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HER1 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H329 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody HER1 Human HER3 Human Inquiry
T-BSDB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody HER1 Mouse HER3 Mouse Inquiry
SCIGG-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scIgG) Human Single chain IgGs HER1 Human HER3 Human Inquiry
SCIGG-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scIgG) Human Single chain IgGs HER1 Mouse HER3 Mouse Inquiry
FVTIG-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig HER1 Human HER3 Human Inquiry
FVTIG-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig HER1 Mouse HER3 Mouse Inquiry
BSSG-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scFv-IgG) Human scFv-IgG HER1 Human HER3 Human Inquiry
BSSG-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scFv-IgG) Human scFv-IgG HER1 Mouse HER3 Mouse Inquiry
IGLFV-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv HER1 Human HER3 Human Inquiry
IGLFV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv HER1 Mouse HER3 Mouse Inquiry
BSGV-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (IgG-Fv) Human IgG-Fv HER1 Mouse HER3 Mouse Inquiry
BSGV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (IgG-Fv) Human IgG-Fv HER1 Mouse HER3 Mouse Inquiry
BSDG-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Fv-IgG) Human Fv-IgG HER1 Human HER3 Human Inquiry
BSDG-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fv-IgG) Human Fv-IgG HER1 Mouse HER3 Mouse Inquiry
BABFV-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 HER1 Human HER3 Human Inquiry
BABFV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 HER1 Mouse HER3 Mouse Inquiry
FABVC-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc HER1 Human HER3 Human Inquiry
FABVC-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc HER1 Mouse HER3 Mouse Inquiry
SCDBC-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 HER1 Human HER3 Human Inquiry
SCDBC-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 HER1 Mouse HER3 Mouse Inquiry
BSDBC-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 HER1 Human HER3 Human Inquiry
BSDBC-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 HER1 Mouse HER3 Mouse Inquiry
SCDBF-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc HER1 Human HER3 Human Inquiry
SCDBF-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc HER1 Mouse HER3 Mouse Inquiry
BSFVF-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc HER1 Human HER3 Human Inquiry
BSFVF-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc HER1 Mouse HER3 Mouse Inquiry
BSDBF-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc HER1 Human HER3 Human Inquiry
BSDBF-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc HER1 Mouse HER3 Mouse Inquiry
BSTF-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv HER1 Mouse HER3 Mouse Inquiry
BSTF-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv HER1 Mouse HER3 Mouse Inquiry
BSCFV-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scFv-Fc) Human scFv-Fc HER1 Mouse HER3 Mouse Inquiry
BSCFV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scFv-Fc) Human scFv-Fc HER1 Mouse HER3 Mouse Inquiry
MNAB-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Miniantibody) Human Miniantibody HER1 Mouse HER3 Mouse Inquiry
MNAB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Miniantibody) Human Miniantibody HER1 Mouse HER3 Mouse Inquiry
BSFC-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scFv-CH3) Human scFv-CH3 HER1 Mouse HER3 Mouse Inquiry
BSFC-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scFv-CH3) Human scFv-CH3 HER1 Mouse HER3 Mouse Inquiry
BSCC-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL HER1 Mouse HER3 Mouse Inquiry
BSCC-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL HER1 Mouse HER3 Mouse Inquiry
BIBD-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Bibody) Human Bibody HER1 Mouse HER3 Mouse Inquiry
BIBD-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Bibody) Human Bibody HER1 Mouse HER3 Mouse Inquiry
FABFV-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Fab-Fv) Human Fab-Fv HER1 Human HER3 Human Inquiry
FABFV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fab-Fv) Human Fab-Fv HER1 Mouse HER3 Mouse Inquiry
MiniB-H330 Recombinant Human Anti-HER1 x Human Anti-HER3 Bispecific Antibody (Minibody) Human Minibody HER1 Human HER3 Human Inquiry
MiniB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Minibody) Human Minibody HER1 Mouse HER3 Mouse Inquiry
