Bispecific Antibody (Minibody) Human Minibody CD3 Human EGFR Human Inquiry
MiniB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Minibody) Human Minibody CD3 Mouse EGFR Mouse Inquiry
SCTB-H148 Recombinant Human Anti-EGFR x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human EGFR Human Inquiry
SCDB-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human EGFR Human Inquiry
FABIG-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human EGFR Human Inquiry
TRIB-H253 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human EGFR Human Inquiry
BSIG-H251 Human Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human EGFR Human Inquiry
CROSSAB-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD3 Human EGFR Human Inquiry
IGFV-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human EGFR Human Inquiry
BSDB-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD3 Human EGFR Human Inquiry
BSFAB-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human EGFR Human Inquiry
BSFV-H251 Recombinant Human Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human EGFR Human Inquiry
SCTB-050 Recombinant Anti-EGFR x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse EGFR Mouse Inquiry
SCDB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse EGFR Mouse Inquiry
FABIG-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse EGFR Mouse Inquiry
TRIB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse EGFR Mouse Inquiry
BSIG-077 Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse EGFR Mouse Inquiry
CROSSAB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse EGFR Mouse Inquiry
IGFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse EGFR Mouse Inquiry
BSDB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD3 Mouse EGFR Mouse Inquiry
BSFAB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse EGFR Mouse Inquiry
BSFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EGFR Mouse Inquiry
BSFAB-079 Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse EPCAM Mouse Inquiry
BSFAB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD248 Mouse Inquiry
BSFAB-076 Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse DLL3 Mouse Inquiry
BSFAB-075 Recombinant Anti-CD3 x Anti-CXCR5 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CXCR5 Mouse Inquiry
BSFAB-074 Recombinant Anti-CD3 x Anti-MET Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse MET Mouse Inquiry
BSFAB-073 Recombinant Anti-CD3 x Anti-CLEC12A Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CLEC12A Mouse Inquiry
BSFAB-072 Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CEA Mouse Inquiry
BSFAB-071 Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD8 Mouse Inquiry
BSFAB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD79B Mouse Inquiry
BSFAB-069 Recombinant Anti-CD3 x Anti-CD74 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD74 Mouse Inquiry
BSFAB-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD44 Mouse Inquiry
BSFAB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD4 Mouse Inquiry
BSFAB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD33 Mouse Inquiry
BSFAB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD30 Mouse Inquiry
BSFAB-064 Recombinant Anti-CD3 x Anti-B7H3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse B7H3 Mouse Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EGFR Mouse Inquiry
BSFAB-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD3 Mouse Inquiry
BSFAB-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD3 Mouse Inquiry
BSFAB-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD2 Mouse EGFR Mouse Inquiry
BSFAB-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD3 Mouse Inquiry
BSFAB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 Mouse EGFR Mouse Inquiry
BSFAB-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD133 Mouse EGFR Mouse Inquiry
BSFAB-030 Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD123 Mouse CD3 Mouse Inquiry
BSFAB-029 Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CCR5 Mouse CD3 Mouse Inquiry
BSFAB-027 Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CA72-4 Mouse CD3 Mouse Inquiry
BSFAB-026 Recombinant Anti-CA19-9 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CA19-9 Mouse CD3 Mouse Inquiry
BSFAB-020 Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab BCMA Mouse CD3 Mouse Inquiry
BSFAB-017 Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem Fab) Human Tandem Fab B7H6 Mouse CD3 Mouse Inquiry
BSFAB-016 Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma BCL1 Idiotype Rat CD3 Mouse Inquiry
BSFAB-015 Recombinant Anti-B Cell Lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma A20-HL Idiotype Rat CD3 Mouse Inquiry
BSFV-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse ZnO Mouse Inquiry
BSFV-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse IGF1R Mouse Inquiry
BSFV-156 Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse HER3 Mouse Inquiry
BSFV-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse HER2 Mouse Inquiry
BSFV-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse MET Mouse Inquiry
BSFV-144 Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv Csl Mouse CD3 Mouse Inquiry
BSFV-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD89 Mouse EGFR Mouse Inquiry
BSFV-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD64 Mouse EGFR Mouse Inquiry
BSFV-109 Recombinant Anti-CD3 x Anti-VEGFR2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse VEGFR2 Mouse Inquiry
BSFV-108 Recombinant Anti-CD3 x Anti-VEGFR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse VEGFR1 Mouse Inquiry
BSFV-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TROP2 Mouse Inquiry
BSFV-106 Recombinant Anti-CD3 x Anti-TPBG Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TPBG Mouse Inquiry
BSFV-105 Recombinant Anti-CD3 x Anti-THY1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse THY1 Mouse Inquiry
BSFV-104 Recombinant Anti-CD3 x Anti-TFRC Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TFRC Mouse Inquiry
BSFV-103 Recombinant Anti-CD3 x Anti-SCLC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse SCLC1 Mouse Inquiry
BSFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSMA Mouse Inquiry
BSFV-101 Recombinant Anti-CD3 x Anti-PSCA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSCA Mouse Inquiry
BSFV-100 Recombinant Anti-CD3 x Anti-PSA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSA Mouse Inquiry
BSFV-099 Recombinant Anti-CD3 x Anti-PLAP Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PLAP Mouse Inquiry
BSFV-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PD1 Mouse Inquiry
BSFV-097 Recombinant Anti-CD3 x Anti-p97 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse p97 Mouse Inquiry
BSFV-096 Recombinant Anti-CD3 x Anti-P cadherin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse P-Cadherin Mouse Inquiry
BSFV-095 Recombinant Anti-CD3 x Anti-MUC1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse MUC1 Mouse Inquiry
BSFV-094 Recombinant Anti-CD3 x Anti-CSPG4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CSPG4 Mouse Inquiry
BSFV-093 Recombinant Anti-CD3 x Anti-IL2R Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse IL2R Mouse Inquiry
BSFV-092 Recombinant Anti-CD3 x Anti-IGF1R Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse IGF1R Mouse Inquiry
BSFV-091 Recombinant Anti-CD3 x Anti-HN Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HN Mouse Inquiry
BSFV-090 Recombinant Anti-CD3 x Anti-HER2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HER2 Mouse Inquiry
BSFV-089 Recombinant Anti-CD3 x Anti-HBVgp3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HBVgp3 Mouse Inquiry
BSFV-088 Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GPNMB Mouse Inquiry
BSFV-087 Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GPC3 Mouse Inquiry
BSFV-086 Recombinant Anti-CD3 x Anti-gpA33 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse gpA33 Mouse Inquiry
BSFV-085 Recombinant Anti-CD3 x Anti-HIV-1 gp41 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HIV-1 gp41 Mouse Inquiry
BSFV-084 Recombinant Anti-CD3 x Anti-HIV-1 gp120 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse HIV-1 gp120 Mouse Inquiry
BSFV-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GD2 Mouse Inquiry
BSFV-082 Recombinant Anti-CD3 x Anti-FOLR1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse FOLR1 Mouse Inquiry
BSFV-081 Recombinant Anti-CD3 x Anti-FcRH5 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse FcRH5 Mouse Inquiry
BSFV-080 Recombinant Anti-CD3 x Anti-FAP Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse FAP Mouse Inquiry
BSFV-079 Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EPCAM Mouse Inquiry
BSFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD248 Mouse Inquiry
BSFV-076 Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse DLL3 Mouse Inquiry
BSFV-075 Recombinant Anti-CD3 x Anti-CXCR5 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CXCR5 Mouse Inquiry
BSFV-074 Recombinant Anti-CD3 x Anti-MET Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse MET Mouse Inquiry
BSFV-073 Recombinant Anti-CD3 x Anti-CLEC12A Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CLEC12A Mouse Inquiry
BSFV-072 Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CEA Mouse Inquiry
BSFV-071 Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD8 Mouse Inquiry
BSFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD79B Mouse Inquiry
BSFV-069 Recombinant Anti-CD3 x Anti-CD74 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD74 Mouse Inquiry
BSFV-068 Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD44 Mouse Inquiry
BSFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD4 Mouse Inquiry
BSFV-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD33 Mouse Inquiry
BSFV-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD30 Mouse Inquiry
BSFV-064 Recombinant Anti-CD3 x Anti-B7H3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse B7H3 Mouse Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EGFR Mouse Inquiry
BSFV-054 Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD3 Mouse Inquiry
BSFV-051 Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD3 Mouse Inquiry
BSFV-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD2 Mouse EGFR Mouse Inquiry
BSFV-041 Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD3 Mouse Inquiry
BSFV-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 Mouse EGFR Mouse Inquiry
BSFV-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD133 Mouse EGFR Mouse Inquiry
BSFV-030 Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD123 Mouse CD3 Mouse Inquiry
BSFV-029 Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CCR5 Mouse CD3 Mouse Inquiry
BSFV-027 Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CA72-4 Mouse CD3 Mouse Inquiry
BSFV-026 Recombinant Anti-CA19-9 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CA19-9 Mouse CD3 Mouse Inquiry
BSFV-020 Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv BCMA Mouse CD3 Mouse Inquiry
BSFV-017 Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem scFv) Human Tandem scFv B7H6 Mouse CD3 Mouse Inquiry
BSFV-016 Recombinant Anti-B Cell Lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma BCL1 Idiotype Rat CD3 Mouse Inquiry
BSFV-015 Recombinant Anti-B Cell Lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma A20-HL Idiotype Rat CD3 Mouse Inquiry

