Name: Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin)
SKU: BSFAB-NGB028
Rating: 5 (1 reviews)

Recombinant Anti-EGFR x Anti-HER3 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Nigrin b (NGB) fused to a tandem Fab recognizing EGFR and HER3. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver NGB to antigen-specific cells. Then NGB is a lectin and can kill the target cells. The bispecific immunotoxin is designed for the research of Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

EGFR & HER3

Type

Bispecific Immunotoxin

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Host Animal 1

Human

Host Animal 2

Human

Targets

Target 1

EGFR

Gene ID

1956

UniProt ID

P00533

Alternative Names

EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

Target 2

HER3

Gene ID

2065

UniProt ID

P21860

Alternative Names

ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) (BSFAB-NGB028). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) (CAT#: BSFAB-NGB028)

Specifications

Targets

Customer Reviews and Q&As