Home > Products > PDGFR2 & VEGFR2 > Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin)

Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin)  (BSFAB-SAR017)

Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the α-Sarcin (SAR) fused to a tandem Fab recognizing PDGFR2 and VEGFR2. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver SAR to antigen-specific cells. Then SAR is a ribonuclease which can inhibit protein synthesis and kill the target cells. The bispecific immunotoxin is designed for the research of Cancers therapy.

Specifications

Targets
PDGFR2 & VEGFR2
Type
Bispecific Immunotoxin
Species Reactivity
Human
Target 1
PDGFR2
Host Animal 1
Mouse
Target 2
VEGFR2
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers

Targets

Target 1
PDGFR2
Gene ID
UniProt ID
Alternative Names
PDGFRA; PDGFR2; platelet derived growth factor receptor, alpha polypeptide; CD140a; Pdgfr-2; AI115593; platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGF-R-alpha; PDGF alpha chain; CD140 antigen-like family member A; platelet-derived growth factor alpha receptor; alpha-type platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)
Target 2
VEGFR2
Gene ID
UniProt ID
Alternative Names
FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) (BSFAB-SAR017). Click the button below to contact us or submit your feedback about this product.

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related products of "PDGFR2 & VEGFR2"
See other bsAb targets related to "VEGFR2"

Online Inquiry

24x7 Service quality
USA

Tel:
Fax:
Email:

UK

Tel:
Email:

Germany

Tel:
Email: