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HSG & TROP2 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H334 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody HSG Human TROP2 Human Inquiry
T-BSDB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody HSG Mouse TROP2 Mouse Inquiry
SCIGG-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scIgG) Human Single chain IgGs HSG Human TROP2 Human Inquiry
SCIGG-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scIgG) Human Single chain IgGs HSG Mouse TROP2 Mouse Inquiry
FVTIG-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig HSG Human TROP2 Human Inquiry
FVTIG-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig HSG Mouse TROP2 Mouse Inquiry
BSSG-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scFv-IgG) Human scFv-IgG HSG Human TROP2 Human Inquiry
BSSG-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-IgG) Human scFv-IgG HSG Mouse TROP2 Mouse Inquiry
IGLFV-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv HSG Human TROP2 Human Inquiry
IGLFV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv HSG Mouse TROP2 Mouse Inquiry
BSGV-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (IgG-Fv) Human IgG-Fv HSG Human TROP2 Human Inquiry
BSGV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (IgG-Fv) Human IgG-Fv HSG Mouse TROP2 Mouse Inquiry
BSDG-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Fv-IgG) Human Fv-IgG HSG Human TROP2 Human Inquiry
BSDG-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Fv-IgG) Human Fv-IgG HSG Mouse TROP2 Mouse Inquiry
BABFV-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 HSG Human TROP2 Human Inquiry
BABFV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 HSG Mouse TROP2 Mouse Inquiry
FABVC-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc HSG Human TROP2 Human Inquiry
FABVC-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc HSG Mouse TROP2 Mouse Inquiry
SCDBC-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 HSG Human TROP2 Human Inquiry
SCDBC-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 HSG Mouse TROP2 Mouse Inquiry
BSDBC-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 HSG Human TROP2 Human Inquiry
BSDBC-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 HSG Mouse TROP2 Mouse Inquiry
SCDBF-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc HSG Human TROP2 Human Inquiry
SCDBF-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc HSG Mouse TROP2 Mouse Inquiry
BSFVF-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc HSG Human TROP2 Human Inquiry
BSFVF-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc HSG Mouse TROP2 Mouse Inquiry
BSDBF-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc HSG Human TROP2 Human Inquiry
BSDBF-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc HSG Mouse TROP2 Mouse Inquiry
BSTF-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv HSG Human TROP2 Human Inquiry
BSTF-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv HSG Mouse TROP2 Mouse Inquiry
BSCFV-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scFv-Fc) Human scFv-Fc HSG Human TROP2 Human Inquiry
BSCFV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-Fc) Human scFv-Fc HSG Mouse TROP2 Mouse Inquiry
MNAB-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Miniantibody) Human Miniantibody HSG Human TROP2 Human Inquiry
MNAB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Miniantibody) Human Miniantibody HSG Mouse TROP2 Mouse Inquiry
BSFC-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scFv-CH3) Human scFv-CH3 HSG Human TROP2 Human Inquiry
BSFC-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-CH3) Human scFv-CH3 HSG Mouse TROP2 Mouse Inquiry
BSCC-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL HSG Human TROP2 Human Inquiry
BSCC-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL HSG Mouse TROP2 Mouse Inquiry
BIBD-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Bibody) Human Bibody HSG Human TROP2 Human Inquiry
BIBD-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Bibody) Human Bibody HSG Mouse TROP2 Mouse Inquiry
FABFV-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Fab-Fv) Human Fab-Fv HSG Human TROP2 Human Inquiry
FABFV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Fab-Fv) Human Fab-Fv HSG Mouse TROP2 Mouse Inquiry
MiniB-H335 Recombinant Human Anti-HSG x Human Anti-TROP2 Bispecific Antibody (Minibody) Human Minibody HSG Human TROP2 Human Inquiry
MiniB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Minibody) Human Minibody HSG Mouse TROP2 Mouse Inquiry
SCDB-H334 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody HSG Human TROP2 Human Inquiry
FABIG-H334 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (Fab-IgG) Human Fab-IgG HSG Human TROP2 Human Inquiry
TRIB-H336 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv HSG Human TROP2 Human Inquiry
BSIG-H334 Human Anti-HSG x Anti-TROP2 Bispecific Antibody (IgG-IgG) Human IgG-IgG HSG Human TROP2 Human Inquiry
CROSSAB-H334 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (CrossMab) Human CrossMab HSG Human TROP2 Human Inquiry
IGFV-H334 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (IgG-scFv) Human IgG-scFv HSG Human TROP2 Human Inquiry
