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PD-L1 & EGFR Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
KN-0825-N46 Recombinant Human Anti-PD-L1 x Human Anti-EGFR Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc PD-L1 Human EGFR Human Inquiry
KN-0825-N17 Recombinant Human Anti-PD-L1 x Human Anti-EGFR Bispecific Antibody (IgG(H)-scFv) Human IgG-scFv PD-L1 Human EGFR Human Inquiry
FABIG-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (Fab-IgG) Human Fab-IgG EGFR Mouse HER2 Mouse Inquiry
FABIG-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (Fab-IgG) Human Fab-IgG EGFR Mouse MET Mouse Inquiry
FABIG-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG doxorubicin Mouse EGFR Mouse Inquiry
FABIG-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD89 Mouse EGFR Mouse Inquiry
FABIG-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD64 Mouse EGFR Mouse Inquiry
FABIG-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse EGFR Mouse Inquiry
FABIG-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD28 Mouse EGFR Mouse Inquiry
FABIG-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD2 Mouse EGFR Mouse Inquiry
FABIG-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 Mouse EGFR Mouse Inquiry
FABIG-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Fab-IgG) Human Fab-IgG CD133 Mouse EGFR Mouse Inquiry
TRIB-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv EGFR Mouse ZnO Mouse Inquiry
TRIB-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv EGFR Mouse IGF1R Mouse Inquiry
TRIB-156 Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv EGFR Mouse HER3 Mouse Inquiry
TRIB-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv EGFR Mouse HER2 Mouse Inquiry
TRIB-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv EGFR Mouse MET Mouse Inquiry
TRIB-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv doxorubicin Mouse EGFR Mouse Inquiry
TRIB-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD89 Mouse EGFR Mouse Inquiry
TRIB-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD64 Mouse EGFR Mouse Inquiry
TRIB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse EGFR Mouse Inquiry
TRIB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD28 Mouse EGFR Mouse Inquiry
TRIB-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD2 Mouse EGFR Mouse Inquiry
TRIB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Mouse EGFR Mouse Inquiry
TRIB-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD133 Mouse EGFR Mouse Inquiry
BSIG-158 Anti-EGFR x Anti-ZnO Bispecific Antibody (IgG-IgG) Human IgG-IgG EGFR Mouse ZnO Mouse Inquiry
BSIG-157 Anti-EGFR x Anti-IGF1R Bispecific Antibody (IgG-IgG) Human IgG-IgG EGFR Mouse IGF1R Mouse Inquiry
BSIG-156 Anti-EGFR x Anti-HER3 Bispecific Antibody (IgG-IgG) Human IgG-IgG EGFR Mouse HER3 Mouse Inquiry
BSIG-155 Anti-EGFR x Anti-HER2 Bispecific Antibody (IgG-IgG) Human IgG-IgG EGFR Mouse HER2 Mouse Inquiry
BSIG-154 Anti-EGFR x Anti-MET Bispecific Antibody (IgG-IgG) Human IgG-IgG EGFR Mouse MET Mouse Inquiry
BSIG-151 Anti-doxorubicin x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG doxorubicin Mouse EGFR Mouse Inquiry
BSIG-132 Anti-CD89 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD89 Mouse EGFR Mouse Inquiry
BSIG-125 Anti-CD64 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD64 Mouse EGFR Mouse Inquiry
BSIG-077 Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse EGFR Mouse Inquiry
BSIG-058 Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD28 Mouse EGFR Mouse Inquiry
BSIG-046 Anti-CD2 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD2 Mouse EGFR Mouse Inquiry
BSIG-036 Anti-CD16 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 Mouse EGFR Mouse Inquiry
BSIG-031 Anti-CD133 x Anti-EGFR Bispecific Antibody (IgG-IgG) Human IgG-IgG CD133 Mouse EGFR Mouse Inquiry
CROSSAB-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (CrossMab) Human CrossMab EGFR Mouse ZnO Mouse Inquiry
CROSSAB-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (CrossMab) Human CrossMab EGFR Mouse IGF1R Mouse Inquiry
CROSSAB-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (CrossMab) Human CrossMab EGFR Mouse HER2 Mouse Inquiry
CROSSAB-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (CrossMab) Human CrossMab EGFR Mouse MET Mouse Inquiry
CROSSAB-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab doxorubicin Mouse EGFR Mouse Inquiry
CROSSAB-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD89 Mouse EGFR Mouse Inquiry
CROSSAB-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD64 Mouse EGFR Mouse Inquiry
CROSSAB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse EGFR Mouse Inquiry
CROSSAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD28 Mouse EGFR Mouse Inquiry
CROSSAB-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD2 Mouse EGFR Mouse Inquiry
CROSSAB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD16 Mouse EGFR Mouse Inquiry
CROSSAB-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (CrossMab) Human CrossMab CD133 Mouse EGFR Mouse Inquiry
IGFV-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (IgG-scFv) Human IgG-scFv EGFR Mouse ZnO Mouse Inquiry
IGFV-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (IgG-scFv) Human IgG-scFv EGFR Mouse IGF1R Mouse Inquiry
IGFV-156 Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (IgG-scFv) Human IgG-scFv EGFR Mouse HER3 Mouse Inquiry
IGFV-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (IgG-scFv) Human IgG-scFv EGFR Mouse HER2 Mouse Inquiry
IGFV-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (IgG-scFv) Human IgG-scFv EGFR Mouse MET Mouse Inquiry
IGFV-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv doxorubicin Mouse EGFR Mouse Inquiry
IGFV-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD89 Mouse EGFR Mouse Inquiry
IGFV-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD64 Mouse EGFR Mouse Inquiry
IGFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse EGFR Mouse Inquiry
IGFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD28 Mouse EGFR Mouse Inquiry
IGFV-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD2 Mouse EGFR Mouse Inquiry
IGFV-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 Mouse EGFR Mouse Inquiry
IGFV-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (IgG-scFv) Human IgG-scFv CD133 Mouse EGFR Mouse Inquiry
BSDB-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (Diabody) Human Diabody EGFR Mouse ZnO Mouse Inquiry
BSDB-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Diabody) Human Diabody EGFR Mouse IGF1R Mouse Inquiry
BSDB-156 Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (Diabody) Human Diabody EGFR Mouse HER3 Mouse Inquiry
BSDB-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (Diabody) Human Diabody EGFR Mouse HER2 Mouse Inquiry
BSDB-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (Diabody) Human Diabody EGFR Mouse MET Mouse Inquiry
BSDB-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody doxorubicin Mouse EGFR Mouse Inquiry
BSDB-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD89 Mouse EGFR Mouse Inquiry
BSDB-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD64 Mouse EGFR Mouse Inquiry
BSDB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD3 Mouse EGFR Mouse Inquiry
BSDB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD28 Mouse EGFR Mouse Inquiry
BSDB-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD2 Mouse EGFR Mouse Inquiry
BSDB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD16 Mouse EGFR Mouse Inquiry
BSDB-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Diabody) Human Diabody CD133 Mouse EGFR Mouse Inquiry
BSFV-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv doxorubicin Mouse EGFR Mouse Inquiry
BSFAB-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (Tandem Fab) Human Tandem Fab EGFR Mouse ZnO Mouse Inquiry
BSFAB-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Tandem Fab) Human Tandem Fab EGFR Mouse IGF1R Mouse Inquiry
BSFAB-156 Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (Tandem Fab) Human Tandem Fab EGFR Mouse HER3 Mouse Inquiry
BSFAB-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (Tandem Fab) Human Tandem Fab EGFR Mouse HER2 Mouse Inquiry
BSFAB-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (Tandem Fab) Human Tandem Fab EGFR Mouse MET Mouse Inquiry
BSFAB-151 Recombinant Anti-doxorubicin x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab doxorubicin Mouse EGFR Mouse Inquiry
BSFAB-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD89 Mouse EGFR Mouse Inquiry
BSFAB-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD64 Mouse EGFR Mouse Inquiry
BSFAB-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse EGFR Mouse Inquiry
BSFAB-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD28 Mouse EGFR Mouse Inquiry
BSFAB-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD2 Mouse EGFR Mouse Inquiry
BSFAB-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 Mouse EGFR Mouse Inquiry
BSFAB-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Tandem Fab) Human Tandem Fab CD133 Mouse EGFR Mouse Inquiry
BSFV-158 Recombinant Anti-EGFR x Anti-ZnO Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse ZnO Mouse Inquiry
BSFV-157 Recombinant Anti-EGFR x Anti-IGF1R Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse IGF1R Mouse Inquiry
BSFV-156 Recombinant Anti-EGFR x Anti-HER3 Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse HER3 Mouse Inquiry
BSFV-155 Recombinant Anti-EGFR x Anti-HER2 Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse HER2 Mouse Inquiry
BSFV-154 Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (Tandem scFv) Human Tandem scFv EGFR Mouse MET Mouse Inquiry
BSFV-132 Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD89 Mouse EGFR Mouse Inquiry
BSFV-125 Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD64 Mouse EGFR Mouse Inquiry
BSFV-077 Recombinant Anti-CD3 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse EGFR Mouse Inquiry
BSFV-058 Recombinant Anti-CD28 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD28 Mouse EGFR Mouse Inquiry
BSFV-046 Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD2 Mouse EGFR Mouse Inquiry
BSFV-036 Recombinant Anti-CD16 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 Mouse EGFR Mouse Inquiry
BSFV-031 Recombinant Anti-CD133 x Anti-EGFR Bispecific Antibody (Tandem scFv) Human Tandem scFv CD133 Mouse EGFR Mouse Inquiry

Background

Programmed Death-Ligand 1 (PD-L1) is an immune checkpoint molecule expressed on antigen-presenting cells and various cancer cells, critically involved in modulating T-cell-mediated immune responses. Its interaction with programmed cell death protein 1 (PD-1) on activated T cells delivers inhibitory signals that suppress cytotoxic activity and promote immune tolerance-a mechanism exploited by malignancies to evade immune surveillance. Elevated PD-L1 expression has been documented across multiple tumor types including non-small cell lung carcinoma, melanoma, and gastrointestinal cancers, correlating with advanced disease progression and poorer prognostic outcomes.
EGFR (Epidermal growth factor receptor, also known as ErbB1, ErbB or HER1) is a type I transmembrane glycoprotein involved in normal growth. It belongs to a member of the receptor tyrosine kinase superfamily and makes up the ErbB family with HER2/neu (ErbB-2), HER3 (ErbB-3) and HER4 (ErbB-4). The EGFR gene is encoded on chromosome 7p11.2 and activated by binding to specific protein ligands, such as epidermal growth factor (EGF) and transforming growth factor α (TGF-α). Ligand binding induces EGFR dimerizations resulting in protein-tyrosine kinase activation and cellular signaling. EGFR also plays a role in carcinogenic responses and the increased expression of it in most cases is predictive of tumor progression.
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