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CR3 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H293 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD44 Human CR3 Human Inquiry
T-BSDB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD44 Mouse CR3 Mouse Inquiry
SCIGG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scIgG) Human Single chain IgGs CD44 Human CR3 Human Inquiry
SCIGG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scIgG) Human Single chain IgGs CD44 Mouse CR3 Mouse Inquiry
FVTIG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD44 Human CR3 Human Inquiry
FVTIG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD44 Mouse CR3 Mouse Inquiry
BSSG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD44 Human CR3 Human Inquiry
BSSG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD44 Mouse CR3 Mouse Inquiry
IGLFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD44 Human CR3 Human Inquiry
IGLFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD44 Mouse CR3 Mouse Inquiry
BSGV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD44 Mouse CR3 Mouse Inquiry
BSGV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD44 Mouse CR3 Mouse Inquiry
BSDG-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD44 Human CR3 Human Inquiry
BSDG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD44 Mouse CR3 Mouse Inquiry
BABFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD44 Human CR3 Human Inquiry
BABFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD44 Mouse CR3 Mouse Inquiry
FABVC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD44 Human CR3 Human Inquiry
FABVC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD44 Mouse CR3 Mouse Inquiry
SCDBC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD44 Human CR3 Human Inquiry
SCDBC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD44 Mouse CR3 Mouse Inquiry
BSDBC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD44 Human CR3 Human Inquiry
BSDBC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD44 Mouse CR3 Mouse Inquiry
SCDBF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD44 Human CR3 Human Inquiry
SCDBF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD44 Mouse CR3 Mouse Inquiry
BSFVF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD44 Human CR3 Human Inquiry
BSFVF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD44 Mouse CR3 Mouse Inquiry
BSDBF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD44 Human CR3 Human Inquiry
BSDBF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD44 Mouse CR3 Mouse Inquiry
BSTF-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD44 Mouse CR3 Mouse Inquiry
BSTF-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD44 Mouse CR3 Mouse Inquiry
BSCFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD44 Mouse CR3 Mouse Inquiry
BSCFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD44 Mouse CR3 Mouse Inquiry
MNAB-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Miniantibody) Human Miniantibody CD44 Mouse CR3 Mouse Inquiry
MNAB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Miniantibody) Human Miniantibody CD44 Mouse CR3 Mouse Inquiry
BSFC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD44 Mouse CR3 Mouse Inquiry
BSFC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD44 Mouse CR3 Mouse Inquiry
BSCC-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD44 Mouse CR3 Mouse Inquiry
BSCC-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD44 Mouse CR3 Mouse Inquiry
BIBD-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Bibody) Human Bibody CD44 Mouse CR3 Mouse Inquiry
BIBD-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Bibody) Human Bibody CD44 Mouse CR3 Mouse Inquiry
FABFV-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD44 Human CR3 Human Inquiry
FABFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD44 Mouse CR3 Mouse Inquiry
MiniB-H295 Recombinant Human Anti-CD44 x Human Anti-CR3 Bispecific Antibody (Minibody) Human Minibody CD44 Human CR3 Human Inquiry
MiniB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Minibody) Human Minibody CD44 Mouse CR3 Mouse Inquiry
SCTB-H185 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD44 Human CR3 Human Inquiry
SCDB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD44 Human CR3 Human Inquiry
FABIG-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD44 Human CR3 Human Inquiry
TRIB-H295 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD44 Human CR3 Human Inquiry
BSIG-H293 Human Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD44 Human CR3 Human Inquiry
CROSSAB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (CrossMab) Human CrossMab CD44 Human CR3 Human Inquiry
IGFV-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD44 Human CR3 Human Inquiry
BSDB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody) Human Diabody CD44 Human CR3 Human Inquiry
BSFAB-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD44 Human CR3 Human Inquiry
BSFV-H293 Recombinant Human Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD44 Human CR3 Human Inquiry
SCTB-090 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD44 Mouse CR3 Mouse Inquiry
SCDB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD44 Mouse CR3 Mouse Inquiry
FABIG-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD44 Mouse CR3 Mouse Inquiry
TRIB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD44 Mouse CR3 Mouse Inquiry
BSIG-121 Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD44 Mouse CR3 Mouse Inquiry
CROSSAB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (CrossMab) Human CrossMab CD44 Mouse CR3 Mouse Inquiry
IGFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD44 Mouse CR3 Mouse Inquiry
BSDB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Diabody) Human Diabody CD44 Mouse CR3 Mouse Inquiry
BSFAB-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD44 Mouse CR3 Mouse Inquiry
BSFV-121 Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD44 Mouse CR3 Mouse Inquiry

Background

Complement C3a Receptor 1 (CR3), also known as C3aR, is a G protein-coupled receptor that plays a significant role in the immune system. It primarily functions as the receptor for the complement component C3a, a key mediator of the complement system. Upon binding with C3a, CR3 triggers a signaling cascade within immune cells, leading to the modulation of inflammation, chemotaxis, and the release of inflammatory mediators. CR3 has diverse application fields because of its function on inflammatory and immune responses. It is studied in the context of several kinds of inflammatory illnesses, including allergic disorders, rheumatoid arthritis, and asthma. Furthermore, understanding the function and mechanism of CR3 can aid in the development of targeted therapies for modulating immune responses, inflammation-related disorders, and cancer.

C3a-C3a receptor axis in the TLR and inflammasome signaling cascades. (Ray, et al., 2018) Fig.1 C3a-C3a receptor axis in the TLR and inflammasome signaling cascades.1

Reference

  1. Ray, Tathagat Dutta, et al. “Species-specific differences in regulation of macrophage inflammation by the C3a-C3a receptor axis.” Innate immunity vol. 24,1 (2018): 66-78.
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