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CD317 & CD16 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem Diabody) Human CD317 CD16 Inquiry
T-BSDB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem Diabody) Human CD317 CD16 Inquiry
SCIGG-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scIgG) Human Single chain IgGs CD317 CD16 Inquiry
SCIGG-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scIgG) Human Single chain IgGs CD317 CD16 Inquiry
FVTIG-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD317 CD16 Inquiry
FVTIG-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scFv4-Ig) Human Appended IgGs CD317 CD16 Inquiry
BSSG-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD317 CD16 Inquiry
BSSG-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scFv-IgG) Human Appended IgGs CD317 CD16 Inquiry
IGLFV-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD317 CD16 Inquiry
IGLFV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs CD317 CD16 Inquiry
BSGV-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD317 CD16 Inquiry
BSGV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD317 CD16 Inquiry
BSDG-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD317 CD16 Inquiry
BSDG-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Fv-IgG) Human Appended IgGs CD317 CD16 Inquiry
BABFV-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD317 CD16 Inquiry
BABFV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins CD317 CD16 Inquiry
FABVC-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD317 CD16 Inquiry
FABVC-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins CD317 CD16 Inquiry
SCDBC-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
SCDBC-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSDBC-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSDBC-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
SCDBF-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
SCDBF-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSFVF-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSFVF-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSDBF-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSDBF-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments CD317 CD16 Inquiry
BSTF-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSTF-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSCFV-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSCFV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
MNAB-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
MNAB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSFC-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSFC-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSCC-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BSCC-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments CD317 CD16 Inquiry
BIBD-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Bibody) Human Bibody CD317 CD16 Inquiry
BIBD-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Bibody) Human Bibody CD317 CD16 Inquiry
FABFV-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD317 CD16 Inquiry
FABFV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD317 CD16 Inquiry
MiniB-H287 Recombinant Human Anti-CD317 x Human Anti-CD16 Bispecific Antibody (Minibody) Human Minibody CD317 CD16 Inquiry
MiniB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Minibody) Human Minibody CD317 CD16 Inquiry
SCTB-H180 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD317 CD16 Inquiry
SCDB-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD317 CD16 Inquiry
FABIG-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD317 CD16 Inquiry
TRIB-H287 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Triple Body) Human Triple Body CD317 CD16 Inquiry
BSIG-H285 Human Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD317 CD16 Inquiry
CROSSAB-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (CrossMab) Human CrossMab CD317 CD16 Inquiry
IGFV-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD317 CD16 Inquiry
BSDB-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Diabody) Human Diabody CD317 CD16 Inquiry
BSFAB-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD317 CD16 Inquiry
BSFV-H285 Recombinant Human Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD317 CD16 Inquiry
SCTB-084 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD317 CD16 Inquiry
SCDB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD317 CD16 Inquiry
FABIG-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD317 CD16 Inquiry
TRIB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Triple Body) Human Triple Body CD317 CD16 Inquiry
BSIG-111 Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD317 CD16 Inquiry
CROSSAB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (CrossMab) Human CrossMab CD317 CD16 Inquiry
IGFV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD317 CD16 Inquiry
BSDB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Diabody) Human Diabody CD317 CD16 Inquiry
BSFAB-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD317 CD16 Inquiry
BSFV-111 Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD317 CD16 Inquiry
IGFV-H213 Recombinant Human Anti-CD16 x Anti-HER2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 HER2 Inquiry
IGFV-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 GD2 Inquiry
IGFV-H211 Recombinant Human Anti-CD16 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 EGFR Inquiry
IGFV-H210 Recombinant Human Anti-CD16 x Anti-CD32B Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 CD32B Inquiry
IGFV-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 CD30 Inquiry
BSDB-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Diabody) Human Diabody CD33 CD16 Inquiry
BSDB-H213 Recombinant Human Anti-CD16 x Anti-HER2 Bispecific Antibody (Diabody) Human Diabody CD16 HER2 Inquiry
BSDB-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD16 GD2 Inquiry
BSDB-H211 Recombinant Human Anti-CD16 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD16 EGFR Inquiry
BSDB-H210 Recombinant Human Anti-CD16 x Anti-CD32B Bispecific Antibody (Diabody) Human Diabody CD16 CD32B Inquiry
BSDB-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD16 CD30 Inquiry
BSFAB-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 CD16 Inquiry
BSFAB-H213 Recombinant Human Anti-CD16 x Anti-HER2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 HER2 Inquiry
BSFAB-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 GD2 Inquiry
BSFAB-H211 Recombinant Human Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 EGFR Inquiry
BSFAB-H210 Recombinant Human Anti-CD16 x Anti-CD32B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 CD32B Inquiry
BSFAB-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 CD30 Inquiry
BSFV-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 CD16 Inquiry
BSFV-H213 Recombinant Human Anti-CD16 x Anti-HER2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 HER2 Inquiry
BSFV-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 GD2 Inquiry
BSFV-H211 Recombinant Human Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 EGFR Inquiry
BSFV-H210 Recombinant Human Anti-CD16 x Anti-CD32B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 CD32B Inquiry
BSFV-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 CD30 Inquiry
SCTB-105 Recombinant Anti-CD33 x Anti-CD16 x Anti-CD19 Trispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 CD16 Inquiry
SCTB-104 Recombinant Anti-CD33 x Anti-CD16 x CD123 Trispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 CD16 Inquiry
SCTB-086 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 CD16 Inquiry
SCTB-014 Recombinant Anti-HER2 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 HER2 Inquiry
SCTB-013 Recombinant Anti-GD2 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 GD2 Inquiry
SCTB-012 Recombinant Anti-EGFR x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 EGFR Inquiry
SCTB-011 Recombinant Anti-CD30 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 CD30 Inquiry
SCDB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 CD16 Inquiry
SCDB-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 HER2 Inquiry
SCDB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 GD2 Inquiry
SCDB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 EGFR Inquiry
SCDB-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 CD32B Inquiry
SCDB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 CD30 Inquiry
FABIG-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 CD16 Inquiry
FABIG-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 HER2 Inquiry
FABIG-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 GD2 Inquiry
FABIG-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 EGFR Inquiry
FABIG-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 CD32B Inquiry
FABIG-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 CD30 Inquiry
TRIB-193 Recombinant Anti-CD16 x Anti-CD33 x Anti-CD19 Trispecific Antibody (Triple Body) Human Triple Body CD16 CD33 Inquiry
TRIB-192 Recombinant Anti-CD16 x Anti-CD33 x Anti-CD123 Trispecific Antibody (Triple Body) Human Triple Body CD16 CD33 Inquiry
TRIB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Triple Body) Human Triple Body CD33 CD16 Inquiry
TRIB-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Triple Body) Human Triple Body CD16 HER2 Inquiry
TRIB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Triple Body) Human Triple Body CD16 GD2 Inquiry
TRIB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Triple Body) Human Triple Body CD16 EGFR Inquiry
TRIB-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Triple Body) Human Triple Body CD16 CD32B Inquiry
TRIB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Triple Body) Human Triple Body CD16 CD30 Inquiry
BSIG-114 Anti-CD33 x Anti-CD16 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 CD16 Inquiry
BSIG-038 Anti-CD16 x Anti-HER2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 HER2 Inquiry
BSIG-037 Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 GD2 Inquiry
BSIG-036 Anti-CD16 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 EGFR Inquiry
BSIG-035 Anti-CD16 x Anti-CD32B Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 CD32B Inquiry
BSIG-034 Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 CD30 Inquiry
CROSSAB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (CrossMab) Human CrossMab CD33 CD16 Inquiry
CROSSAB-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (CrossMab) Human CrossMab CD16 HER2 Inquiry
CROSSAB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD16 GD2 Inquiry
CROSSAB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD16 EGFR Inquiry
CROSSAB-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (CrossMab) Human CrossMab CD16 CD32B Inquiry
CROSSAB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD16 CD30 Inquiry
IGFV-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 CD16 Inquiry
IGFV-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 HER2 Inquiry
IGFV-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 GD2 Inquiry
IGFV-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 EGFR Inquiry
IGFV-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 CD32B Inquiry
IGFV-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 CD30 Inquiry
BSDB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Diabody) Human Diabody CD33 CD16 Inquiry
BSDB-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Diabody) Human Diabody CD16 HER2 Inquiry
BSDB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD16 GD2 Inquiry
BSDB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD16 EGFR Inquiry
BSDB-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Diabody) Human Diabody CD16 CD32B Inquiry
BSDB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD16 CD30 Inquiry
BSFAB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 CD16 Inquiry
BSFAB-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 HER2 Inquiry
BSFAB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 GD2 Inquiry
BSFAB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 EGFR Inquiry
BSFAB-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 CD32B Inquiry
BSFAB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 CD30 Inquiry
BSFV-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 CD16 Inquiry
BSFV-038 Recombinant Anti-CD16 x Anti-HER2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 HER2 Inquiry
BSFV-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 GD2 Inquiry
BSFV-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 EGFR Inquiry
BSFV-035 Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 CD32B Inquiry
BSFV-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 CD30 Inquiry

