Home > Products > By Targets > DKK1 & SOST
DKK1 & SOST Bispecific Antibodies
Product List Background

Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
T-BSDB-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem Diabody) Human DKK1 SOST Inquiry
T-BSDB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem Diabody) Human DKK1 SOST Inquiry
SCIGG-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scIgG) Human Single chain IgGs DKK1 SOST Inquiry
SCIGG-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scIgG) Human Single chain IgGs DKK1 SOST Inquiry
FVTIG-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scFv4-Ig) Human Appended IgGs DKK1 SOST Inquiry
FVTIG-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv4-Ig) Human Appended IgGs DKK1 SOST Inquiry
BSSG-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scFv-IgG) Human Appended IgGs DKK1 SOST Inquiry
BSSG-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv-IgG) Human Appended IgGs DKK1 SOST Inquiry
IGLFV-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs DKK1 SOST Inquiry
IGLFV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG(L)-scFv) Human Appended IgGs DKK1 SOST Inquiry
BSGV-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (IgG-Fv) Human IgG-Fv DKK1 SOST Inquiry
BSGV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG-Fv) Human IgG-Fv DKK1 SOST Inquiry
BSDG-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Fv-IgG) Human Appended IgGs DKK1 SOST Inquiry
BSDG-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fv-IgG) Human Appended IgGs DKK1 SOST Inquiry
BABFV-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins DKK1 SOST Inquiry
BABFV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (F(ab')2-scFv2) Human Fab-Fc Fusion Proteins DKK1 SOST Inquiry
FABVC-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins DKK1 SOST Inquiry
FABVC-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-scFv-Fc) Human Fab-Fc Fusion Proteins DKK1 SOST Inquiry
SCDBC-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
SCDBC-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scDiabody-CH3) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSDBC-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSDBC-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Diabody-CH3) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
SCDBF-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
SCDBF-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scDiabody-Fc) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSFVF-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSFVF-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem scFv-Fc) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSDBF-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSDBF-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Diabody-Fc) Human Constant Domain-extended Bispecific Fragments DKK1 SOST Inquiry
BSTF-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSTF-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv-Fc-scFv) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSCFV-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSCFV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv-Fc) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
MNAB-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
MNAB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Miniantibody) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSFC-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSFC-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv-CH3) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSCC-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BSCC-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (scFv-CH1/CL) Human scFv-based Bispecific Fragments DKK1 SOST Inquiry
BIBD-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Bibody) Human Bibody DKK1 SOST Inquiry
BIBD-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Bibody) Human Bibody DKK1 SOST Inquiry
FABFV-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Fab-Fv) Human Fab-Fv DKK1 SOST Inquiry
FABFV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-Fv) Human Fab-Fv DKK1 SOST Inquiry
MiniB-H317 Recombinant Human Anti-DKK1 x Human Anti-SOST Bispecific Antibody (Minibody) Human Minibody DKK1 SOST Inquiry
MiniB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Minibody) Human Minibody DKK1 SOST Inquiry
SCDB-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody DKK1 SOST Inquiry
FABIG-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-IgG) Human Fab-IgG DKK1 SOST Inquiry
TRIB-H317 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Triple Body) Human Triple Body DKK1 SOST Inquiry
BSIG-H315 Human Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG-IgG) Human IgG-IgG DKK1 SOST Inquiry
CROSSAB-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (CrossMab) Human CrossMab DKK1 SOST Inquiry
IGFV-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG-scFv) Human IgG-scFv DKK1 SOST Inquiry
BSDB-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Diabody) Human Diabody DKK1 SOST Inquiry
BSFAB-H315 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem Fab) Human Tandem Fab DKK1 SOST Inquiry
BSFV-H314 Recombinant Human Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem scFv) Human Tandem scFv DKK1 SOST Inquiry
SCDB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody DKK1 SOST Inquiry
FABIG-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Fab-IgG) Human Fab-IgG DKK1 SOST Inquiry
TRIB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Triple Body) Human Triple Body DKK1 SOST Inquiry
BSIG-148 Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG-IgG) Human IgG-IgG DKK1 SOST Inquiry
CROSSAB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (CrossMab) Human CrossMab DKK1 SOST Inquiry
IGFV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (IgG-scFv) Human IgG-scFv DKK1 SOST Inquiry
BSDB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Diabody) Human Diabody DKK1 SOST Inquiry
BSFAB-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem Fab) Human Tandem Fab DKK1 SOST Inquiry
BSFV-148 Recombinant Anti-DKK1 x Anti-SOST Bispecific Antibody (Tandem scFv) Human Tandem scFv DKK1 SOST Inquiry

Background

Dickkopf-1 (DKK-1) and SOST are two molecules that prevent the formation of new bone cells and bone growth. Research has shown that when both DKK-1 and SOST are blocked, there is a strong positive effect on bone formation in animals like rodents and non-human primates. Scientists have created a special type of antibody that targets both DKK-1 and SOST, and when this antibody is given to mice with intact bones or rats with fractured bones, it leads to significant increases in bone formation, bone density, and bone strength. The antibody also outperforms other treatments in promoting bone repair by targeting different aspects of the healing process. As a result, developing antibodies that target both DKK1 and SOST shed light on the development of skeletal therapies.

Fig. 1 A bispecific antibody that targets DKK1 and SOST. (Florio, et al., 2016) Fig. 1 Structure of an engineered bispecific antibody targeting DKK1 and SOST.1

Reference

  1. Florio, Monica, et al. "A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair." Nature Communications 7 (2016): 11505.
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related Sections

SERVICES

PRODUCTS

PLATFORMS

quality
ISO 9001 Certified - Creative Biolabs Quality Management System.
© 2025 Creative Biolabs. All Rights Reserved.