BSDB-H334 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (Diabody) Human Diabody HSG Human TROP2 Human Inquiry
BSFAB-H334 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem Fab) Human Tandem Fab HSG Human TROP2 Human Inquiry
BSFV-H332 Recombinant Human Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem scFv) Human Tandem scFv HSG Human TROP2 Human Inquiry
SCDB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody HSG Mouse TROP2 Mouse Inquiry
FABIG-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Fab-IgG) Human Fab-IgG HSG Mouse TROP2 Mouse Inquiry
TRIB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv HSG Mouse TROP2 Mouse Inquiry
BSIG-170 Anti-HSG x Anti-TROP2 Bispecific Antibody (IgG-IgG) Human IgG-IgG HSG Mouse TROP2 Mouse Inquiry
CROSSAB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (CrossMab) Human CrossMab HSG Mouse TROP2 Mouse Inquiry
IGFV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (IgG-scFv) Human IgG-scFv HSG Mouse TROP2 Mouse Inquiry
BSDB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Diabody) Human Diabody HSG Mouse TROP2 Mouse Inquiry
BSFAB-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem Fab) Human Tandem Fab HSG Mouse TROP2 Mouse Inquiry
BSFV-170 Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Tandem scFv) Human Tandem scFv HSG Mouse TROP2 Mouse Inquiry
BSCC-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CEA Mouse HSG Mouse Inquiry
BSCC-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse TROP2 Mouse Inquiry
BIBD-H329 Recombinant Human Anti-FN1 x Human Anti-HSG Bispecific Antibody (Bibody) Human Bibody FN1 Human HSG Human Inquiry
BIBD-H310 Recombinant Human Anti-CEA x Human Anti-HSG Bispecific Antibody (Bibody) Human Bibody CEA Human HSG Human Inquiry
BIBD-H283 Recombinant Human Anti-CD3 x Human Anti-TROP2 Bispecific Antibody (Bibody) Human Bibody CD3 Human TROP2 Human Inquiry
BIBD-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Bibody) Human Bibody FN1 Mouse HSG Mouse Inquiry
BIBD-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Bibody) Human Bibody CEA Mouse HSG Mouse Inquiry
BIBD-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Bibody) Human Bibody CD3 Mouse TROP2 Mouse Inquiry
FABFV-H329 Recombinant Human Anti-FN1 x Human Anti-HSG Bispecific Antibody (Fab-Fv) Human Fab-Fv FN1 Human HSG Human Inquiry
FABFV-H310 Recombinant Human Anti-CEA x Human Anti-HSG Bispecific Antibody (Fab-Fv) Human Fab-Fv CEA Human HSG Human Inquiry
FABFV-H283 Recombinant Human Anti-CD3 x Human Anti-TROP2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human TROP2 Human Inquiry
FABFV-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Fab-Fv) Human Fab-Fv FN1 Mouse HSG Mouse Inquiry
FABFV-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Fab-Fv) Human Fab-Fv CEA Mouse HSG Mouse Inquiry
FABFV-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse TROP2 Mouse Inquiry
MiniB-H329 Recombinant Human Anti-FN1 x Human Anti-HSG Bispecific Antibody (Minibody) Human Minibody FN1 Human HSG Human Inquiry
MiniB-H310 Recombinant Human Anti-CEA x Human Anti-HSG Bispecific Antibody (Minibody) Human Minibody CEA Human HSG Human Inquiry
MiniB-H283 Recombinant Human Anti-CD3 x Human Anti-TROP2 Bispecific Antibody (Minibody) Human Minibody CD3 Human TROP2 Human Inquiry
MiniB-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Minibody) Human Minibody FN1 Mouse HSG Mouse Inquiry
MiniB-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Minibody) Human Minibody CEA Mouse HSG Mouse Inquiry
MiniB-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Minibody) Human Minibody CD3 Mouse TROP2 Mouse Inquiry
SCTB-H176 Recombinant Human Anti-TROP2 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human TROP2 Human Inquiry
SCDB-H328 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody FN1 Human HSG Human Inquiry
SCDB-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CEA Human HSG Human Inquiry
SCDB-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human TROP2 Human Inquiry
FABIG-H328 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (Fab-IgG) Human Fab-IgG FN1 Human HSG Human Inquiry
FABIG-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (Fab-IgG) Human Fab-IgG CEA Human HSG Human Inquiry
FABIG-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human TROP2 Human Inquiry
TRIB-H330 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv FN1 Human HSG Human Inquiry
TRIB-H310 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CEA Human HSG Human Inquiry
TRIB-H283 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human TROP2 Human Inquiry
BSIG-H328 Human Anti-FN1 x Anti-HSG Bispecific Antibody (IgG-IgG) Human IgG-IgG FN1 Human HSG Human Inquiry
BSIG-H308 Human Anti-CEA x Anti-HSG Bispecific Antibody (IgG-IgG) Human IgG-IgG CEA Human HSG Human Inquiry
BSIG-H281 Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human TROP2 Human Inquiry
CROSSAB-H328 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (CrossMab) Human CrossMab FN1 Human HSG Human Inquiry
CROSSAB-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (CrossMab) Human CrossMab CEA Human HSG Human Inquiry
CROSSAB-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human TROP2 Human Inquiry
IGFV-H328 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (IgG-scFv) Human IgG-scFv FN1 Human HSG Human Inquiry