Background

CD317 is a lipid raft-associated intrinsic immunological factor that is located on the surface and intracellular membranes of numerous cell types, including T cells and plasma-like dendritic cells. This factor directly sequesters enveloped HIV-1 particles to the cell surface, thereby triggering host immune responses. In tumor research, screenings have affirmed the up-regulated expression of CD317 in multiple myeloma and have recognized it as a prospective selective target.

CD317 signaling and functions. (Zhao, et al., 2022) Fig.1 CD317(BST2) function.1

CD16 is expressed by NK cells, macrophages, and some circulating monocytes. This molecule plays a crucial role in regulating the survival and proliferation of NK cells. Serving as an activating receptor for NK cells, it can prompt cytotoxic activities and engender a plethora of pro-inflammatory cytokines. This process sets in motion NK immune functions and anti-tumor capabilities.

Bispecific antibodies created from parental antibodies against CD317 and CD16 have the potential to concurrently connect CD16+ NK cells and CD317+ tumor cells, thereby boosting the recruitment and activation of tumor-infiltrating immune cells. As such, they are viewed as promising interventions for targeted treatments of multiple myeloma.

Multiple functions of CD16. (Capuano, et al., 2021) Fig.2 CD16 function.2

References

  1. Zhao, Zhao, et al. " Multi-functional BST2/tetherin against HIV-1, other viruses and LINE-1." Frontiers in Cellular and Infection Microbiology. 12 (2022): 979091.
  2. Capuano, Pighi, et al. " Harnessing CD16-mediated NK Cell functions to enhance therapeutic efficacy of tumor-targeting mAbs." Cancer. 13 (2021): 2500.
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