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TACI Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H199 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Tandem Diabody) Human Tandem Diabody BCMA Human TACI Human Inquiry
T-BSDB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Tandem Diabody) Human Tandem Diabody BCMA Mouse TACI Mouse Inquiry
SCIGG-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scIgG) Human Single chain IgGs BCMA Human TACI Human Inquiry
SCIGG-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scIgG) Human Single chain IgGs BCMA Mouse TACI Mouse Inquiry
FVTIG-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scFv4-Ig) Human scFv4-Ig BCMA Human TACI Human Inquiry
FVTIG-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv4-Ig) Human scFv4-Ig BCMA Mouse TACI Mouse Inquiry
BSSG-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scFv-IgG) Human scFv-IgG BCMA Human TACI Human Inquiry
BSSG-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-IgG) Human scFv-IgG BCMA Mouse TACI Mouse Inquiry
IGLFV-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv BCMA Human TACI Human Inquiry
IGLFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv BCMA Mouse TACI Mouse Inquiry
BSGV-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (IgG-Fv) Human IgG-Fv BCMA Mouse TACI Mouse Inquiry
BSGV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (IgG-Fv) Human IgG-Fv BCMA Mouse TACI Mouse Inquiry
BSDG-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Fv-IgG) Human Fv-IgG BCMA Human TACI Human Inquiry
BSDG-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fv-IgG) Human Fv-IgG BCMA Mouse TACI Mouse Inquiry
BABFV-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 BCMA Human TACI Human Inquiry
BABFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 BCMA Mouse TACI Mouse Inquiry
FABVC-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc BCMA Human TACI Human Inquiry
FABVC-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc BCMA Mouse TACI Mouse Inquiry
SCDBC-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 BCMA Human TACI Human Inquiry
SCDBC-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 BCMA Mouse TACI Mouse Inquiry
BSDBC-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 BCMA Human TACI Human Inquiry
BSDBC-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 BCMA Mouse TACI Mouse Inquiry
SCDBF-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc BCMA Human TACI Human Inquiry
SCDBF-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc BCMA Mouse TACI Mouse Inquiry
BSFVF-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc BCMA Human TACI Human Inquiry
BSFVF-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc BCMA Mouse TACI Mouse Inquiry
BSDBF-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Diabody-Fc) Human Diabody-Fc BCMA Human TACI Human Inquiry
BSDBF-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Diabody-Fc) Human Diabody-Fc BCMA Mouse TACI Mouse Inquiry
BSTF-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv BCMA Mouse TACI Mouse Inquiry
BSTF-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv BCMA Mouse TACI Mouse Inquiry
BSCFV-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scFv-Fc) Human scFv-Fc BCMA Mouse TACI Mouse Inquiry
BSCFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-Fc) Human scFv-Fc BCMA Mouse TACI Mouse Inquiry
MNAB-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Miniantibody) Human Miniantibody BCMA Mouse TACI Mouse Inquiry
MNAB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Miniantibody) Human Miniantibody BCMA Mouse TACI Mouse Inquiry
BSFC-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scFv-CH3) Human scFv-CH3 BCMA Mouse TACI Mouse Inquiry
BSFC-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-CH3) Human scFv-CH3 BCMA Mouse TACI Mouse Inquiry
BSCC-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL BCMA Mouse TACI Mouse Inquiry
BSCC-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL BCMA Mouse TACI Mouse Inquiry
BIBD-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Bibody) Human Bibody BCMA Mouse TACI Mouse Inquiry
BIBD-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Bibody) Human Bibody BCMA Mouse TACI Mouse Inquiry
FABFV-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Fab-Fv) Human Fab-Fv BCMA Human TACI Human Inquiry
FABFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-Fv) Human Fab-Fv BCMA Mouse TACI Mouse Inquiry
MiniB-H201 Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Minibody) Human Minibody BCMA Human TACI Human Inquiry
MiniB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Minibody) Human Minibody BCMA Mouse TACI Mouse Inquiry
