Home > Products > CD20 & CD22 > Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin)

Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin)  (CAT#: BSFV-NGB004)

Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Nigrin b (NGB) fused to a tandem scFv recognizing CD20 and CD22. It contains a His-tag at the C/N terminus for affinity purification. This bispecific immunotoxin can deliver NGB to antigen-specific cells. Then NGB is a lectin and can kill the target cells. The bispecific immunotoxin is designed for the research of Lymphoma; Leukemia; Antoimmune disease; Immune dysfunction disease therapy.
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Specifications

Targets
CD20 & CD22
Type
Bispecific Immunotoxin
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma; Leukemia; Antoimmune disease; Immune dysfunction disease

Targets

Target 1
CD20
Gene ID
931
UniProt ID
A0A024R507
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD22
Gene ID
933
UniProt ID
P20273
Alternative Names
CD22; CD22 molecule; Cluster of differentiation 22; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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