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CD45 & Myosin Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H294 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD45 Human Myosin Human Inquiry
T-BSDB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD45 Mouse Myosin Mouse Inquiry
SCIGG-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scIgG) Human Single chain IgGs CD45 Human Myosin Human Inquiry
SCIGG-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scIgG) Human Single chain IgGs CD45 Mouse Myosin Mouse Inquiry
FVTIG-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD45 Human Myosin Human Inquiry
FVTIG-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD45 Mouse Myosin Mouse Inquiry
BSSG-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scFv-IgG) Human scFv-IgG CD45 Human Myosin Human Inquiry
BSSG-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-IgG) Human scFv-IgG CD45 Mouse Myosin Mouse Inquiry
IGLFV-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD45 Human Myosin Human Inquiry
IGLFV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD45 Mouse Myosin Mouse Inquiry
BSGV-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (IgG-Fv) Human IgG-Fv CD45 Mouse Myosin Mouse Inquiry
BSGV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (IgG-Fv) Human IgG-Fv CD45 Mouse Myosin Mouse Inquiry
BSDG-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Fv-IgG) Human Fv-IgG CD45 Human Myosin Human Inquiry
BSDG-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Fv-IgG) Human Fv-IgG CD45 Mouse Myosin Mouse Inquiry
BABFV-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD45 Human Myosin Human Inquiry
BABFV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD45 Mouse Myosin Mouse Inquiry
FABVC-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD45 Human Myosin Human Inquiry
FABVC-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD45 Mouse Myosin Mouse Inquiry
SCDBC-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD45 Human Myosin Human Inquiry
SCDBC-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD45 Mouse Myosin Mouse Inquiry
BSDBC-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD45 Human Myosin Human Inquiry
BSDBC-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD45 Mouse Myosin Mouse Inquiry
SCDBF-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD45 Human Myosin Human Inquiry
SCDBF-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD45 Mouse Myosin Mouse Inquiry
BSFVF-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD45 Human Myosin Human Inquiry
BSFVF-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD45 Mouse Myosin Mouse Inquiry
BSDBF-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD45 Human Myosin Human Inquiry
BSDBF-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD45 Mouse Myosin Mouse Inquiry
BSTF-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD45 Mouse Myosin Mouse Inquiry
BSTF-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD45 Mouse Myosin Mouse Inquiry
BSCFV-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scFv-Fc) Human scFv-Fc CD45 Mouse Myosin Mouse Inquiry
BSCFV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-Fc) Human scFv-Fc CD45 Mouse Myosin Mouse Inquiry
MNAB-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Miniantibody) Human Miniantibody CD45 Mouse Myosin Mouse Inquiry
MNAB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Miniantibody) Human Miniantibody CD45 Mouse Myosin Mouse Inquiry
BSFC-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD45 Mouse Myosin Mouse Inquiry
BSFC-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD45 Mouse Myosin Mouse Inquiry
BSCC-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD45 Mouse Myosin Mouse Inquiry
BSCC-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD45 Mouse Myosin Mouse Inquiry
BIBD-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Bibody) Human Bibody CD45 Mouse Myosin Mouse Inquiry
BIBD-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Bibody) Human Bibody CD45 Mouse Myosin Mouse Inquiry
FABFV-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Fab-Fv) Human Fab-Fv CD45 Human Myosin Human Inquiry
FABFV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Fab-Fv) Human Fab-Fv CD45 Mouse Myosin Mouse Inquiry
MiniB-H296 Recombinant Human Anti-CD45 x Human Anti-Myosin Bispecific Antibody (Minibody) Human Minibody CD45 Human Myosin Human Inquiry
MiniB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Minibody) Human Minibody CD45 Mouse Myosin Mouse Inquiry
SCDB-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD45 Human Myosin Human Inquiry
FABIG-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD45 Human Myosin Human Inquiry
TRIB-H296 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD45 Human Myosin Human Inquiry
BSIG-H294 Human Anti-CD45 x Anti-Myosin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD45 Human Myosin Human Inquiry
CROSSAB-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (CrossMab) Human CrossMab CD45 Human Myosin Human Inquiry
IGFV-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD45 Human Myosin Human Inquiry
BSDB-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (Diabody) Human Diabody CD45 Human Myosin Human Inquiry
BSFAB-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD45 Human Myosin Human Inquiry
BSFV-H294 Recombinant Human Anti-CD45 x Anti-Myosin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD45 Human Myosin Human Inquiry
SCDB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD45 Mouse Myosin Mouse Inquiry
FABIG-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD45 Mouse Myosin Mouse Inquiry
TRIB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD45 Mouse Myosin Mouse Inquiry
BSIG-122 Anti-CD45 x Anti-Myosin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD45 Mouse Myosin Mouse Inquiry
CROSSAB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (CrossMab) Human CrossMab CD45 Mouse Myosin Mouse Inquiry
IGFV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD45 Mouse Myosin Mouse Inquiry
BSDB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Diabody) Human Diabody CD45 Mouse Myosin Mouse Inquiry
BSFAB-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD45 Mouse Myosin Mouse Inquiry
BSFV-122 Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD45 Mouse Myosin Mouse Inquiry

Background

CD45, a transmembrane protein tyrosine phosphatase found on the surface of all nucleated hematopoietic cells, plays a crucial role in regulating signaling processes during immune cell development, activation, and response. CD45 is a key regulator of lymphocyte signaling and is involved in the modulation of antigen receptor signaling thresholds. Myosin, a superfamily of motor proteins, is usually in association with actin filaments to produce force and movement within cells. In the context of muscle tissue, myosin participates in muscle contraction and movement. The anti-CD45×anti-myosin bispecific antibody can be constructed to simultaneously bind to CD45-expressing immune cells and myosin in muscle tissue, potentially modulating immune responses and affecting muscle function.

Fig.1 Functional mechanisms of CD45 and myosin. (Penninger, et al., 2001; Brito and Sandra, 2020) Fig.1 Functions of CD45 and myosin.1,2

References

  1. Penninger, Josef M., et al. "CD45: new jobs for an old acquaintance." Nature Immunology 2.5 (2001): 389-396.
  2. Brito, Cláudia, and Sandra Sousa. "Non-muscle myosin 2A (NM2A): structure, regulation and function." Cells 9.7 (2020): 1590.
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