BSFAB-SAR019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-SAR001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-NGB019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-NGB001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-MEL019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-MEL001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-BGN019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-BGN001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-ABR019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-ABR001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-PAP019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-PAP001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-SAP019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-SAP001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-RTA019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-RTA001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-GEL019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-GEL001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-PE019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-PE001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFAB-DT019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFAB-DT001 Recombinant Anti-BCMA x Anti-TACI Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFV-SAR019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFV-SAR001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFV-NGB019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFV-NGB001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFV-MEL019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFV-MEL001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFV-BGN019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFV-BGN001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFV-ABR019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
BSFV-ABR001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Mouse TACI Mouse Inquiry
BSFV-PAP019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA Human TACI Human Inquiry
SCDB-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody BCMA Human TACI Human Inquiry
FABIG-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-IgG) Human Fab-IgG BCMA Human TACI Human Inquiry
TRIB-H201 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv BCMA Human TACI Human Inquiry
BSIG-H199 Human Anti-BCMA x Anti-TACI Bispecific Antibody (IgG-IgG) Human IgG-IgG BCMA Human TACI Human Inquiry
CROSSAB-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (CrossMab) Human CrossMab BCMA Human TACI Human Inquiry
IGFV-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (IgG-scFv) Human IgG-scFv BCMA Human TACI Human Inquiry
BSDB-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (Diabody) Human Diabody BCMA Human TACI Human Inquiry
BSFAB-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (Tandem Fab) Human Tandem Fab BCMA Human TACI Human Inquiry
BSFV-H199 Recombinant Human Anti-BCMA x Anti-TACI Bispecific Antibody (Tandem scFv) Human Tandem scFv BCMA Human TACI Human Inquiry
SCDB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody BCMA Mouse TACI Mouse Inquiry
FABIG-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-IgG) Human Fab-IgG BCMA Mouse TACI Mouse Inquiry
TRIB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv BCMA Mouse TACI Mouse Inquiry
BSIG-021 Anti-BCMA x Anti-TACI Bispecific Antibody (IgG-IgG) Human IgG-IgG BCMA Mouse TACI Mouse Inquiry
CROSSAB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (CrossMab) Human CrossMab BCMA Mouse TACI Mouse Inquiry
IGFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (IgG-scFv) Human IgG-scFv BCMA Mouse TACI Mouse Inquiry
BSDB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Diabody) Human Diabody BCMA Mouse TACI Mouse Inquiry
BSFAB-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Tandem Fab) Human Tandem Fab BCMA Mouse TACI Mouse Inquiry
BSFV-021 Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Tandem scFv) Human Tandem scFv BCMA Mouse TACI Mouse Inquiry

Background

Transmembrane activator and CAML interactor (TACI), also designated as TNFRSF13B, CD267, and IGAD2, is a transmembrane protein of the TNF receptor family, predominantly expressed on B cell surfaces. Expression of TACI is promoted by B-cell receptor induction via TLR receptors and CD40. TACI was initially identified as a receptor of CAML in T-cells, and then it was reported to bind another two ligands BAFF and APRIL, playing essential roles in humoral immunity. These interactions activate multiple transcription factors including NFAT, AP-1, and NF-kappa-B, and participate in their signaling pathways. It is demonstrated that TACI relieves B-cell activation regulated by BAFF, and enhances plasma cell differentiation as well as T-cell independent antibody responses. TACI deficiency reduces the production of antibodies, which weakens the protection of the body against environmental infections.

Schematic overview of the TACI network in B-cells. (Salzer, et al, 2021) Fig.1 Schematic overview of the TACI network in B-cells.1

Reference

  1. Salzer, Ulrich, and Bodo Grimbacher. "TACI deficiency—a complex system out of balance." Current Opinion in Immunology 71 (2021): 81-88.
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