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CTLA4 & GLUT2 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H312 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CTLA4 Human GLUT2 Human Inquiry
T-BSDB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CTLA4 Mouse GLUT2 Mouse Inquiry
SCIGG-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scIgG) Human Single chain IgGs CTLA4 Human GLUT2 Human Inquiry
SCIGG-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scIgG) Human Single chain IgGs CTLA4 Mouse GLUT2 Mouse Inquiry
FVTIG-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CTLA4 Human GLUT2 Human Inquiry
FVTIG-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CTLA4 Mouse GLUT2 Mouse Inquiry
BSSG-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scFv-IgG) Human scFv-IgG CTLA4 Human GLUT2 Human Inquiry
BSSG-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-IgG) Human scFv-IgG CTLA4 Mouse GLUT2 Mouse Inquiry
IGLFV-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CTLA4 Human GLUT2 Human Inquiry
IGLFV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CTLA4 Mouse GLUT2 Mouse Inquiry
BSGV-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (IgG-Fv) Human IgG-Fv CTLA4 Mouse GLUT2 Mouse Inquiry
BSGV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (IgG-Fv) Human IgG-Fv CTLA4 Mouse GLUT2 Mouse Inquiry
BSDG-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Fv-IgG) Human Fv-IgG CTLA4 Human GLUT2 Human Inquiry
BSDG-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fv-IgG) Human Fv-IgG CTLA4 Mouse GLUT2 Mouse Inquiry
BABFV-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CTLA4 Human GLUT2 Human Inquiry
BABFV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CTLA4 Mouse GLUT2 Mouse Inquiry
FABVC-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CTLA4 Human GLUT2 Human Inquiry
FABVC-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CTLA4 Mouse GLUT2 Mouse Inquiry
SCDBC-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CTLA4 Human GLUT2 Human Inquiry
SCDBC-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CTLA4 Mouse GLUT2 Mouse Inquiry
BSDBC-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CTLA4 Human GLUT2 Human Inquiry
BSDBC-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CTLA4 Mouse GLUT2 Mouse Inquiry
SCDBF-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CTLA4 Human GLUT2 Human Inquiry
SCDBF-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CTLA4 Mouse GLUT2 Mouse Inquiry
BSFVF-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CTLA4 Human GLUT2 Human Inquiry
BSFVF-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CTLA4 Mouse GLUT2 Mouse Inquiry
BSDBF-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CTLA4 Human GLUT2 Human Inquiry
BSDBF-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CTLA4 Mouse GLUT2 Mouse Inquiry
BSTF-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CTLA4 Mouse GLUT2 Mouse Inquiry
BSTF-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CTLA4 Mouse GLUT2 Mouse Inquiry
BSCFV-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scFv-Fc) Human scFv-Fc CTLA4 Mouse GLUT2 Mouse Inquiry
BSCFV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-Fc) Human scFv-Fc CTLA4 Mouse GLUT2 Mouse Inquiry
MNAB-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Miniantibody) Human Miniantibody CTLA4 Mouse GLUT2 Mouse Inquiry
MNAB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Miniantibody) Human Miniantibody CTLA4 Mouse GLUT2 Mouse Inquiry
BSFC-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CTLA4 Mouse GLUT2 Mouse Inquiry
BSFC-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CTLA4 Mouse GLUT2 Mouse Inquiry
BSCC-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CTLA4 Mouse GLUT2 Mouse Inquiry
BSCC-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CTLA4 Mouse GLUT2 Mouse Inquiry
BIBD-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Bibody) Human Bibody CTLA4 Mouse GLUT2 Mouse Inquiry
BIBD-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Bibody) Human Bibody CTLA4 Mouse GLUT2 Mouse Inquiry
FABFV-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CTLA4 Human GLUT2 Human Inquiry
FABFV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CTLA4 Mouse GLUT2 Mouse Inquiry
MiniB-H314 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Bispecific Antibody (Minibody) Human Minibody CTLA4 Human GLUT2 Human Inquiry
MiniB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Minibody) Human Minibody CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-SAR024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-SAR006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-NGB024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-NGB006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-MEL024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-MEL006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-BGN024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-BGN006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-ABR024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-ABR006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-PAP024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-PAP006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-SAP024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-SAP006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-RTA024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-RTA006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-GEL024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-GEL006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-PE024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-PE006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-DT024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFAB-DT006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-SAR024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFV-SAR006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-NGB024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFV-NGB006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-MEL024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFV-MEL006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-BGN024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFV-BGN006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-ABR024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
BSFV-ABR006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-PAP024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human GLUT2 Human Inquiry
SCDB-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CTLA4 Human GLUT2 Human Inquiry
FABIG-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CTLA4 Human GLUT2 Human Inquiry
TRIB-H314 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CTLA4 Human GLUT2 Human Inquiry
BSIG-H312 Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CTLA4 Human GLUT2 Human Inquiry
CROSSAB-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (CrossMab) Human CrossMab CTLA4 Human GLUT2 Human Inquiry
IGFV-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CTLA4 Human GLUT2 Human Inquiry
BSDB-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Diabody) Human Diabody CTLA4 Human GLUT2 Human Inquiry
BSFAB-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CTLA4 Human GLUT2 Human Inquiry
BSFV-H312 Recombinant Human Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CTLA4 Human GLUT2 Human Inquiry
SCDB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CTLA4 Mouse GLUT2 Mouse Inquiry
FABIG-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CTLA4 Mouse GLUT2 Mouse Inquiry
TRIB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CTLA4 Mouse GLUT2 Mouse Inquiry
BSIG-145 Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CTLA4 Mouse GLUT2 Mouse Inquiry
CROSSAB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (CrossMab) Human CrossMab CTLA4 Mouse GLUT2 Mouse Inquiry
IGFV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CTLA4 Mouse GLUT2 Mouse Inquiry
BSDB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Diabody) Human Diabody CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CTLA4 Mouse GLUT2 Mouse Inquiry
BSFV-145 Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CTLA4 Mouse GLUT2 Mouse Inquiry
BSFAB-SAR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-NGB025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-NGB007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-MEL025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-MEL007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-BGN025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-BGN007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-ABR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-ABR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-PAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-PAP007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-SAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-SAP007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-RTA025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-RTA007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-GEL025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-GEL007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-PE025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-PE007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-DT025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-DT007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-SAR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-SAR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-NGB025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-NGB007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-MEL025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-MEL007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-BGN025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-BGN007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-ABR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-ABR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-PAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
SCDB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CTLA4 Human PD1 Human Inquiry
FABIG-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-IgG) Human Fab-IgG CTLA4 Human PD1 Human Inquiry
TRIB-H315 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CTLA4 Human PD1 Human Inquiry
BSIG-H313 Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CTLA4 Human PD1 Human Inquiry
CROSSAB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (CrossMab) Human CrossMab CTLA4 Human PD1 Human Inquiry
IGFV-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CTLA4 Human PD1 Human Inquiry
BSDB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Diabody) Human Diabody CTLA4 Human PD1 Human Inquiry
BSFAB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CTLA4 Human PD1 Human Inquiry
BSFV-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CTLA4 Human PD1 Human Inquiry
SCDB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CTLA4 Mouse PD1 Mouse Inquiry
FABIG-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-IgG) Human Fab-IgG CTLA4 Mouse PD1 Mouse Inquiry
TRIB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CTLA4 Mouse PD1 Mouse Inquiry
BSIG-146 Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CTLA4 Mouse PD1 Mouse Inquiry
CROSSAB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (CrossMab) Human CrossMab CTLA4 Mouse PD1 Mouse Inquiry
IGFV-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CTLA4 Mouse PD1 Mouse Inquiry
BSDB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Diabody) Human Diabody CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CTLA4 Mouse PD1 Mouse Inquiry
BSFV-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CTLA4 Mouse PD1 Mouse Inquiry

Background

CTLA-4 is a T-cell activation inhibitor. It inhibits the activation of T cells by competitively binding with the co-stimulatory molecule CD28. Anti-CTLA-4 has been demonstrated to cause antagonistic effects that contribute to increased autoimmunity. Glucose transporter 2 (GLUT2) is a transmembrane protein found mostly on the surface of pancreatic β-cells. It is responsible for passive glucose transport. CTLA4 combined with GLUT2 can be developed as a new bispecific antibody (BsAb), which is a possible strategy for Type 1 diabetes mellitus (T1D)-targeted treatment. An agonistic mAb against CTLA-4 is used as the treatment arm. GLUT2 serves as an anchor on pancreatic β-cells for BsAb, as it is not a target of the autoimmune attack in T1D.

Fig.1 The roles of CTLA4 and GLUT2 in Anti-Tumor-Immune Response. (Kouidhi, et al,2017) Fig.1 Anti-Tumor-Immune Response.1

Reference

  1. Kouidhi, Soumaya, Amel Benammar Elgaaied, and Salem Chouaib. "Impact of metabolism on T-cell differentiation and function and cross talk with tumor microenvironment." Frontiers in Immunology 8 (2017): 270.
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