IL2RA Bispecific Antibodies - Creative Biolabs

Product List Background

Product List

CAT#	Product Name	Species Reactivity	BsAb Type	Target 1	Host Animal 1	Target 2	Host Animal 2	INQUIRY
KN-0825-N64	Recombinan Human Anti-CTLA4 x Human Anti-IL2RA Bispecific Antibody (Fab-scFv-Fc)	Human	Fab-scFv/sdAb-Fc	CTLA4	Human	IL2RA	Human	Inquiry
KN-0825-N35	Recombinan Human Anti-CTLA4 x Human Anti-IL2RA Bispecific Antibody (IgG(H)-scFv)	Human	IgG-scFv	CTLA4	Human	IL2RA	Human	Inquiry

Background

IL-2R (Interleukin 2 receptor) is a heterotrimeric protein that is expressed, either temporary or permanent, on the surface of almost all hematopoietic cells involving lymphoid linages T, B, and NK cells, and myeloid. IL-2R can bind and respond to a cytokine referred to IL-2. IL-2R consists of three distinct polypeptide subunits including alpha chain (IL-2Rα, CD25), beta chain (IL-2Rβ, CD122), and gamma chain (IL-2Rγc, CD132). IL-2Rα (alias: Tac antigen or p55) of human is located on chromosome 10p14-15. IL-2Rβ is encoded on chromosome 22q11.2-12 and the gene for the IL-2Rγc is on chromosome Xq13. Assembly of these subunits of the receptor is significant for transduction signal into B and T cells.

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