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IL13 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
BSDG-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Fv-IgG) Human Fv-IgG IL13 Human IL4 Human Inquiry
BSDG-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Fv-IgG) Human Fv-IgG IL13 Human IL17 Human Inquiry
BSDG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fv-IgG) Human Fv-IgG IL13 Mouse IL4 Mouse Inquiry
BSDG-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Fv-IgG) Human Fv-IgG IL13 Mouse IL17 Mouse Inquiry
BABFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 IL13 Human IL4 Human Inquiry
BABFV-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 IL13 Human IL17 Human Inquiry
BABFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 IL13 Mouse IL4 Mouse Inquiry
BABFV-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 IL13 Mouse IL17 Mouse Inquiry
FABVC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc IL13 Human IL4 Human Inquiry
FABVC-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc IL13 Human IL17 Human Inquiry
FABVC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc IL13 Mouse IL4 Mouse Inquiry
FABVC-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc IL13 Mouse IL17 Mouse Inquiry
SCDBC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 IL13 Human IL4 Human Inquiry
SCDBC-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 IL13 Human IL17 Human Inquiry
SCDBC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 IL13 Mouse IL4 Mouse Inquiry
SCDBC-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 IL13 Mouse IL17 Mouse Inquiry
BSDBC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 IL13 Human IL4 Human Inquiry
BSDBC-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 IL13 Human IL17 Human Inquiry
BSDBC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 IL13 Mouse IL4 Mouse Inquiry
BSDBC-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 IL13 Mouse IL17 Mouse Inquiry
SCDBF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc IL13 Human IL4 Human Inquiry
SCDBF-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc IL13 Human IL17 Human Inquiry
SCDBF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc IL13 Mouse IL4 Mouse Inquiry
SCDBF-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc IL13 Mouse IL17 Mouse Inquiry
BSFVF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc IL13 Human IL4 Human Inquiry
BSFVF-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc IL13 Human IL17 Human Inquiry
BSFVF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc IL13 Mouse IL4 Mouse Inquiry
BSFVF-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc IL13 Mouse IL17 Mouse Inquiry
BSDBF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc IL13 Human IL4 Human Inquiry
BSDBF-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc IL13 Human IL17 Human Inquiry
BSDBF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc IL13 Mouse IL4 Mouse Inquiry
BSDBF-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc IL13 Mouse IL17 Mouse Inquiry
BSTF-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL13 Human IL4 Human Inquiry
BSTF-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL13 Human IL17 Human Inquiry
BSTF-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL13 Mouse IL4 Mouse Inquiry
BSTF-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL13 Mouse IL17 Mouse Inquiry
BSCFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-Fc) Human scFv-Fc IL13 Human IL4 Human Inquiry
BSCFV-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scFv-Fc) Human scFv-Fc IL13 Human IL17 Human Inquiry
BSCFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-Fc) Human scFv-Fc IL13 Mouse IL4 Mouse Inquiry
BSCFV-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-Fc) Human scFv-Fc IL13 Mouse IL17 Mouse Inquiry
MNAB-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Miniantibody) Human Miniantibody IL13 Human IL4 Human Inquiry
MNAB-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Miniantibody) Human Miniantibody IL13 Human IL17 Human Inquiry
MNAB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Miniantibody) Human Miniantibody IL13 Mouse IL4 Mouse Inquiry
MNAB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Miniantibody) Human Miniantibody IL13 Mouse IL17 Mouse Inquiry
BSFC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL13 Human IL4 Human Inquiry
BSFC-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL13 Human IL17 Human Inquiry
BSFC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL13 Mouse IL4 Mouse Inquiry
BSFC-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL13 Mouse IL17 Mouse Inquiry
BSCC-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL13 Human IL4 Human Inquiry
BSCC-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL13 Human IL17 Human Inquiry
BSCC-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL13 Mouse IL4 Mouse Inquiry
BSCC-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL13 Mouse IL17 Mouse Inquiry
BIBD-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Bibody) Human Bibody IL13 Human IL4 Human Inquiry
BIBD-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Bibody) Human Bibody IL13 Human IL17 Human Inquiry
BIBD-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Bibody) Human Bibody IL13 Mouse IL4 Mouse Inquiry
BIBD-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Bibody) Human Bibody IL13 Mouse IL17 Mouse Inquiry
FABFV-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Fab-Fv) Human Fab-Fv IL13 Human IL4 Human Inquiry
FABFV-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Fab-Fv) Human Fab-Fv IL13 Human IL17 Human Inquiry
FABFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-Fv) Human Fab-Fv IL13 Mouse IL4 Mouse Inquiry
