Home > Products > CEA & GD2 > Recombinant Human Anti-CEA x Human Anti-GD2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin)

Recombinant Human Anti-CEA x Human Anti-GD2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin)  (BSFAB-ABR023)

Recombinant Anti-CEA x Anti-GD2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the abrin-a A chain (ABRa-A) fused to a tandem Fab recognizing CEA and GD2. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver ABRa-A to antigen-specific cells. Then ABR is a type II ribosome inactivating protein (RIP) and can kill the target cells. The bispecific immunotoxin is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Specifications

Targets
CEA & GD2
Type
Bispecific Immunotoxin
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Human
Target 2
GD2
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-CEA x Human Anti-GD2 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) (BSFAB-ABR023). Click the button below to contact us or submit your feedback about this product.

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related products of "CEA & GD2"
Online Inquiry

24x7 Service quality
USA

Tel:
Fax:
Email:

UK

Tel:
Email:

Germany

Tel:
Email: