Home > Products > CTLA4 & PD1 > Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin)

Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin)  (BSFAB-MEL007)

Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Melittin (MEL) fused to a tandem Fab recognizing CTLA4 and PD1. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver MEL to antigen-specific cells. Then MEL is a cytolytic peptide and can kill the target cells. The bispecific immunotoxin is designed for the research of autoimmune disease therapy.

Specifications

Targets
CTLA4 & PD1
Type
Bispecific Immunotoxin
Species Reactivity
Human
Target 1
CTLA4
Host Animal 1
Mouse
Target 2
PD1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Autoimmune disease

Targets

Target 1
CTLA4
Gene ID
UniProt ID
Alternative Names
CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Target 2
PD1
Gene ID
UniProt ID
Alternative Names
PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-CTLA4 x Anti-PD1 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) (BSFAB-MEL007). Click the button below to contact us or submit your feedback about this product.

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related products of "CTLA4 & PD1"
See other bsAb targets related to "PD1"

See other bsAb targets related to "CTLA4"

Online Inquiry

24x7 Service quality
USA

Tel:
Fax:
Email:

UK

Tel:
Email:

Germany

Tel:
Email: