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PD-L1 & PD1 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
KN-0825-N49 Recombinant Human Anti-PD-L1 x Human Anti-PD1 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc PD-L1 Human PD1 Human Inquiry
KN-0825-N20 Recombinant Human Anti-PD-L1 x Human Anti-PD1 Bispecific Antibody (IgG(H)-scFv) Human IgG-scFv PD-L1 Human PD1 Human Inquiry
FABFV-H315 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CTLA4 Human PD1 Human Inquiry
FABFV-H274 Recombinant Human Anti-CD3 x Human Anti-PD1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human PD1 Human Inquiry
FABFV-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Fab-Fv) Human Fab-Fv PD1 Mouse TIM-3 Mouse Inquiry
FABFV-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CTLA4 Mouse PD1 Mouse Inquiry
FABFV-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse PD1 Mouse Inquiry
MiniB-H348 Recombinant Human Anti-PD1 x Human Anti-TIM-3 Bispecific Antibody (Minibody) Human Minibody PD1 Human TIM-3 Human Inquiry
MiniB-H315 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Bispecific Antibody (Minibody) Human Minibody CTLA4 Human PD1 Human Inquiry
MiniB-H274 Recombinant Human Anti-CD3 x Human Anti-PD1 Bispecific Antibody (Minibody) Human Minibody CD3 Human PD1 Human Inquiry
MiniB-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Minibody) Human Minibody PD1 Mouse TIM-3 Mouse Inquiry
MiniB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Minibody) Human Minibody CTLA4 Mouse PD1 Mouse Inquiry
MiniB-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Minibody) Human Minibody CD3 Mouse PD1 Mouse Inquiry
BSFAB-SAR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-SAR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-NGB025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-NGB007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-MEL025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-MEL007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-BGN025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-BGN007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-ABR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-ABR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-PAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-PAP007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-SAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-SAP007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-RTA025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-RTA007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-GEL025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-GEL007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-PE025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-PE007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-DT025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFAB-DT007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-SAR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-SAR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-NGB025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-NGB007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-MEL025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-MEL007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-BGN025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-BGN007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-ABR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
BSFV-ABR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Mouse PD1 Mouse Inquiry
BSFV-PAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 Human PD1 Human Inquiry
SCTB-H167 Recombinant Human Anti-PD1 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human PD1 Human Inquiry
SCDB-H346 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody PD1 Human TIM-3 Human Inquiry
SCDB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CTLA4 Human PD1 Human Inquiry
SCDB-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human PD1 Human Inquiry
FABIG-H346 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Fab-IgG) Human Fab-IgG PD1 Human TIM-3 Human Inquiry
FABIG-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-IgG) Human Fab-IgG CTLA4 Human PD1 Human Inquiry
FABIG-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human PD1 Human Inquiry
TRIB-H348 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv PD1 Human TIM-3 Human Inquiry
TRIB-H315 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CTLA4 Human PD1 Human Inquiry
TRIB-H274 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human PD1 Human Inquiry
BSIG-H346 Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (IgG-IgG) Human IgG-IgG PD1 Human TIM-3 Human Inquiry
BSIG-H313 Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CTLA4 Human PD1 Human Inquiry
BSIG-H272 Human Anti-CD3 x Anti-PD1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human PD1 Human Inquiry
CROSSAB-H346 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (CrossMab) Human CrossMab PD1 Human TIM-3 Human Inquiry
CROSSAB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (CrossMab) Human CrossMab CTLA4 Human PD1 Human Inquiry
CROSSAB-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human PD1 Human Inquiry
IGFV-H346 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (IgG-scFv) Human IgG-scFv PD1 Human TIM-3 Human Inquiry
IGFV-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CTLA4 Human PD1 Human Inquiry
IGFV-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human PD1 Human Inquiry
BSDB-H346 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Diabody) Human Diabody PD1 Human TIM-3 Human Inquiry
BSDB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Diabody) Human Diabody CTLA4 Human PD1 Human Inquiry
BSDB-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (Diabody) Human Diabody CD3 Human PD1 Human Inquiry
BSFAB-H346 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem Fab) Human Tandem Fab PD1 Human TIM-3 Human Inquiry
BSFAB-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CTLA4 Human PD1 Human Inquiry
BSFAB-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human PD1 Human Inquiry
BSFV-H345 Recombinant Human Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem scFv) Human Tandem scFv PD1 Human TIM-3 Human Inquiry
BSFV-H313 Recombinant Human Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CTLA4 Human PD1 Human Inquiry
BSFV-H272 Recombinant Human Anti-CD3 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human PD1 Human Inquiry
SCTB-071 Recombinant Anti-PD1 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse PD1 Mouse Inquiry
SCDB-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody PD1 Mouse TIM-3 Mouse Inquiry
SCDB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CTLA4 Mouse PD1 Mouse Inquiry
SCDB-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse PD1 Mouse Inquiry
FABIG-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Fab-IgG) Human Fab-IgG PD1 Mouse TIM-3 Mouse Inquiry
FABIG-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-IgG) Human Fab-IgG CTLA4 Mouse PD1 Mouse Inquiry
FABIG-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse PD1 Mouse Inquiry
TRIB-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv PD1 Mouse TIM-3 Mouse Inquiry
TRIB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CTLA4 Mouse PD1 Mouse Inquiry
TRIB-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse PD1 Mouse Inquiry
BSIG-185 Anti-PD1 x Anti-TIM-3 Bispecific Antibody (IgG-IgG) Human IgG-IgG PD1 Mouse TIM-3 Mouse Inquiry
BSIG-146 Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CTLA4 Mouse PD1 Mouse Inquiry
BSIG-098 Anti-CD3 x Anti-PD1 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse PD1 Mouse Inquiry
CROSSAB-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (CrossMab) Human CrossMab PD1 Mouse TIM-3 Mouse Inquiry
CROSSAB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (CrossMab) Human CrossMab CTLA4 Mouse PD1 Mouse Inquiry
CROSSAB-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse PD1 Mouse Inquiry
IGFV-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (IgG-scFv) Human IgG-scFv PD1 Mouse TIM-3 Mouse Inquiry
IGFV-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CTLA4 Mouse PD1 Mouse Inquiry
IGFV-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse PD1 Mouse Inquiry
BSDB-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Diabody) Human Diabody PD1 Mouse TIM-3 Mouse Inquiry
BSDB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Diabody) Human Diabody CTLA4 Mouse PD1 Mouse Inquiry
BSDB-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse PD1 Mouse Inquiry
BSFV-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem scFv) Human Tandem scFv PD1 Mouse TIM-3 Mouse Inquiry
BSFAB-185 Recombinant Anti-PD1 x Anti-TIM-3 Bispecific Antibody (Tandem Fab) Human Tandem Fab PD1 Mouse TIM-3 Mouse Inquiry
BSFAB-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CTLA4 Mouse PD1 Mouse Inquiry
BSFAB-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse PD1 Mouse Inquiry
BSFV-146 Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CTLA4 Mouse PD1 Mouse Inquiry
BSFV-098 Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PD1 Mouse Inquiry

Background

Programmed Death-Ligand 1 (PD-L1) is an immune checkpoint molecule expressed on antigen-presenting cells and various cancer cells, critically involved in modulating T-cell-mediated immune responses. Its interaction with programmed cell death protein 1 (PD-1) on activated T cells delivers inhibitory signals that suppress cytotoxic activity and promote immune tolerance-a mechanism exploited by malignancies to evade immune surveillance. Elevated PD-L1 expression has been documented across multiple tumor types including non-small cell lung carcinoma, melanoma, and gastrointestinal cancers, correlating with advanced disease progression and poorer prognostic outcomes.
PD-1 or PDCD1 (Programmed cell death 1), also known as CD279, is a cell surface receptor expressed on T cells and pro-B cells, which was firstly isolated from a murine T cell hybridoma and a hematopoietic progenitor cell line in 1992. It is an inducible immune modulatory receptor and belongs to a member of the CD28 receptor family. The expression of PD-1 is significantly involved in programmed cell death of lymphocytes. PD-1 has two ligands that are PD-L1 (B7-H1 or CD274) and PD-L2 (B7-DC or CD273). Upon their interactions, PD-1 plays an active role in negative regulation of T cell responses to antigen stimulation and maintaining peripheral tolerance. Thus, it is regarded as an important immune checkpoint for therapeutic antibodies against cancers.
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