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NkG2C & CD30 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
KN-0725-N93 Recombinant Human Anti-NkG2C x Mouse Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab NkG2C Human CD30 Mouse Inquiry
KN-0725-N57 Recombinant Human Anti-NkG2C x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc) Human scFv-Fc NkG2C Human CD30 Mouse Inquiry
KN-0725-N19 Recombinant Human Anti-NkG2C x Mouse Anti-CD30 Bispecific Antibody (IgG(H)-scFv) Human IgG-scFv NkG2C Human CD30 Mouse Inquiry
BIBD-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Bibody) Human Bibody CD30 Mouse CD64 Mouse Inquiry
BIBD-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD30 Mouse Inquiry
BIBD-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Bibody) Human Bibody CD28 Mouse CD30 Mouse Inquiry
BIBD-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Bibody) Human Bibody CD16 Mouse CD30 Mouse Inquiry
FABFV-H286 Recombinant Human Anti-CD30 x Human Anti-CD64 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD30 Human CD64 Human Inquiry
FABFV-H241 Recombinant Human Anti-CD3 x Human Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human CD30 Human Inquiry
FABFV-H231 Recombinant Human Anti-CD28 x Human Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Human CD30 Human Inquiry
FABFV-H211 Recombinant Human Anti-CD16 x Human Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Human CD30 Human Inquiry
FABFV-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD30 Mouse CD64 Mouse Inquiry
FABFV-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD30 Mouse Inquiry
FABFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD28 Mouse CD30 Mouse Inquiry
FABFV-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD16 Mouse CD30 Mouse Inquiry
MiniB-H286 Recombinant Human Anti-CD30 x Human Anti-CD64 Bispecific Antibody (Minibody) Human Minibody CD30 Human CD64 Human Inquiry
MiniB-H241 Recombinant Human Anti-CD3 x Human Anti-CD30 Bispecific Antibody (Minibody) Human Minibody CD3 Human CD30 Human Inquiry
MiniB-H231 Recombinant Human Anti-CD28 x Human Anti-CD30 Bispecific Antibody (Minibody) Human Minibody CD28 Human CD30 Human Inquiry
MiniB-H211 Recombinant Human Anti-CD16 x Human Anti-CD30 Bispecific Antibody (Minibody) Human Minibody CD16 Human CD30 Human Inquiry
MiniB-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Minibody) Human Minibody CD30 Mouse CD64 Mouse Inquiry
MiniB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Minibody) Human Minibody CD3 Mouse CD30 Mouse Inquiry
MiniB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Minibody) Human Minibody CD28 Mouse CD30 Mouse Inquiry
MiniB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Minibody) Human Minibody CD16 Mouse CD30 Mouse Inquiry
SCTB-H179 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD30 Human CD64 Human Inquiry
SCTB-H135 Recombinant Human Anti-CD30 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human CD30 Human Inquiry
SCTB-H126 Recombinant Human Anti-CD30 x Human Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD28 Human CD30 Human Inquiry
SCTB-H111 Recombinant Human Anti-CD30 x Human Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 Human CD30 Human Inquiry
SCDB-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD30 Human CD64 Human Inquiry
SCDB-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human CD30 Human Inquiry
SCDB-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 Human CD30 Human Inquiry
SCDB-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 Human CD30 Human Inquiry
FABIG-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD30 Human CD64 Human Inquiry
FABIG-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human CD30 Human Inquiry
FABIG-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 Human CD30 Human Inquiry
FABIG-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 Human CD30 Human Inquiry
TRIB-H286 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD30 Human CD64 Human Inquiry
TRIB-H241 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human CD30 Human Inquiry
TRIB-H231 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Human CD30 Human Inquiry
TRIB-H211 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Human CD30 Human Inquiry
BSIG-H284 Human Anti-CD30 x Anti-CD64 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD30 Human CD64 Human Inquiry
BSIG-H239 Human Anti-CD3 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human CD30 Human Inquiry
BSIG-H229 Human Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Human CD30 Human Inquiry
BSIG-H209 Human Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 Human CD30 Human Inquiry
CROSSAB-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (CrossMab) Human CrossMab CD30 Human CD64 Human Inquiry
CROSSAB-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human CD30 Human Inquiry
CROSSAB-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD28 Human CD30 Human Inquiry
CROSSAB-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD16 Human CD30 Human Inquiry
IGFV-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD30 Human CD64 Human Inquiry
IGFV-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human CD30 Human Inquiry
IGFV-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Human CD30 Human Inquiry
IGFV-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 Human CD30 Human Inquiry
BSDB-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Diabody) Human Diabody CD30 Human CD64 Human Inquiry
BSDB-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD3 Human CD30 Human Inquiry
BSDB-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD28 Human CD30 Human Inquiry
BSDB-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD16 Human CD30 Human Inquiry
BSFAB-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD30 Human CD64 Human Inquiry
BSFAB-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human CD30 Human Inquiry
BSFAB-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Human CD30 Human Inquiry
BSFAB-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 Human CD30 Human Inquiry
BSFV-H284 Recombinant Human Anti-CD30 x Anti-CD64 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD30 Human CD64 Human Inquiry
BSFV-H239 Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human CD30 Human Inquiry
BSFV-H229 Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Human CD30 Human Inquiry
BSFV-H209 Recombinant Human Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 Human CD30 Human Inquiry
SCTB-083 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD30 Mouse CD64 Mouse Inquiry
SCTB-037 Recombinant Anti-CD30 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse CD30 Mouse Inquiry
SCTB-027 Recombinant Anti-CD30 x Anti-CD28 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD28 Mouse CD30 Mouse Inquiry
SCTB-011 Recombinant Anti-CD30 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 Mouse CD30 Mouse Inquiry
SCDB-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD30 Mouse CD64 Mouse Inquiry
SCDB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse CD30 Mouse Inquiry
SCDB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD28 Mouse CD30 Mouse Inquiry
SCDB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 Mouse CD30 Mouse Inquiry
FABIG-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD30 Mouse CD64 Mouse Inquiry
FABIG-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse CD30 Mouse Inquiry
FABIG-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 Mouse CD30 Mouse Inquiry
FABIG-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 Mouse CD30 Mouse Inquiry
TRIB-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD30 Mouse CD64 Mouse Inquiry
TRIB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse CD30 Mouse Inquiry
TRIB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse CD30 Mouse Inquiry
TRIB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Mouse CD30 Mouse Inquiry
BSIG-110 Anti-CD30 x Anti-CD64 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD30 Mouse CD64 Mouse Inquiry
BSIG-065 Anti-CD3 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse CD30 Mouse Inquiry
BSIG-055 Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse CD30 Mouse Inquiry
BSIG-034 Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 Mouse CD30 Mouse Inquiry
CROSSAB-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (CrossMab) Human CrossMab CD30 Mouse CD64 Mouse Inquiry
CROSSAB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse CD30 Mouse Inquiry
CROSSAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse CD30 Mouse Inquiry
CROSSAB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (CrossMab) Human CrossMab CD16 Mouse CD30 Mouse Inquiry
IGFV-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD30 Mouse CD64 Mouse Inquiry
IGFV-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse CD30 Mouse Inquiry
IGFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse CD30 Mouse Inquiry
IGFV-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 Mouse CD30 Mouse Inquiry
BSDB-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Diabody) Human Diabody CD30 Mouse CD64 Mouse Inquiry
BSDB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse CD30 Mouse Inquiry
BSDB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD28 Mouse CD30 Mouse Inquiry
BSDB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Diabody) Human Diabody CD16 Mouse CD30 Mouse Inquiry
BSFAB-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD30 Mouse CD64 Mouse Inquiry
BSFAB-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD30 Mouse Inquiry
BSFAB-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse CD30 Mouse Inquiry
BSFAB-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 Mouse CD30 Mouse Inquiry
BSFV-110 Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD30 Mouse CD64 Mouse Inquiry
BSFV-065 Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD30 Mouse Inquiry
BSFV-055 Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse CD30 Mouse Inquiry
BSFV-034 Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 Mouse CD30 Mouse Inquiry

Background

Natural killer group 2C (NkG2C), a C-type lectin-like activating receptor on NK cells, synergizes with CD94 to form heterodimers that bind HLA-E, enhancing cytotoxic responses against infected or malignant cells. Cluster of differentiation 30 (CD30), a tumor necrosis factor receptor superfamily member, is overexpressed in classical Hodgkin lymphoma and anaplastic large cell lymphoma, making it a validated therapeutic target. Bispecific antibodies targeting NkG2C and CD30 simultaneously bridge NK cell activation with tumor antigen engagement. These molecules recruit CD16A-positive NK cells to CD30+ malignancies, promoting antibody-dependent cellular cytotoxicity and cytokine-mediated immune amplification. Such dual-targeting strategies demonstrate promising applications in hematological oncology, particularly for relapsed/refractory lymphomas where conventional therapies fail. By leveraging NK cell surveillance mechanisms and tumor-specific surface markers, this approach enables precise elimination of malignant cells while sparing healthy tissues.

The diverse signaling pathways mediated by NkG2C and CD30. (OA Literature)Fig.1 NkG2C and CD30 signaling pathways.1,2

References

  1. Wang, Xiaotong et al. "Implications of NKG2A in immunity and immune-mediated diseases." Frontiers in Immunology vol. 13 960852. 10 Aug. 2022, doi:10.3389/fimmu.2022.960852. Distributed under Open Access license CC BY 4.0. The image was modified by extracting and using only part of the original image.
  2. van der Weyden, C A et al. "Understanding CD30 biology and therapeutic targeting: a historical perspective providing insight into future directions." Blood Cancer Journal vol. 7,9 e603. 8 Sep. 2017, doi:10.1038/bcj.2017.85. Distributed under Open Access license CC BY 4.0, without modification.
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