IGFV-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (IgG-scFv) Human IgG-scFv CEA Human HSG Human Inquiry
IGFV-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human TROP2 Human Inquiry
BSDB-H328 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (Diabody) Human Diabody FN1 Human HSG Human Inquiry
BSDB-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (Diabody) Human Diabody CEA Human HSG Human Inquiry
BSDB-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (Diabody) Human Diabody CD3 Human TROP2 Human Inquiry
BSFAB-H328 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (Tandem Fab) Human Tandem Fab FN1 Human HSG Human Inquiry
BSFAB-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (Tandem Fab) Human Tandem Fab CEA Human HSG Human Inquiry
BSFAB-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human TROP2 Human Inquiry
BSFV-H326 Recombinant Human Anti-FN1 x Anti-HSG Bispecific Antibody (Tandem scFv) Human Tandem scFv FN1 Human HSG Human Inquiry
BSFV-H308 Recombinant Human Anti-CEA x Anti-HSG Bispecific Antibody (Tandem scFv) Human Tandem scFv CEA Human HSG Human Inquiry
BSFV-H281 Recombinant Human Anti-CD3 x Anti-TROP2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human TROP2 Human Inquiry
SCTB-080 Recombinant Anti-TROP2 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse TROP2 Mouse Inquiry
SCDB-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody FN1 Mouse HSG Mouse Inquiry
SCDB-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CEA Mouse HSG Mouse Inquiry
SCDB-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse TROP2 Mouse Inquiry
FABIG-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Fab-IgG) Human Fab-IgG FN1 Mouse HSG Mouse Inquiry
FABIG-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Fab-IgG) Human Fab-IgG CEA Mouse HSG Mouse Inquiry
FABIG-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse TROP2 Mouse Inquiry
TRIB-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv FN1 Mouse HSG Mouse Inquiry
TRIB-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CEA Mouse HSG Mouse Inquiry
TRIB-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse TROP2 Mouse Inquiry
BSIG-163 Anti-FN1 x Anti-HSG Bispecific Antibody (IgG-IgG) Human IgG-IgG FN1 Mouse HSG Mouse Inquiry
BSIG-140 Anti-CEA x Anti-HSG Bispecific Antibody (IgG-IgG) Human IgG-IgG CEA Mouse HSG Mouse Inquiry
BSIG-107 Anti-CD3 x Anti-TROP2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse TROP2 Mouse Inquiry
CROSSAB-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (CrossMab) Human CrossMab FN1 Mouse HSG Mouse Inquiry
CROSSAB-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (CrossMab) Human CrossMab CEA Mouse HSG Mouse Inquiry
CROSSAB-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse TROP2 Mouse Inquiry
IGFV-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (IgG-scFv) Human IgG-scFv FN1 Mouse HSG Mouse Inquiry
IGFV-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (IgG-scFv) Human IgG-scFv CEA Mouse HSG Mouse Inquiry
IGFV-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse TROP2 Mouse Inquiry
BSDB-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Diabody) Human Diabody FN1 Mouse HSG Mouse Inquiry
BSDB-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Diabody) Human Diabody CEA Mouse HSG Mouse Inquiry
BSDB-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse TROP2 Mouse Inquiry
BSFAB-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Tandem Fab) Human Tandem Fab FN1 Mouse HSG Mouse Inquiry
BSFAB-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Tandem Fab) Human Tandem Fab CEA Mouse HSG Mouse Inquiry
BSFAB-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse TROP2 Mouse Inquiry
BSFV-163 Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Tandem scFv) Human Tandem scFv FN1 Mouse HSG Mouse Inquiry
BSFV-140 Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (Tandem scFv) Human Tandem scFv CEA Mouse HSG Mouse Inquiry
BSFV-107 Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse TROP2 Mouse Inquiry

Background

In the development and progression of tumors, HSG and TROP2 play crucial and complementary roles. HSG (Tumor-Specific Growth Factor) significantly regulates cell proliferation and apoptosis, especially in certain types of cancer. It primarily controls cell growth by affecting intracellular signaling pathways, such as by inhibiting cyclin-dependent kinases. TROP2, a cell surface glycoprotein, is closely associated with cell proliferation, migration, and tumor invasiveness. It affects the actions of tumor cells by stimulating a variety of signaling routes, notably PI3K/AKT and MAPK. Therefore, applying bispecific antibodies targeting both HSG and TROP2 in therapeutic strategies can effectively control both the proliferation and invasive behavior of tumor cells, providing a more comprehensive approach to research on cancer treatment.

Fig.1 Pathways involving Trop2 on the membrane. (Shvartsur & Bonavida, 2015) Fig.1 mTrop2 Cell Signaling and Resulting Activities.1

Reference

  1. Shvartsur, A.; Bonavida, B. Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. Genes Cancer. 2015, 6(3-4):84-105.
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