BSFAB-SAR031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-SAR013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-NGB031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-NGB013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-MEL031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-MEL013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-BGN031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-BGN013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-ABR031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-ABR013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-PAP031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-PAP013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-SAP031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-SAP013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-RTA031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-RTA013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-GEL031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-GEL013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-PE031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-PE013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFAB-DT031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFAB-DT013 Recombinant Anti-HER1 x Anti-HER3 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFV-SAR031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFV-SAR013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFV-NGB031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFV-NGB013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFV-MEL031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFV-MEL013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFV-BGN031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFV-BGN013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFV-ABR031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFV-ABR013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
BSFV-PAP031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Human HER3 Human Inquiry
BSFV-PAP013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 Mouse HER3 Mouse Inquiry
SCDB-H329 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody HER1 Human HER3 Human Inquiry
FABIG-H329 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (Fab-IgG) Human Fab-IgG HER1 Human HER3 Human Inquiry
TRIB-H331 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv HER1 Human HER3 Human Inquiry
BSIG-H329 Human Anti-HER1 x Anti-HER3 Bispecific Antibody (IgG-IgG) Human IgG-IgG HER1 Human HER3 Human Inquiry
CROSSAB-H329 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (CrossMab) Human CrossMab HER1 Human HER3 Human Inquiry
IGFV-H329 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (IgG-scFv) Human IgG-scFv HER1 Human HER3 Human Inquiry
BSDB-H329 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (Diabody) Human Diabody HER1 Human HER3 Human Inquiry
BSFAB-H329 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (Tandem Fab) Human Tandem Fab HER1 Human HER3 Human Inquiry
BSFV-H327 Recombinant Human Anti-HER1 x Anti-HER3 Bispecific Antibody (Tandem scFv) Human Tandem scFv HER1 Human HER3 Human Inquiry
SCDB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody HER1 Mouse HER3 Mouse Inquiry
FABIG-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fab-IgG) Human Fab-IgG HER1 Mouse HER3 Mouse Inquiry
TRIB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv HER1 Mouse HER3 Mouse Inquiry
BSIG-165 Anti-HER1 x Anti-HER3 Bispecific Antibody (IgG-IgG) Human IgG-IgG HER1 Mouse HER3 Mouse Inquiry
CROSSAB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (CrossMab) Human CrossMab HER1 Mouse HER3 Mouse Inquiry
IGFV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (IgG-scFv) Human IgG-scFv HER1 Mouse HER3 Mouse Inquiry
BSDB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Diabody) Human Diabody HER1 Mouse HER3 Mouse Inquiry
BSFAB-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Tandem Fab) Human Tandem Fab HER1 Mouse HER3 Mouse Inquiry
BSFV-165 Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Tandem scFv) Human Tandem scFv HER1 Mouse HER3 Mouse Inquiry

Background

HER1, a transmembrane glycoprotein belonging to the epidermal growth factor family, is a receptor tyrosine kinase commonly known as EGFR. Located on the cell surface, EGFR binds to EGF, inducing tyrosine autophosphorylation and receptor dimerization, initiating several signal transduction cascades, principally the JNK, Akt and MAPK pathways, resulting in DNA synthesis and cell proliferation. Recent studies indicate that the activation of HER1 contributes to the development and progression of renal diseases in animal models of diabetic nephropathy and glomerulonephritis, the behind biochemical mechanisms associated with the induction of tubular atrophy, activation of renal interstitial fibroblasts, overproduction of inflammatory factors, and/or promotion of glomerular and vascular injury. Moreover, HER1 is also identified as a significant treatment target for COVID-19 infection with SARS-CoV-2.

The transactivation of EGFR results in downstream signal pathways. (Tang, et al., 2013) Fig.1 The transactivation of EGFR results in downstream signal pathways.1

Reference

  1. Tang, Jinhua, Na Liu, and Shougang Zhuang. "Role of epidermal growth factor receptor in acute and chronic kidney injury." Kidney international 83.5 (2013): 804-810.
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