FABFV-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Fab-Fv) Human Fab-Fv IL13 Mouse IL17 Mouse Inquiry
MiniB-H338 Recombinant Human Anti-IL13 x Human Anti-IL4 Bispecific Antibody (Minibody) Human Minibody IL13 Human IL4 Human Inquiry
MiniB-H337 Recombinant Human Anti-IL13 x Human Anti-IL17 Bispecific Antibody (Minibody) Human Minibody IL13 Human IL17 Human Inquiry
MiniB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Minibody) Human Minibody IL13 Mouse IL4 Mouse Inquiry
MiniB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Minibody) Human Minibody IL13 Mouse IL17 Mouse Inquiry
SCDB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL13 Human IL4 Human Inquiry
SCDB-H336 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL13 Human IL17 Human Inquiry
FABIG-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) Human Fab-IgG IL13 Human IL4 Human Inquiry
FABIG-H336 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (Fab-IgG) Human Fab-IgG IL13 Human IL17 Human Inquiry
TRIB-H339 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL13 Human IL4 Human Inquiry
TRIB-H338 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL13 Human IL17 Human Inquiry
BSIG-H337 Human Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-IgG) Human IgG-IgG IL13 Human IL4 Human Inquiry
BSIG-H336 Human Anti-IL13 x Anti-IL17 Bispecific Antibody (IgG-IgG) Human IgG-IgG IL13 Human IL17 Human Inquiry
CROSSAB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (CrossMab) Human CrossMab IL13 Human IL4 Human Inquiry
CROSSAB-H336 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (CrossMab) Human CrossMab IL13 Human IL17 Human Inquiry
IGFV-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-scFv) Human IgG-scFv IL13 Human IL4 Human Inquiry
IGFV-H336 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (IgG-scFv) Human IgG-scFv IL13 Human IL17 Human Inquiry
BSDB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody) Human Diabody IL13 Human IL4 Human Inquiry
BSDB-H336 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (Diabody) Human Diabody IL13 Human IL17 Human Inquiry
BSFAB-H337 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem Fab) Human Tandem Fab IL13 Human IL4 Human Inquiry
BSFAB-H336 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (Tandem Fab) Human Tandem Fab IL13 Human IL17 Human Inquiry
BSFV-H335 Recombinant Human Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv) Human Tandem scFv IL13 Human IL4 Human Inquiry
BSFV-H334 Recombinant Human Anti-IL13 x Anti-IL17 Bispecific Antibody (Tandem scFv) Human Tandem scFv IL13 Human IL17 Human Inquiry
SCDB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL13 Mouse IL4 Mouse Inquiry
SCDB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL13 Mouse IL17 Mouse Inquiry
FABIG-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-IgG) Human Fab-IgG IL13 Mouse IL4 Mouse Inquiry
FABIG-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Fab-IgG) Human Fab-IgG IL13 Mouse IL17 Mouse Inquiry
TRIB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL13 Mouse IL4 Mouse Inquiry
TRIB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL13 Mouse IL17 Mouse Inquiry
BSIG-173 Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-IgG) Human IgG-IgG IL13 Mouse IL4 Mouse Inquiry
BSIG-172 Anti-IL13 x Anti-IL17 Bispecific Antibody (IgG-IgG) Human IgG-IgG IL13 Mouse IL17 Mouse Inquiry
CROSSAB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (CrossMab) Human CrossMab IL13 Mouse IL4 Mouse Inquiry
CROSSAB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (CrossMab) Human CrossMab IL13 Mouse IL17 Mouse Inquiry
IGFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (IgG-scFv) Human IgG-scFv IL13 Mouse IL4 Mouse Inquiry
IGFV-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (IgG-scFv) Human IgG-scFv IL13 Mouse IL17 Mouse Inquiry
BSDB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Diabody) Human Diabody IL13 Mouse IL4 Mouse Inquiry
BSDB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Diabody) Human Diabody IL13 Mouse IL17 Mouse Inquiry
BSFAB-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem Fab) Human Tandem Fab IL13 Mouse IL4 Mouse Inquiry
BSFAB-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Tandem Fab) Human Tandem Fab IL13 Mouse IL17 Mouse Inquiry
BSFV-173 Recombinant Anti-IL13 x Anti-IL4 Bispecific Antibody (Tandem scFv) Human Tandem scFv IL13 Mouse IL4 Mouse Inquiry
BSFV-172 Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (Tandem scFv) Human Tandem scFv IL13 Mouse IL17 Mouse Inquiry

Background

Interleukin 13 (IL-13), alternatively known as P600, is an immunoregulatory cytokine generated by activated Th2 cells, playing a role in Th2 inflammation. In addition to TH2 cells, IL-13 is generated by other CD4 cells, basophils, mast cells, and NK cells upon activation. IL-13 is implicated in the pathogenesis of IgE-mediated allergic diseases, serving as a mediator of allergic inflammation and playing a role in various conditions, including asthma. Its ability to induce proliferation and IgE synthesis in human B cells has led to its recognition as a potential therapeutic target for asthma treatment. IL-13 engages with a receptor shared with IL-4, initiating downstream signaling through the STAT5 and JAK pathways.

Schematic representation of the complex receptor system mediating IL-4 and IL-13 signaling. (Marone, et al., 2019) Fig.1 Schematic representation of the complex receptor system mediating IL-4 and IL-13 signaling.1

Reference

  1. Marone, Giancarlo, et al. "The intriguing role of interleukin 13 in the pathophysiology of asthma." Frontiers in pharmacology 10 (2019): 1387.
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