Home > Products > By Targets > LFA-1
LFA-1 Bispecific Antibodies
Product List Background

Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem Diabody) Mouse Tandem Diabody B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCIGG-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scIgG) Mouse Single chain IgGs B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FVTIG-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv4-Ig) Mouse scFv4-Ig B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSSG-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-IgG) Mouse scFv-IgG B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
IGLFV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG(L)-scFv) Mouse IgG-scFv B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSGV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG-Fv) Mouse IgG-Fv B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDG-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fv-IgG) Mouse Fv-IgG B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BABFV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (F(ab')2-scFv2) Mouse F(ab')2-scFv2 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABVC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-Fc) Mouse Fab-scFv/sdAb-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCDBC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scDiabody-CH3) Mouse scDiabody-CH3 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDBC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-CH3) Mouse Diabody-CH3 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCDBF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scDiabody-Fc) Mouse scDiabody-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFVF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem scFv-Fc) Mouse Tandem scFv-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDBF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-Fc) Mouse Diabody-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSTF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-Fc-scFv) Mouse scFv-Fc-scFv B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSCFV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-Fc) Mouse scFv-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
MNAB-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Miniantibody) Mouse Miniantibody B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-CH3) Mouse scFv-CH3 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSCC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-CH1/CL) Mouse scFv-CH1/CL B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BIBD-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Bibody) Mouse Bibody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
MiniB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Minibody) Mouse Minibody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCDB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Single-chain Diabody) Mouse Single-chain Diabody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABIG-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-IgG) Mouse Fab-IgG B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
TRIB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-scFv) Mouse Fab-scFv-scFv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSIG-014 Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG-IgG) Mouse IgG-IgG B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
CROSSAB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (CrossMab) Mouse CrossMab B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
IGFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG-scFv) Mouse IgG-scFv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody) Mouse Diabody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFAB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry

Background

Lymphocyte function-associated antigen 1 (LFA-1), also known as integrin subunit alpha L (ITGAL), is a heterodimeric β2-integrin receptor. LFA-1 consists of a beta submit and an alpha submit with an I domain and an ICAM binding site, allowing the binding of its ligands ICAMs (-1 to -5) and JAM-A. LFA-1 is prominently expressed on leukocytes, involved with the differentiation, emigration, arrest, and effector functions of leukocytes. Interactions of LFA-1/ICAM-1 induce signaling pathways that result in the high-affinity contact between Treg and DC and conformational change, thus causing lethargy of DC and inhibiting T cell activation and proliferation. LFA-1 also plays a role in homotypic T cell-T cell interactions, which promote the formation of T cell memory and Th1 differentiation responses. Additionally, recent studies have reported that dysregulation of LFA-1 causes specific pathologies in immunological synapses. LFA-1 and related molecules have attracted a lot of attention as crucial regulators in multiple signaling pathways.

Role of LFA-1-mediated contact for T cell response and suppression. (Klaus, et al, 2023) Fig.1 Role of LFA-1-mediated contact for T cell response and suppression.1

Reference

  1. Klaus, Tanja, et al. "The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells—Lessons Learned from Different Transgenic Mouse Models." International Journal of Molecular Sciences 24.7 (2023): 6331.
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related Sections

SERVICES

PRODUCTS

PLATFORMS

quality
ISO 9001 Certified - Creative Biolabs Quality Management System.
© 2026 Creative Biolabs. All Rights Reserved.