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VEGFB Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H349 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Tandem Diabody) Human Tandem Diabody VEGFB Human VEGF Human Inquiry
T-BSDB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Tandem Diabody) Human Tandem Diabody VEGFB Mouse VEGF Mouse Inquiry
SCIGG-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scIgG) Human Single chain IgGs VEGFB Human VEGF Human Inquiry
SCIGG-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scIgG) Human Single chain IgGs VEGFB Mouse VEGF Mouse Inquiry
FVTIG-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv4-Ig) Human scFv4-Ig VEGFB Human VEGF Human Inquiry
FVTIG-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv4-Ig) Human scFv4-Ig VEGFB Mouse VEGF Mouse Inquiry
BSSG-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-IgG) Human scFv-IgG VEGFB Human VEGF Human Inquiry
BSSG-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-IgG) Human scFv-IgG VEGFB Mouse VEGF Mouse Inquiry
IGLFV-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv VEGFB Human VEGF Human Inquiry
IGLFV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv VEGFB Mouse VEGF Mouse Inquiry
BSGV-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (IgG-Fv) Human IgG-Fv VEGFB Mouse VEGF Mouse Inquiry
BSGV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG-Fv) Human IgG-Fv VEGFB Mouse VEGF Mouse Inquiry
BSDG-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Fv-IgG) Human Fv-IgG VEGFB Human VEGF Human Inquiry
BSDG-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fv-IgG) Human Fv-IgG VEGFB Mouse VEGF Mouse Inquiry
BABFV-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 VEGFB Human VEGF Human Inquiry
BABFV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 VEGFB Mouse VEGF Mouse Inquiry
FABVC-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc VEGFB Human VEGF Human Inquiry
FABVC-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc VEGFB Mouse VEGF Mouse Inquiry
SCDBC-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 VEGFB Human VEGF Human Inquiry
SCDBC-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 VEGFB Mouse VEGF Mouse Inquiry
BSDBC-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 VEGFB Human VEGF Human Inquiry
BSDBC-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 VEGFB Mouse VEGF Mouse Inquiry
SCDBF-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc VEGFB Human VEGF Human Inquiry
SCDBF-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc VEGFB Mouse VEGF Mouse Inquiry
BSFVF-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc VEGFB Human VEGF Human Inquiry
BSFVF-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc VEGFB Mouse VEGF Mouse Inquiry
BSDBF-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Diabody-Fc) Human Diabody-Fc VEGFB Human VEGF Human Inquiry
BSDBF-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody-Fc) Human Diabody-Fc VEGFB Mouse VEGF Mouse Inquiry
BSTF-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv VEGFB Mouse VEGF Mouse Inquiry
BSTF-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv VEGFB Mouse VEGF Mouse Inquiry
BSCFV-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-Fc) Human scFv-Fc VEGFB Mouse VEGF Mouse Inquiry
BSCFV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-Fc) Human scFv-Fc VEGFB Mouse VEGF Mouse Inquiry
MNAB-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Miniantibody) Human Miniantibody VEGFB Mouse VEGF Mouse Inquiry
MNAB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Miniantibody) Human Miniantibody VEGFB Mouse VEGF Mouse Inquiry
BSFC-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-CH3) Human scFv-CH3 VEGFB Mouse VEGF Mouse Inquiry
BSFC-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-CH3) Human scFv-CH3 VEGFB Mouse VEGF Mouse Inquiry
BSCC-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL VEGFB Mouse VEGF Mouse Inquiry
BSCC-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL VEGFB Mouse VEGF Mouse Inquiry
BIBD-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Bibody) Human Bibody VEGFB Mouse VEGF Mouse Inquiry
BIBD-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Bibody) Human Bibody VEGFB Mouse VEGF Mouse Inquiry
FABFV-H351 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Fab-Fv) Human Fab-Fv VEGFB Human VEGF Human Inquiry
FABFV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-Fv) Human Fab-Fv VEGFB Mouse VEGF Mouse Inquiry
MiniB-H352 Recombinant Human Anti-VEGFB x Human Anti-VEGF Bispecific Antibody (Minibody) Human Minibody VEGFB Human VEGF Human Inquiry
MiniB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Minibody) Human Minibody VEGFB Mouse VEGF Mouse Inquiry
SCDB-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody VEGFB Human VEGF Human Inquiry
FABIG-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-IgG) Human Fab-IgG VEGFB Human VEGF Human Inquiry
TRIB-H351 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv VEGFB Human VEGF Human Inquiry
BSIG-H349 Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG-IgG) Human IgG-IgG VEGFB Human VEGF Human Inquiry
CROSSAB-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (CrossMab) Human CrossMab VEGFB Human VEGF Human Inquiry
IGFV-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG-scFv) Human IgG-scFv VEGFB Human VEGF Human Inquiry
BSDB-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody) Human Diabody VEGFB Human VEGF Human Inquiry
BSFAB-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (Tandem Fab) Human Tandem Fab VEGFB Human VEGF Human Inquiry
BSFV-H349 Recombinant Human Anti-VEGFB x Anti-VEGF Bispecific Antibody (Tandem scFv) Human Tandem scFv VEGFB Human VEGF Human Inquiry
SCDB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody VEGFB Mouse VEGF Mouse Inquiry
FABIG-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-IgG) Human Fab-IgG VEGFB Mouse VEGF Mouse Inquiry
TRIB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv VEGFB Mouse VEGF Mouse Inquiry
BSIG-190 Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG-IgG) Human IgG-IgG VEGFB Mouse VEGF Mouse Inquiry
CROSSAB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (CrossMab) Human CrossMab VEGFB Mouse VEGF Mouse Inquiry
IGFV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (IgG-scFv) Human IgG-scFv VEGFB Mouse VEGF Mouse Inquiry
BSDB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Diabody) Human Diabody VEGFB Mouse VEGF Mouse Inquiry
BSFAB-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Tandem Fab) Human Tandem Fab VEGFB Mouse VEGF Mouse Inquiry
BSFV-190 Recombinant Anti-VEGFB x Anti-VEGF Bispecific Antibody (Tandem scFv) Human Tandem scFv VEGFB Mouse VEGF Mouse Inquiry

Background

Fig 1. Graphical representation of VEGFB. (Namjoo, et al., 2023)Fig.1 Graphical representation of VEGFB.1

Vascular endothelial growth factor B (VEGFB) is a VEGF family survival factor that affects many different types of vascular cells. It is primarily expressed in the heart, skeletal muscle, and adipose tissue. VEGFB binds to its receptor, VEGFR1, activating downstream signaling pathways. Unlike other VEGF family members, VEGFB has relatively weak angiogenic activity but plays a crucial role in promoting the survival and maintenance of existing blood vessels. VEGFB is involved in cardiac development, protection of cardiomyocytes, neuronal survival, and regulation of energy metabolism in adipose tissue. In the field of cardiovascular disease, VEGFB has potential therapeutic applications. It has shown promise in promoting heart repair and improving heart function following a myocardial infarction. Additionally, targeting VEGFB signaling may have implications in treating obesity-related disorders and neurodegenerative diseases.

Reference

  1. Namjoo, Mohadeseh, et al. “A VEGFB-Based Peptidomimetic Inhibits VEGFR2-Mediated PI3K/Akt/mTOR and PLCγ/ERK Signaling and Elicits Apoptotic, Antiangiogenic, and Antitumor Activities.” Pharmaceuticals (Basel, Switzerland) vol. 16,6 906. 20 Jun. 2023.
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