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FGFR1 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H326 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Tandem Diabody) Human Tandem Diabody FGFR1 Human KLB Human Inquiry
T-BSDB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Tandem Diabody) Human Tandem Diabody FGFR1 Mouse KLB Mouse Inquiry
SCIGG-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scIgG) Human Single chain IgGs FGFR1 Human KLB Human Inquiry
SCIGG-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scIgG) Human Single chain IgGs FGFR1 Mouse KLB Mouse Inquiry
FVTIG-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scFv4-Ig) Human scFv4-Ig FGFR1 Human KLB Human Inquiry
FVTIG-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv4-Ig) Human scFv4-Ig FGFR1 Mouse KLB Mouse Inquiry
BSSG-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scFv-IgG) Human scFv-IgG FGFR1 Human KLB Human Inquiry
BSSG-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-IgG) Human scFv-IgG FGFR1 Mouse KLB Mouse Inquiry
IGLFV-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv FGFR1 Human KLB Human Inquiry
IGLFV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv FGFR1 Mouse KLB Mouse Inquiry
BSGV-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (IgG-Fv) Human IgG-Fv FGFR1 Mouse KLB Mouse Inquiry
BSGV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (IgG-Fv) Human IgG-Fv FGFR1 Mouse KLB Mouse Inquiry
BSDG-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Fv-IgG) Human Fv-IgG FGFR1 Human KLB Human Inquiry
BSDG-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fv-IgG) Human Fv-IgG FGFR1 Mouse KLB Mouse Inquiry
BABFV-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 FGFR1 Human KLB Human Inquiry
BABFV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 FGFR1 Mouse KLB Mouse Inquiry
FABVC-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc FGFR1 Human KLB Human Inquiry
FABVC-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc FGFR1 Mouse KLB Mouse Inquiry
SCDBC-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 FGFR1 Human KLB Human Inquiry
SCDBC-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 FGFR1 Mouse KLB Mouse Inquiry
BSDBC-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 FGFR1 Human KLB Human Inquiry
BSDBC-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 FGFR1 Mouse KLB Mouse Inquiry
SCDBF-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc FGFR1 Human KLB Human Inquiry
SCDBF-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc FGFR1 Mouse KLB Mouse Inquiry
BSFVF-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc FGFR1 Human KLB Human Inquiry
BSFVF-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc FGFR1 Mouse KLB Mouse Inquiry
BSDBF-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Diabody-Fc) Human Diabody-Fc FGFR1 Human KLB Human Inquiry
BSDBF-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody-Fc) Human Diabody-Fc FGFR1 Mouse KLB Mouse Inquiry
BSTF-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv FGFR1 Mouse KLB Mouse Inquiry
BSTF-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv FGFR1 Mouse KLB Mouse Inquiry
BSCFV-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scFv-Fc) Human scFv-Fc FGFR1 Mouse KLB Mouse Inquiry
BSCFV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-Fc) Human scFv-Fc FGFR1 Mouse KLB Mouse Inquiry
MNAB-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Miniantibody) Human Miniantibody FGFR1 Mouse KLB Mouse Inquiry
MNAB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Miniantibody) Human Miniantibody FGFR1 Mouse KLB Mouse Inquiry
BSFC-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scFv-CH3) Human scFv-CH3 FGFR1 Mouse KLB Mouse Inquiry
BSFC-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-CH3) Human scFv-CH3 FGFR1 Mouse KLB Mouse Inquiry
BSCC-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL FGFR1 Mouse KLB Mouse Inquiry
BSCC-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL FGFR1 Mouse KLB Mouse Inquiry
BIBD-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Bibody) Human Bibody FGFR1 Mouse KLB Mouse Inquiry
BIBD-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Bibody) Human Bibody FGFR1 Mouse KLB Mouse Inquiry
FABFV-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Fab-Fv) Human Fab-Fv FGFR1 Human KLB Human Inquiry
FABFV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fab-Fv) Human Fab-Fv FGFR1 Mouse KLB Mouse Inquiry
MiniB-H327 Recombinant Human Anti-FGFR1 x Human Anti-KLB Bispecific Antibody (Minibody) Human Minibody FGFR1 Human KLB Human Inquiry
MiniB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Minibody) Human Minibody FGFR1 Mouse KLB Mouse Inquiry
SCDB-H326 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody FGFR1 Human KLB Human Inquiry
FABIG-H326 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fab-IgG) Human Fab-IgG FGFR1 Human KLB Human Inquiry
TRIB-H328 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv FGFR1 Human KLB Human Inquiry
BSIG-H326 Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (IgG-IgG) Human IgG-IgG FGFR1 Human KLB Human Inquiry
CROSSAB-H326 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (CrossMab) Human CrossMab FGFR1 Human KLB Human Inquiry
IGFV-H326 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (IgG-scFv) Human IgG-scFv FGFR1 Human KLB Human Inquiry
BSDB-H326 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody) Human Diabody FGFR1 Human KLB Human Inquiry
BSFAB-H326 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (Tandem Fab) Human Tandem Fab FGFR1 Human KLB Human Inquiry
BSFV-H324 Recombinant Human Anti-FGFR1 x Anti-KLB Bispecific Antibody (Tandem scFv) Human Tandem scFv FGFR1 Human KLB Human Inquiry
SCDB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody FGFR1 Mouse KLB Mouse Inquiry
FABIG-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fab-IgG) Human Fab-IgG FGFR1 Mouse KLB Mouse Inquiry
TRIB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv FGFR1 Mouse KLB Mouse Inquiry
BSIG-161 Anti-FGFR1 x Anti-KLB Bispecific Antibody (IgG-IgG) Human IgG-IgG FGFR1 Mouse KLB Mouse Inquiry
CROSSAB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (CrossMab) Human CrossMab FGFR1 Mouse KLB Mouse Inquiry
IGFV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (IgG-scFv) Human IgG-scFv FGFR1 Mouse KLB Mouse Inquiry
BSDB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Diabody) Human Diabody FGFR1 Mouse KLB Mouse Inquiry
BSFAB-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Tandem Fab) Human Tandem Fab FGFR1 Mouse KLB Mouse Inquiry
BSFV-161 Recombinant Anti-FGFR1 x Anti-KLB Bispecific Antibody (Tandem scFv) Human Tandem scFv FGFR1 Mouse KLB Mouse Inquiry

Background

FGFR1 (fibroblast growth factor receptor 1), alias CD331, is a single-pass transmembrane protein characterized by three domains: an intracellular tyrosine kinase domain, an extracellular domain, and a transmembrane domain. FGFR1 functions as a receptor tyrosine kinase, with its ligand FGF belonging to the fibroblast growth factor family. The FGFR/FGF signaling pathway actively participates in essential cellular processes, including cell proliferation, differentiation, and cellular lineage commitment, exerting influence across a spectrum of biological events. Current research highlights the significance of the FGFR1 gene in organ development and the pathophysiology of various diseases. Therapeutic interventions involving agonists and antagonists targeting this pathway show promise in addressing disorders associated with FGF signaling dysregulation.

The schema diagram of classical FGF/FGFR pathways. (Xie, et al., 2020) Fig.1 The schema diagram of classical FGF/FGFR pathways.1

Reference

  1. Xie, Yangli, et al. "FGF/FGFR signaling in health and disease." Signal transduction and targeted therapy 5.1 (2020): 181.
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