Background

CD3 is an immunoglobulin superfamily member that functions as a signal transduction mediator. It is a multimeric protein made up of four different polypeptide chains (ε, γ, δ, ζ), and CD3 is required for T cell activation and development. Epidermal growth factor receptor (EGFR) is a member of the erbB receptor tyrosine kinase family, which includes four related transmembrane glycoprotein membrane receptors: erbB1 (EGFR), erbB2 (HER2/neu), erbB3 (HER3), and erbB4 (HER4). Overexpression of EGFR in various cancers makes it an important target for cancer immunotherapy. When anti-CD3 activated T cells are treated with an anti-CD3×anti-EGFR bispecific antibody, each activated T cell becomes a specific cytotoxic T lymphocyte. Figure 1 shows an IgG-like bispecific antibody binding a tumor-associated antigen EGFR on a cancer cell and CD3 on a T cell to steer T cell cytotoxicity to tumor cells. This bispecific antibody can not only stimulate T cells, but can also be dosage controlled to prevent toxicity.

Fig.1 The CD3+×EGFR+ bispecific T-cell redirection strategy harnesses the body's immune system to specifically target and eliminate cancer cells expressing EGFR. (Singh, et al , 2021) Fig.1 Mechanism of action of CD3+×EGFR+ bispecific T-cell redirection in cancer.1

Reference

  1. Singh, Ajit, Sundee Dees, and Iqbal S. Grewal. "Overcoming the challenges associated with CD3+ T-cell redirection in cancer." British journal of cancer 124.6 (2021): 1037-1048.
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